Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	C-C chemokine receptor type 3
Species	Rattus norvegicus (Rat)
Gene	Ccr3
Synonym	CKR3 chemokine (C-C motif) receptor 3 CD193 CCR3 CCR-3 CC-CKR-3 CC CKR3 C-C CKR-3 MIP-1alphaRL-2 (mouse) [ Show all ]
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MASNEEELKTVVETFETTPYEYEWAPPCEKVSIRELGSWLLPPLYSLVFIVGLLGNMMVVLILIKYRKLQIMTNIYLLNLAISDLLFLFTVPFWIHYVLWNEWGFGHCMCKMLSGLYYLALYSEIFFIILLTIDRYLAIVHAVLALRARTVTFATITSIITWGFAVLAALPEFIFHESQDNFGDLSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIQLIFVVMIVFFIFWTPYNLVLLLSAFHSTFLETSCQQSIHLDLAMQVTEVITHTHCCINPIIYAFVGERFRKHLRLFFHRNVAIYLRKYISFLPGEKLERTSSVSPSTGEQEISVVF
UniProt	O54814
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3928
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
26129	CHEMBL178447	C28H31Cl2N3O2	512.475	4 / 1	5.4	No
443624	CHEMBL3355937	C25H30FN3OS	439.593	4 / 2	5.0	Yes
443639	CHEMBL3355965	C34H38Cl2FN5O3	654.608	6 / 3	4.8	No
444379	CHEMBL3355939	C23H26F2N2OS	416.531	5 / 2	4.5	Yes
113228	CHEMBL363840	C28H36FN7O	505.642	6 / 2	4.8	No
446571	CHEMBL3355932	C24H28F2N2S	414.559	4 / 1	6.2	No
447204	CHEMBL3355940	C25H30F2N2OS	444.585	5 / 1	5.5	No
447312	CHEMBL3355943	C23H27FN2OS	398.54	4 / 2	4.4	Yes
447512	CHEMBL3355933	C24H29FN2S	396.568	3 / 1	6.1	No
447917	CHEMBL3355958	C33H36F2N2O2S	562.72	6 / 0	8.1	No
448757	CHEMBL3355964	C28H35Cl2FN4O	533.513	3 / 3	6.7	No
448831	CHEMBL3355944	C25H31FN2OS	426.594	4 / 1	5.4	No
449031	CHEMBL3355966	C35H40Cl2FN5O3	668.635	6 / 2	7.4	No
449317	CHEMBL3355947	C25H31FN2OS	426.594	4 / 1	6.1	No
449725	CHEMBL3355961	C32H35F2N3O2S	563.708	7 / 0	7.7	No
450005	CHEMBL3355952	C26H30F2N2O2S	472.595	6 / 1	3.6	Yes
221020	CHEMBL195433	C26H35FN4O2S	486.65	6 / 2	5.3	No
451613	CHEMBL3355962	C30H31F2N3O2S	535.654	7 / 1	4.3	No
451623	CHEMBL3355938	C23H26F2N2S	400.532	4 / 1	5.8	No
451845	CHEMBL3355934	C25H31FN2S	410.595	3 / 1	6.5	No
452975	CHEMBL3355954	C31H32F2N6S	558.696	7 / 1	7.0	No
453030	CHEMBL3355935	C24H29FN2OS	412.567	4 / 2	5.8	No
453097	CHEMBL3355953	C31H32F2N2O2S	534.666	6 / 1	5.1	No
453534	CHEMBL3355960	C30H31F2N3O2S	535.654	7 / 1	4.7	No
453780	CHEMBL3355946	C24H29FN2OS	412.567	4 / 2	5.8	No
454751	CHEMBL3355945	C25H31FN2S	410.595	3 / 1	6.5	No
455802	CHEMBL3355936	C25H31FN2OS	426.594	4 / 1	6.1	No
455867	CHEMBL3355963	C32H35F2N3O2S	563.708	7 / 0	7.3	No
456388	CHEMBL3355959	C32H35F2N3O2S	563.708	7 / 0	7.3	No
458103	CHEMBL3355949	C25H29FN2O2S	440.577	5 / 2	3.4	Yes
458324	CHEMBL3355956	C30H31F2N3O2S	535.654	7 / 1	4.3	No
458388	CHEMBL3355951	C30H32F2N2S	490.657	4 / 0	7.8	No
458570	CHEMBL3355941	C25H28F2N2O2S	458.568	6 / 1	5.9	No
458955	CHEMBL3355955	C32H34F2N2O2S	548.693	6 / 1	5.0	No