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I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameGamma-aminobutyric acid type B receptor subunit 2
SpeciesHomo sapiens (Human)
GeneGABBR2
SynonymHG20
GPRC3B
GPR51
Gb2
gamma-aminobutyric acid (GABA) B receptor, 2
[ Show all ]
DiseasePain
Drug abuse
Fragile X syndrome
Nicotine dependence
Partial seizures
[ Show all ]
Length941
Amino acid sequenceMASPRSSGQPGPPPPPPPPPARLLLLLLLPLLLPLAPGAWGWARGAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILNLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
UniProtO75899
Protein Data Bank4mr7, 4mr8
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 4mr7.
BioLiPBL0264360, BL0264364, BL0264363, BL0264362, BL0264361
Therapeutic Target DatabaseT42446
ChEMBLN/A
IUPHARN/A
DrugBankBE0002340

Known ligands

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Total entries: 6
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5482592D structure4-aminobutyric acidC4H9NO2103.1213 / 2-3.2Yes
5499382D structureArbaclofen placarbilC19H26ClNO6399.8686 / 24.2Yes
5500912D structure(R)-BaclofenC10H12ClNO2213.6613 / 2-1.0Yes
1752562D structurebaclofenC10H12ClNO2213.6613 / 2-1.0Yes
5509182D structureCgp-36742C7H18NO2P179.23 / 2-2.7Yes
5520852D structuregabapentinC9H17NO2171.243 / 2-1.1Yes

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