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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 2A
SpeciesCanis lupus familiaris (Dog)
GeneHTR2A
Synonym5-HT-2
5-HT-2A
5-hydroxytryptamine receptor
Serotonin receptor 2A
DiseaseN/A for non-human GPCRs
Length470
Amino acid sequenceMDVLFEDNAPLSPTTSSLMPSNGDPRLYGNDLNAGDANTSDAFNWTVDAENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDIIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKKDAKSTDNDYSMVALGKQHSEDAPTDNINTVNEKVSCV
UniProtO46635
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5781
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 7
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GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
144452D structureCHEMBL3286560C16H19N3O269.3484 / 12.4Yes
285082D structureCHEMBL576631C17H19N5293.3744 / 12.8Yes
547342D structure2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepineC15H17N3239.3223 / 12.1Yes
2776232D structureCHEMBL565547C17H19N5293.3744 / 12.4Yes
2868812D structureCHEMBL1214946C17H18ClFN4O2364.8055 / 02.0Yes
3557172D structureCHEMBL3286561C16H20N4268.3644 / 22.4Yes
4383232D structureCHEMBL492301C21H25ClN2O3S420.9525 / 13.8Yes

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