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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cysteinyl leukotriene receptor 1
Species	Cavia porcellus (Guinea pig)
Gene	CYSLTR1
Synonym	CysLTR1 Cysteinyl leukotriene D4 receptor LTD4 receptor
Disease	N/A for non-human GPCRs
Length	340
Amino acid sequence	MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
UniProt	Q2NNR5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5645
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	107786-78-7
Molecular formula	C28H28N4O6S
IUPAC name	cyclopentyl N-[3-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]benzimidazol-5-yl]carbamate
Molecular weight	548.614
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.3
Synonyms	CHEMBL90933 AC1L3UJK DTXSID30148242 Carbamic acid,[1-[[2-methoxy-4-[[(phenylsulfonyl)amino]carbonyl]phenyl]methyl]-1H-benzimidazol-6-yl]-,cyclopentyl ester (9CI) 4-Cpcab CTK4A5708 ACMC-1BTKD N-(4((6-(((Cyclopentyloxy)carbonyl)amino)benzimidazol-1-yl)methyl)-3-methoxybenzoyl)benzenesulfonamide 4-[6-(Cyclopentyloxycarbonylamino)-1H-benzimidazol-1-ylmethyl]-3-methoxy-N-(phenylsulfonyl)benzamide cyclopentyl N-[3-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]benzimidazol-5-yl]carbamate AKOS030610852 SCHEMBL4461763 [ Show all ]
Inchi Key	FCZVJRPADUYFBI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28N4O6S/c1-37-26-15-19(27(33)31-39(35,36)23-9-3-2-4-10-23)11-12-20(26)17-32-18-29-24-14-13-21(16-25(24)32)30-28(34)38-22-7-5-6-8-22/h2-4,9-16,18,22H,5-8,17H2,1H3,(H,30,34)(H,31,33)
PubChem CID	147132
ChEMBL	CHEMBL90933
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
pKB	9.2 -	PMID2167983	ChEMBL

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