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GPCR

NameNeuropeptides B/W receptor type 1
SpeciesHomo sapiens (Human)
GeneNPBWR1
SynonymG protein-coupled receptor 7
G-protein coupled receptor 7
GPR7
neuropeptides B/W receptor type 1
NPBW1 receptor
DiseaseN/A
Length328
Amino acid sequenceMDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProtP48145
Protein Data BankN/A
GPCR-HGmod modelP48145
3D structure modelThis predicted structure model is from GPCR-EXP P48145.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1293293
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL1985907
Molecular formulaC22H15ClN2O4
IUPAC name5-(1,3-benzodioxol-5-yloxy)-4-chloro-2-(naphthalen-1-ylmethyl)pyridazin-3-one
Molecular weight406.822
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP4.6
SynonymsSR-02000001215
SR-02000001215-1
Inchi KeyFLHDOPXASAXTDO-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H15ClN2O4/c23-21-20(29-16-8-9-18-19(10-16)28-13-27-18)11-24-25(22(21)26)12-15-6-3-5-14-4-1-2-7-17(14)15/h1-11H,12-13H2
PubChem CID53230260
ChEMBLCHEMBL1985907
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
IC503300.0 nMPubChem BioAssay data setChEMBL

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