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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin D2 receptor 2
Species	Mus musculus (Mouse)
Gene	Ptgdr2
Synonym	PGD2 receptor Gpr44 G-protein coupled receptor 44 G protein-coupled receptor 44 DP2 receptor CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells CD294 prostaglandin D2 receptor 2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	382
Amino acid sequence	MANVTLKPLCPLLEEMVQLPNHSNSSLRYIDHVSVLLHGLASLLGLVENGLILFVVGCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNLLLWNPGPDRDTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLRLHHRGRQRTGRFVRLVAAIVVAFVLCWGPYHIFSLLEARAHSVTTLRQLASRGLPFVTSLAFFNSVVNPLLYVFTCPDMLYKLRRSLRAVLESVLVEDSDQSGGLRNRRRRASSTATPASTLLLADRIPQLRPTRLIGWMRRGSAEVPQRV
UniProt	Q9Z2J6
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2291
IUPHAR	339
DrugBank	N/A

Ligand

Name	CHEMBL217053
Molecular formula	C18H13BrN2O4
IUPAC name	2-[4-bromo-2-(1-phenylpyrazole-4-carbonyl)phenoxy]acetic acid
Molecular weight	401.216
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.5
Synonyms	4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxyacetic acid CTK3C5717 Acetic acid, [4-bromo-2-[(1-phenyl-1H-pyrazol-4-yl)carbonyl]phenoxy]- DTXSID10469987 AKOS030574625 870809-73-7 SCHEMBL1994430 BDBM50200271 [ Show all ]
Inchi Key	DMFOOUGJUFPBOG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H13BrN2O4/c19-13-6-7-16(25-11-17(22)23)15(8-13)18(24)12-9-20-21(10-12)14-4-2-1-3-5-14/h1-10H,11H2,(H,22,23)
PubChem CID	11647012
ChEMBL	CHEMBL217053
IUPHAR	N/A
BindingDB	50200271
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	3.2 nM	PMID17154491	BindingDB,ChEMBL

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