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GPCR

NameFree fatty acid receptor 4
SpeciesHomo sapiens (Human)
GeneFFAR4
SynonymO3FAR1
G-protein coupled receptor 120
GPR120
G-protein-coupled receptor GT01
G-protein coupled receptor PGR4
[ Show all ]
DiseaseN/A
Length377
Amino acid sequenceMSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProtQ5NUL3
Protein Data BankN/A
GPCR-HGmod modelQ5NUL3
3D structure modelThis predicted structure model is from GPCR-EXP Q5NUL3.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5339
IUPHAR127
DrugBankBE0003399

Ligand

NameSCHEMBL16483023
Molecular formulaC24H29NO2
IUPAC name2-[3-(4-phenylphenyl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
Molecular weight363.501
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP6.0
SynonymsBDBM261582
US9708270, 77
Inchi KeyDRNOKCDLXQYIPJ-UHFFFAOYSA-N
Inchi IDInChI=1S/C24H29NO2/c26-23(27)18-19-10-12-24(13-11-19)14-16-25(17-15-24)22-8-6-21(7-9-22)20-4-2-1-3-5-20/h1-9,19H,10-18H2,(H,26,27)
PubChem CID73776960
ChEMBLN/A
IUPHARN/A
BindingDB261582
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
EC504940.0 nMN/ABindingDB

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