You can:
| Name | 5-hydroxytryptamine receptor 2C |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Htr2c |
| Synonym | 5-HT-1C serotonin 1c receptor HTR1C 5-hydroxytryptamine receptor 1C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 460 |
| Amino acid sequence | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV |
| UniProt | P08909 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL324 |
| IUPHAR | 8 |
| DrugBank | BE0004882 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 87 |  Eticlopride | C17H25ClN2O3 | 340.848 | 4 / 2 | 3.1 | Yes |
| 259 |  CHEMBL109589 | C20H27NO | 297.442 | 2 / 1 | 5.1 | No |
| 521458 |  CHEMBL3818128 | C19H23ClFN | 319.848 | 2 / 1 | N/A | N/A |
| 782 |  4-(4-Fluorobenzoyl)piperidine | C12H14FNO | 207.248 | 3 / 1 | 1.7 | Yes |
| 848 |  4-Benzylpiperidine | C12H17N | 175.275 | 1 / 1 | 2.5 | Yes |
| 1472 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 2193 |  CHEMBL309992 | C22H26N4O4 | 410.474 | 6 / 1 | 3.1 | Yes |
| 3153 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 3599 |  2-Phenylcyclopropanamine | C9H11N | 133.194 | 1 / 1 | 1.5 | Yes |
| 3652 |  CHEMBL269396 | C21H22ClN | 323.864 | 1 / 0 | 6.1 | No |
| 521559 |  CHEMBL3764080 | C20H24N4O3 | 368.437 | 6 / 1 | 1.3 | Yes |
| 4467 |  CHEMBL211309 | C13H19NO3 | 237.299 | 4 / 1 | 1.3 | Yes |
| 521576 |  CHEMBL3765273 | C19H23ClN4O | 358.87 | 4 / 1 | 2.7 | Yes |
| 5008 |  CHEMBL130585 | C21H23N3O3 | 365.433 | 4 / 0 | 3.8 | Yes |
| 5314 |  CHEMBL2260621 | C17H17NO3S | 315.387 | 5 / 1 | 3.5 | Yes |
| 5771 |  paroxetine | C19H20FNO3 | 329.371 | 5 / 1 | 3.5 | Yes |
| 6267 |  CHEMBL76237 | C19H22N2O3S | 358.456 | 4 / 0 | 3.5 | Yes |
| 6870 |  CHEMBL13632 | C17H17BrClNO | 366.683 | 2 / 1 | 4.7 | Yes |
| 7246 |  CHEMBL426813 | C21H24ClN3O3 | 401.891 | 5 / 0 | 2.6 | Yes |
| 8026 |  CHEMBL105152 | C19H25NO | 283.415 | 2 / 1 | 4.4 | Yes |
| 8158 |  CHEMBL3261700 | C28H29N3O2 | 439.559 | 3 / 2 | 5.6 | No |
| 8216 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 10363 |  CHEMBL6426 | C11H11BrN2 | 251.127 | 1 / 2 | 2.2 | Yes |
| 11055 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11181 |  ISOCLOZAPINE | C18H19ClN4 | 326.828 | 3 / 1 | 3.1 | Yes |
| 11221 |  CHEMBL61207 | C17H21BrN2O2 | 365.271 | 4 / 2 | 3.5 | Yes |
| 11714 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12458 |  CHEMBL338696 | C22H25FN2O | 352.453 | 3 / 1 | 3.6 | Yes |
| 12608 |  CHEMBL148128 | C14H20FNO | 237.318 | 3 / 1 | 2.3 | Yes |
