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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameD(1A) dopamine receptor
SpeciesRattus norvegicus (Rat)
GeneDrd1
SynonymGpcr15
D1 receptor
dopamine D1 receptor
DADR
D1A
[ Show all ]
DiseaseN/A for non-human GPCRs
Length446
Amino acid sequenceMAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
UniProtP18901
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL265
IUPHAR214
DrugBankN/A

Known ligands

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Total entries: 1373
Page:  / 14 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
852D structureEticloprideC17H25ClN2O3340.8484 / 23.1Yes
2912D structureCHEMBL1783352C24H26N6398.5145 / 13.5Yes
4032D structurediazepamC16H13ClN2O284.7432 / 03.0Yes
7422D structureCHEMBL367875C21H27N3OS369.5274 / 03.4Yes
13972D structureCHEMBL37661C22H27N305.4651 / 05.5No
13992D structureCHEMBL39483C22H27N305.4651 / 05.5No
16452D structureCHEMBL574111C13H18ClNO239.7432 / 23.4Yes
18102D structureCHEMBL180319C15H17N3S2303.4424 / 03.0Yes
31912D structureCHEMBL92896C21H24ClFN2O374.8844 / 13.5Yes
34172D structureCHEMBL135616C22H29BrN2O417.3913 / 14.8Yes
37532D structureCHEMBL1173017C29H39N5457.6665 / 05.2No
37752D structureCHEMBL332178C19H21NO279.3832 / 03.3Yes
45102D structureCHEMBL497604C24H26N4O2402.4985 / 14.0Yes
46192D structureCHEMBL95112C23H27FN2O2S414.5396 / 03.4Yes
49782D structureCHEMBL190525C26H29N5O3459.555 / 23.4Yes
54542D structureCHEMBL175226C19H24ClN3OS377.9314 / 02.8Yes
55502D structureCHEMBL57470C14H15NO3245.2784 / 41.8Yes
57132D structureCHEMBL517962C19H22N4OS354.4726 / 03.9Yes
57582D structureparoxetineC19H20FNO3329.3715 / 13.5Yes
68712D structureCHEMBL13632C17H17BrClNO366.6832 / 14.7Yes
68802D structureCHEMBL171519C14H15N3225.2952 / 21.5Yes
72442D structureCHEMBL426813C21H24ClN3O3401.8915 / 02.6Yes
73122D structureCHEMBL289557C16H24ClNO281.8242 / 14.7Yes
73142D structureCHEMBL543613C22H24ClFN2O2S434.9546 / 1N/AN/A
76922D structureCID 44581146C26H30N4O2430.5524 / 23.5Yes
78702D structureCHEMBL173658C15H16N4252.3214 / 21.1Yes
79642D structureCHEMBL1743798C18H17F2N285.3383 / 04.0Yes
81192D structureCHEMBL317333C26H24FN5425.5115 / 04.0Yes
81932D structureCHEMBL1743781C18H20BrNO346.2682 / 2N/AN/A
82052D structureBW-723C86C16H18N2OS286.3933 / 23.0Yes
91342D structureCHEMBL542167C19H24ClN301.8581 / 1N/AN/A
111792D structureISOCLOZAPINEC18H19ClN4326.8283 / 13.1Yes
113982D structureCHEMBL555427C19H25BrClNO2414.7683 / 3N/AN/A
118652D structureCHEMBL1743799C18H20BrNO2362.2673 / 3N/AN/A
118672D structureCHEMBL1743774C18H20BrNO2362.2673 / 3N/AN/A
124312D structureCHEMBL40949C21H26ClNO3375.8934 / 35.1No
124782D structureCHEMBL1743819C18H19NO2281.3553 / 23.1Yes
131952D structureCHEMBL72220C21H23ClN2338.8792 / 04.9Yes
136222D structureADTNC10H13NO2179.2193 / 31.4Yes
136872D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
136972D structureBDBM86280C17H18BrNO2348.243 / 33.2Yes
137452D structureCHEMBL111083C17H19NO253.3452 / 23.3Yes
144122D structureCHEMBL404240C20H23NO2309.4093 / 03.7Yes
150162D structureCHEMBL1744043C19H19NO277.3672 / 13.3Yes
150182D structureCHEMBL1788212C19H19NO277.3672 / 13.3Yes
154532D structureCHEMBL87717C23H24FNO2365.4484 / 04.0Yes
