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GPCR

NameD(1A) dopamine receptor
SpeciesBos taurus (Bovine)
GeneDRD1
SynonymDopamine D1 receptor
DiseaseN/A for non-human GPCRs
Length446
Amino acid sequenceMRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProtQ95136
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2967
IUPHARN/A
DrugBankN/A

Ligand

Name3-(3,4-Dimethylphenyl)-1-propyl-piperidine hydrochloride
Molecular formulaC16H26ClN
IUPAC name3-(3,4-dimethylphenyl)-1-propylpiperidine;hydrochloride
Molecular weight267.841
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogPNone
Synonyms219704-16-2
CHEMBL554818
3-(3,4-dimethylphenyl)-1-propylpiperidine hydrochloride
CTK8E4167
KB-232859
[ Show all ]
Inchi KeyFYCADJCOSUMNIA-UHFFFAOYSA-N
Inchi IDInChI=1S/C16H25N.ClH/c1-4-9-17-10-5-6-16(12-17)15-8-7-13(2)14(3)11-15;/h7-8,11,16H,4-6,9-10,12H2,1-3H3;1H
PubChem CID45264409
ChEMBLCHEMBL554818
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
Ki<10000.0 nMPMID12502370ChEMBL

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