| 13677 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 14011 |  CHEMBL102268 | C20H27NO2 | 313.441 | 3 / 1 | 4.4 | Yes |
| 14118 |  CHEMBL2260619 | C17H17NO2S | 299.388 | 4 / 0 | 4.6 | Yes |
| 14506 |  CHEMBL119323 | C13H16BrNO2 | 298.18 | 3 / 1 | 2.0 | Yes |
| 14508 |  CHEMBL331864 | C13H16BrNO2 | 298.18 | 3 / 1 | 2.0 | Yes |
| 15846 |  CHEMBL565707 | C25H31N3O4 | 437.54 | 6 / 1 | 4.5 | Yes |
| 16038 |  ISOLOXAPINE | C18H18ClN3O | 327.812 | 3 / 0 | 3.1 | Yes |
| 16887 |  Glemanserin | C20H25NO | 295.426 | 2 / 1 | 3.8 | Yes |
| 18321 |  CHEMBL357870 | C16H14N4O | 278.315 | 2 / 2 | 1.8 | Yes |
| 20189 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 20405 |  CHEMBL338095 | C21H22ClFN2O | 372.868 | 3 / 0 | 4.7 | Yes |
| 522066 |  CHEMBL3763812 | C18H21FN4O | 328.391 | 5 / 1 | 1.9 | Yes |
| 522073 |  CHEMBL3765471 | C25H27ClF2N4O | 472.965 | 6 / 2 | N/A | N/A |
| 21607 |  CHEMBL543964 | C16H16ClN3O | 301.774 | 1 / 3 | N/A | N/A |
| 21668 |  CHEMBL310940 | C22H27N3O | 349.478 | 4 / 0 | 3.7 | Yes |
| 21854 |  CHEMBL126737 | C21H22ClFN2O | 372.868 | 3 / 0 | 4.7 | Yes |
| 22310 |  CHEMBL319998 | C15H18N2O | 242.322 | 2 / 1 | 1.7 | Yes |
| 22630 |  CHEMBL94067 | C24H25N | 327.471 | 1 / 0 | 5.1 | No |
| 22981 |  CHEMBL315790 | C19H21BrN2O | 373.294 | 3 / 0 | 4.5 | Yes |
| 23064 |  CHEMBL1744161 | C23H25N3O6 | 439.468 | 7 / 4 | N/A | N/A |
| 553351 |  [125I]DOI | C11H16INO2 | 319.159 | 3 / 1 | 2.5 | Yes |
| 23161 |  CHEMBL134519 | C11H16INO2 | 321.158 | 3 / 1 | 2.5 | Yes |
| 23166 |  1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | C11H16INO2 | 321.158 | 3 / 1 | 2.5 | Yes |
| 23248 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 23358 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 23850 |  CHEMBL6746 | C11H9BrN2 | 249.111 | 1 / 1 | 2.5 | Yes |
| 25098 |  SCHEMBL8959504 | C11H12ClFN2 | 226.679 | 2 / 1 | 2.2 | Yes |
| 25101 |  SCHEMBL8959894 | C11H12ClFN2 | 226.679 | 2 / 1 | 2.2 | Yes |
| 25131 |  CHEMBL329280 | C28H31FN6O | 486.595 | 4 / 1 | 3.4 | Yes |
| 25314 |  6-Methoxy-4,9-dihydro-3H-beta-carboline | C12H12N2O | 200.241 | 2 / 1 | 1.8 | Yes |
| 26066 |  S-(-)-Lisuride | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26580 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26984 |  CHEMBL108173 | C20H27NO2 | 313.441 | 3 / 1 | 4.4 | Yes |
| 27594 |  2-phenethyl-1H-benzo[d]imidazole | C15H14N2 | 222.291 | 1 / 1 | 3.5 | Yes |
| 28176 |  CHEMBL294902 | C17H19Br2NO2 | 429.152 | 3 / 1 | 4.8 | Yes |
| 28864 |  CHEMBL314459 | C16H23NO3 | 277.364 | 4 / 3 | 2.4 | Yes |
