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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Bos taurus (Bovine)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
UniProt	P25104
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3374
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL262914
Molecular formula	C48H68N14O12
IUPAC name	(2S)-2-[[(2R)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxy-3-nitrophenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Molecular weight	1033.16
Hydrogen bond acceptor	15
Hydrogen bond donor	12
XlogP	-0.7
Synonyms	N/A
Inchi Key	DXHJTXAOHJMRJT-WTJBABHLSA-N
Inchi ID	InChI=1S/C48H68N14O12/c1-26(2)39(59-41(65)31(55-38(64)24-51-5)13-9-17-53-48(49)50)44(68)56-32(20-29-15-16-37(63)36(21-29)62(73)74)42(66)60-40(27(3)4)45(69)57-33(22-30-23-52-25-54-30)46(70)61-18-10-14-35(61)43(67)58-34(47(71)72)19-28-11-7-6-8-12-28/h6-8,11-12,15-16,21,23,25-27,31-35,39-40,51,63H,9-10,13-14,17-20,22,24H2,1-5H3,(H,52,54)(H,55,64)(H,56,68)(H,57,69)(H,58,67)(H,59,65)(H,60,66)(H,71,72)(H4,49,50,53)/t31-,32-,33-,34-,35+,39-,40-/m0/s1
PubChem CID	44338471
ChEMBL	CHEMBL262914
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Activity	75.0 %	PMID6699877	ChEMBL

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