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GPCR

NameFree fatty acid receptor 4
SpeciesHomo sapiens (Human)
GeneFFAR4
SynonymO3FAR1
G-protein coupled receptor 120
GPR120
G-protein-coupled receptor GT01
G-protein coupled receptor PGR4
[ Show all ]
DiseaseN/A
Length377
Amino acid sequenceMSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProtQ5NUL3
Protein Data BankN/A
GPCR-HGmod modelQ5NUL3
3D structure modelThis predicted structure model is from GPCR-EXP Q5NUL3.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5339
IUPHAR127
DrugBankBE0003399

Ligand

NameSCHEMBL16482992
Molecular formulaC19H27NO2
IUPAC name2-[3-(3-methylphenyl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
Molecular weight301.43
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP4.7
SynonymsBDBM261575
US9708270, 70
Inchi KeyCONNDFMPTLIBIT-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H27NO2/c1-15-3-2-4-17(13-15)20-11-9-19(10-12-20)7-5-16(6-8-19)14-18(21)22/h2-4,13,16H,5-12,14H2,1H3,(H,21,22)
PubChem CID117886655
ChEMBLN/A
IUPHARN/A
BindingDB261575
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
EC502953.0 nMN/ABindingDB

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