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Name | G-protein coupled receptor 55 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | CHEMBL2177249 |
---|---|
Molecular formula | C23H26O4 |
IUPAC name | 5-methoxy-3-[(3-methoxyphenyl)methyl]-7-pentylchromen-2-one |
Molecular weight | 366.457 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 0 |
XlogP | 6.2 |
Synonyms | BDBM50398237 |
Inchi Key | FUDLPNVYTSNVGM-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C23H26O4/c1-4-5-6-8-17-13-21(26-3)20-15-18(23(24)27-22(20)14-17)11-16-9-7-10-19(12-16)25-2/h7,9-10,12-15H,4-6,8,11H2,1-3H3 |
PubChem CID | 70677677 |
ChEMBL | CHEMBL2177249 |
IUPHAR | N/A |
BindingDB | 50398237 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 3230.0 nM | PMID23679955 | BindingDB,ChEMBL |
Kb | 16500.0 nM | PMID23679955 | ChEMBL |
Kd | 0.00794 nM | PMID23679955 | BindingDB |
Kd | 0.007943 nM | PMID23679955 | ChEMBL |
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