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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cysteinyl leukotriene receptor 1
Species	Cavia porcellus (Guinea pig)
Gene	CYSLTR1
Synonym	CysLTR1 Cysteinyl leukotriene D4 receptor LTD4 receptor
Disease	N/A for non-human GPCRs
Length	340
Amino acid sequence	MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
UniProt	Q2NNR5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5645
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL34740
Molecular formula	C25H15BrN2O5
IUPAC name	6-bromo-4-oxo-2-[3-(quinazolin-2-ylmethoxy)phenyl]chromene-8-carboxylic acid
Molecular weight	503.308
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50064061 SCHEMBL6174551 6-bromo-4-oxo-2-(3-(quinazolin-2-ylmethoxy)phenyl)-4H-chromene-8-carboxylic acid 2-[3-[(2-Quinazolinyl)methoxy]phenyl]-4-oxo-6-bromo-4H-1-benzopyran-8-carboxylic acid 6-Bromo-4-oxo-2-[3-(quinazolin-2-ylmethoxy)-phenyl]-4H-chromene-8-carboxylic acid
Inchi Key	FEGCUSQYQHOKFE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H15BrN2O5/c26-16-9-18-21(29)11-22(33-24(18)19(10-16)25(30)31)14-5-3-6-17(8-14)32-13-23-27-12-15-4-1-2-7-20(15)28-23/h1-12H,13H2,(H,30,31)
PubChem CID	10839186
ChEMBL	CHEMBL34740
IUPHAR	N/A
BindingDB	50064061
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Kd	101.0 nM	PMID9554876	BindingDB,ChEMBL

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