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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL156369
Molecular formula	C19H21ClN4
IUPAC name	3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-4-methylpyrazolo[1,5-a]pyridine
Molecular weight	340.855
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.5
Synonyms	3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-pyrazolo[1,5-a]pyridine 3-[4-(4-Chlorophenyl)piperazinomethyl]-4-methylpyrazolo[1,5-a]pyridine BDBM50109953 4-(4-Chloro-phenyl)-1-(4-methyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium
Inchi Key	FVQOIDZBAPLYGQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21ClN4/c1-15-3-2-8-24-19(15)16(13-21-24)14-22-9-11-23(12-10-22)18-6-4-17(20)5-7-18/h2-8,13H,9-12,14H2,1H3
PubChem CID	44270444
ChEMBL	CHEMBL156369
IUPHAR	N/A
BindingDB	50109953
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	7000.0 nM	PMID11844688	BindingDB,ChEMBL

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