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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 1D
SpeciesCanis lupus familiaris (Dog)
GeneHTR1D
Synonym5-HT-1D
5-HT1D
Serotonin receptor 1D
DiseaseN/A for non-human GPCRs
Length377
Amino acid sequenceMSPPNQSLEGLLQEASNRSLNATETPEAWGPETLQALKISLALLLSIITMATALSNAFVLTTIFLTRKLHTPANYLIGSLAMTDLLVSILVMPISIAYTTTRTWSFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGRAAVMIATVWVISICISIPPLFWRQAKAQEDMSDCQVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYVAARNRILNPPSLYGKRFTTAQLITGSAGSSLCSLSPSLQEERSHAAGPPLFFNHVQVKLAEGVLERKRISAARERKATKTLGIILGAFIVCWLPFFVASLVLPICRASCWLHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQRVVHVRKAS
UniProtP11614
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 14
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
110712D structuretryptamineC10H12N2160.221 / 21.6Yes
266062D structureYohimbineC21H26N2O3354.454 / 22.9Yes
622332D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
864782D structure4'-AminopropiophenoneC9H11NO149.1932 / 11.7Yes
1593412D structure5-METHOXYTRYPTAMINEC11H14N2O190.2462 / 20.5Yes
1711742D structure15532-75-9C11H13F3N2230.2345 / 12.3Yes
1748902D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
1756432D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
1766942D structureRU 24969C14H16N2O228.2952 / 21.8Yes
2903172D structureserotoninC10H12N2O176.2192 / 30.2Yes
3505492D structureLysergideC20H25N3O323.442 / 13.0Yes
3759572D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3882822D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No
4366242D structure5-Methoxy-N,N-dimethyltryptamineC13H18N2O218.32 / 11.5Yes

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