157292D structureCHEMBL303993C16H16ClNO273.762 / 13.8Yes
157312D structureCHEMBL293158C16H16ClNO273.762 / 13.8Yes
157362D structureCHEMBL57579C16H16ClNO273.762 / 13.8Yes
158932D structureCHEMBL290149C21H25NO2S355.4964 / 34.4Yes
160822D structureCHEMBL545477C18H21Cl2NO338.2722 / 2N/AN/A
162412D structureCHEMBL1172734C27H40N4420.6454 / 05.3No
164062D structureCHEMBL301003C19H21NO2295.3823 / 23.5Yes
164082D structureCHEMBL56100C19H21NO2295.3823 / 23.5Yes
167022D structureCHEMBL137637C22H29ClN2O372.9373 / 24.5Yes
167992D structurePipamperoneC21H30FN3O2375.4885 / 12.0Yes
180892D structureCHEMBL333836C18H16F3NO3S383.3857 / 03.8Yes
182202D structureCHEMBL139081C20H20BrNS386.3512 / 05.8No
193972D structureBDBM86461C15H13NO2S271.3344 / 32.2Yes
194052D structureCHEMBL155208C17H17NO2267.3283 / 13.0Yes
201732D structureimipramineC19H24N2280.4152 / 04.8Yes
5220652D structureCHEMBL3763812C18H21FN4O328.3915 / 11.9Yes
206162D structureCHEMBL192037C14H24N2220.361 / 02.9Yes
207612D structureCHEMBL67355C17H19N5293.3744 / 11.7Yes
5220722D structureCHEMBL3765471C25H27ClF2N4O472.9656 / 2N/AN/A
212332D structure(RS)-PPCCC24H29NO3379.54 / 13.5Yes
214162D structureCHEMBL137536C22H26F2N2356.4614 / 04.3Yes
215952D structureCHEMBL136468C22H26ClFN2372.9123 / 04.8Yes
216082D structureCHEMBL543964C16H16ClN3O301.7741 / 3N/AN/A
223212D structureCHEMBL363466C20H25NO2311.4253 / 04.2Yes
225422D structureCHEMBL283036C19H19F3N4360.3846 / 13.6Yes
228942D structureCHEMBL85879C20H26N2294.4422 / 04.5Yes
232272D structureCHEMBL43345C17H17NO2267.3283 / 32.5Yes
232372D structureDIHYDREXIDINEC17H17NO2267.3283 / 32.5Yes
232502D structureDIHYDREXIDINEC17H17NO2267.3283 / 32.5Yes
5533602D structureDIHYDREXIDINEC17H17NO2267.3283 / 32.5Yes
233302D structure(+)-sulpirideC15H23N3O4S341.4266 / 20.6Yes
233462D structureLevosulpirideC15H23N3O4S341.4266 / 20.6Yes
233482D structuresulpirideC15H23N3O4S341.4266 / 20.6Yes
244772D structureCHEMBL257747C19H21NO3311.3814 / 13.1Yes
247682D structureSCHEMBL910344C20H23NO3325.4084 / 03.3Yes
250122D structureCHEMBL2425377C18H17NO3295.3384 / 12.8Yes
251462D structureCHEMBL340641C24H26Cl2N4O457.3994 / 15.3No
254992D structureCHEMBL401690C20H22INO4467.3035 / 13.7Yes
257902D structureNotopterolC21H22O5354.4025 / 14.5Yes
282652D structureCHEMBL276013C28H43N5O2481.6854 / 24.4Yes
284542D structureCHEMBL362060C18H19N3OS325.434 / 02.7Yes
286862D structure4-hydroxydinapsoline hydrobromideC16H15NO3269.34 / 41.7Yes
287592D structureCHEMBL307717C20H22F2N2328.4074 / 03.6Yes
288582D structureCHEMBL100572C16H23NO3277.3644 / 32.4Yes
288602D structureCHEMBL314459C16H23NO3277.3644 / 32.4Yes
301672D structureCHEMBL545240C8H10FNO155.1723 / 2-0.5Yes
311442D structureCHEMBL566522C19H19FN6350.4015 / 12.9Yes
317172D structureCHEMBL2112388C10H12N2O2192.2183 / 2-0.1Yes
320592D structureCHEMBL349311C20H22BrNO2388.3053 / 04.9Yes
322282D structure4-aminobutyric acidC4H9NO2103.1213 / 2-3.2Yes
323082D structureCHEMBL330274C19H21NO2295.3823 / 23.2Yes
323112D structuren-PropylapomorphineC19H21NO2295.3823 / 23.2Yes
324282D structureCHEMBL41809C20H25NO2S343.4854 / 34.2Yes
333042D structureBDBM50265778C26H30N4O2430.5524 / 23.1Yes

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