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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1B angiotensin II receptor
Species	Rattus norvegicus (Rat)
Gene	Agtr1b
Synonym	Angiotensin II type-1B receptor AT1B AT3
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
UniProt	P29089
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL263
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL145564
Molecular formula	C27H31ClN6O2
IUPAC name	ethyl 2-butyl-6-chloro-4,4-dimethyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidine-5-carboxylate
Molecular weight	507.035
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	2-Butyl-6-chloro-1,4-dihydro-4,4-dimethyl-1-[4-[2-(1H-tetrazol-5-yl)phenyl]benzyl]pyrimidine-5-carboxylic acid ethyl ester BDBM50004155 2-Butyl-6-chloro-4,4-dimethyl-1-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester
Inchi Key	DGKMIANMJJJSJY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31ClN6O2/c1-5-7-12-22-29-27(3,4)23(26(35)36-6-2)24(28)34(22)17-18-13-15-19(16-14-18)20-10-8-9-11-21(20)25-30-32-33-31-25/h8-11,13-16H,5-7,12,17H2,1-4H3,(H,30,31,32,33)
PubChem CID	10006413
ChEMBL	CHEMBL145564
IUPHAR	N/A
BindingDB	50004155
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.1 nM	PMID1469703	BindingDB,ChEMBL

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