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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Bombesin receptor subtype-3
Species	Homo sapiens (Human)
Gene	BRS3
Synonym	bombesin receptor subtype-3 BRS-3 bombesin like receptor 3 BB3 receptor bb3
Disease	Breast cancer Cancer
Length	399
Amino acid sequence	MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
UniProt	P32247
Protein Data Bank	N/A
GPCR-HGmod model	P32247
3D structure model	This predicted structure model is from GPCR-EXP P32247.
BioLiP	N/A
Therapeutic Target Database	T68887
ChEMBL	CHEMBL4080
IUPHAR	40
DrugBank	N/A

Ligand

Name	CHEMBL470806
Molecular formula	C17H14ClNO4
IUPAC name	2-[2-(6-chloro-1,3-benzodioxol-5-yl)ethyl]-5-methoxy-1,3-benzoxazole
Molecular weight	331.752
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.4
Synonyms	BDBM50275840 2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-5-methoxybenzo[d]oxazole
Inchi Key	DIIAHYXBGJGDLG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H14ClNO4/c1-20-11-3-4-14-13(7-11)19-17(23-14)5-2-10-6-15-16(8-12(10)18)22-9-21-15/h3-4,6-8H,2,5,9H2,1H3
PubChem CID	44589926
ChEMBL	CHEMBL470806
IUPHAR	N/A
BindingDB	50275840
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<32000.0 nM	PMID18818070	BindingDB,ChEMBL

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