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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	N-formyl peptide receptor 3
Species	Homo sapiens (Human)
Gene	FPR3
Synonym	FMLP-related receptor II Lxa4r LXA4-R FPRL2 Fprl1 FMLP-R-II FPR3 Formyl peptide receptor-like 2 FMLPY FPRH1 [ Show all ]
Disease	N/A
Length	353
Amino acid sequence	METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
UniProt	P25089
Protein Data Bank	N/A
GPCR-HGmod model	P25089
3D structure model	This predicted structure model is from GPCR-EXP P25089.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	224
DrugBank	N/A

Ligand

Name	CHEMBL2391258
Molecular formula	C26H22BrN3O3
IUPAC name	N-(4-bromophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-phenylpyridazin-1-yl]acetamide
Molecular weight	504.384
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.9
Synonyms	BDBM50435934
Inchi Key	FQGGSTQSDVYXIC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H22BrN3O3/c1-33-23-9-5-6-18(15-23)14-20-16-24(19-7-3-2-4-8-19)29-30(26(20)32)17-25(31)28-22-12-10-21(27)11-13-22/h2-13,15-16H,14,17H2,1H3,(H,28,31)
PubChem CID	71698531
ChEMBL	CHEMBL2391258
IUPHAR	N/A
BindingDB	50435934
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<50000.0 nM	PMID23685570	BindingDB

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