| 29418 |  CHEMBL1940420 | C18H22FN3O | 315.392 | 5 / 0 | 3.7 | Yes |
| 29757 |  CHEMBL111912 | C18H29NO | 275.436 | 2 / 1 | 5.3 | No |
| 30833 |  CHEMBL129230 | C22H23FN2O | 350.437 | 3 / 0 | 3.7 | Yes |
| 31879 |  CHEMBL556969 | C21H21NO | 303.405 | 2 / 0 | 4.1 | Yes |
| 32280 |  Clorgiline | C13H15Cl2NO | 272.169 | 2 / 0 | 4.2 | Yes |
| 32652 |  CHEMBL83658 | C19H22N2O | 294.398 | 3 / 0 | 3.9 | Yes |
| 33097 |  CHEMBL57939 | C17H19BrINO2 | 476.152 | 3 / 1 | 4.8 | Yes |
| 33142 |  CHEMBL110151 | C18H23NO | 269.388 | 2 / 1 | 4.0 | Yes |
| 33444 |  CHEMBL3261701 | C24H24Cl2N2O2 | 443.368 | 3 / 1 | 5.9 | No |
| 34072 |  CHEMBL318639 | C17H22N2O | 270.376 | 2 / 1 | 2.6 | Yes |
| 34261 |  CHEMBL2331807 | C14H16N2O2 | 244.294 | 3 / 1 | 1.3 | Yes |
| 34804 |  CHEMBL1202030 | C21H24FNO | 325.427 | 3 / 0 | 4.5 | Yes |
| 37754 |  CHEMBL148385 | C18H18N4O | 306.369 | 2 / 1 | 2.0 | Yes |
| 37837 |  CHEMBL327527 | C27H30FN7O | 487.583 | 5 / 1 | 3.2 | Yes |
| 522663 |  CHEMBL3754784 | C27H33ClN4O2S | 513.097 | 6 / 0 | 4.9 | No |
| 38398 |  4-Ethoxyamphetamine | C11H17NO | 179.263 | 2 / 1 | 2.1 | Yes |
| 38623 |  3-[2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one | C20H21F3N4O | 390.41 | 6 / 1 | 3.3 | Yes |
| 558457 |  CHEMBL70609 | C19H22N4O3S | 386.47 | 6 / 1 | 2.0 | Yes |
| 39056 |  CHEMBL126823 | C21H24N2O | 320.436 | 2 / 0 | 3.9 | Yes |
| 39545 |  CHEMBL313856 | C11H12ClFN2 | 226.679 | 2 / 1 | 2.2 | Yes |
| 40061 |  CHEMBL85507 | C20H25FN2O | 328.431 | 4 / 1 | 4.6 | Yes |
| 40307 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 40590 |  1-(2,6-dimethoxy-4-methylphenyl)propan-2-amine | C12H19NO2 | 209.289 | 3 / 1 | 2.0 | Yes |
| 40964 |  16502-01-5 | C11H12N2 | 172.231 | 1 / 2 | 1.5 | Yes |
| 522787 |  CHEMBL3764284 | C19H23ClN4O | 358.87 | 4 / 1 | 2.7 | Yes |
| 42735 |  CHEMBL79496 | C19H20N2O2 | 308.381 | 3 / 0 | 3.3 | Yes |
| 43154 |  64022-27-1 | C8H11ClN4 | 198.654 | 4 / 1 | 0.5 | Yes |
| 43345 |  CHEMBL318249 | C28H32FN7O | 501.61 | 5 / 1 | 3.2 | No |
| 43554 |  fluvoxamine | C15H21F3N2O2 | 318.34 | 7 / 1 | 2.6 | Yes |
| 44309 |  CHEMBL1202030 | C23H26FNO5 | 415.461 | 7 / 2 | N/A | N/A |
| 558648 |  CHEMBL2260626 | C16H14N2O | 250.301 | 2 / 2 | 3.9 | Yes |
| 44536 |  CHEMBL276031 | C19H26N2O | 298.43 | 2 / 1 | 3.9 | Yes |
| 44969 |  CHEMBL98299 | C27H30FN7O | 487.583 | 5 / 1 | 3.2 | Yes |
| 45143 |  CHEMBL445106 | C12H14BrNO2 | 284.153 | 3 / 1 | 1.9 | Yes |
| 522845 |  CHEMBL3765797 | C18H22N4O3 | 342.399 | 5 / 1 | 0.9 | Yes |
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