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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameThyrotropin-releasing hormone receptor
SpeciesMus musculus (Mouse)
GeneTrhr
SynonymTRH receptor
Thyroliberin receptor
TRH1 receptor
TRH-R
TRH-R1
DiseaseN/A for non-human GPCRs
Length393
Amino acid sequenceMENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELEDITVTDTYVSTTKVSFDDTCLASEN
UniProtP21761
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2467
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 53
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5217032D structureCHEMBL3780191C19H26I2N6O4656.2645 / 3-0.3No
5218372D structureCHEMBL3780248C23H27ClN6O4486.9575 / 30.7Yes
155912D structureCHEMBL607173C21H26N4O4398.4634 / 20.1Yes
155922D structureBDBM50050529C21H26N4O4398.4634 / 20.1Yes
5219252D structureCHEMBL3781522C17H23ClN6O4410.8595 / 3-1.2Yes
4677042D structureCHEMBL3600445C23H23I2N7O3699.2926 / 21.5No
4702922D structureCHEMBL3601786C18H21I2N7O3637.2216 / 20.2No
5237772D structureCHEMBL3782037C18H25IN6O4516.345 / 3-1.2No
5244622D structureCHEMBL3781773C23H27IN6O4578.4115 / 30.4No
5245352D structureCHEMBL3780836C16H20Cl2N6O4431.2745 / 4-0.5Yes
5245812D structureCHEMBL3780549C23H26I2N6O4704.3085 / 30.5No
4793192D structureCHEMBL3600448C19H26N8O3414.477 / 4-0.1Yes
5254802D structureCHEMBL3779931C18H25BrN6O4469.345 / 3-0.8Yes
1437582D structurePyr3TRHC17H23N5O4361.4025 / 3-2.1Yes
4812062D structureCHEMBL3601781C17H20BrN7O3450.2976 / 30.0Yes
1558062D structureCHEMBL180789C20H18ClN3O3383.8324 / 15.2No
4823572D structureCHEMBL3601782C16H19BrN8O3451.2857 / 4-0.2Yes
4830952D structureCHEMBL3601785C17H20BrN7O3450.2976 / 2-0.5Yes
1871222D structureCHEMBL2370383C19H30N4O4378.4734 / 30.5Yes
5273652D structureCHEMBL3781024C23H27BrN6O4531.4115 / 30.7No
4883022D structureCHEMBL3600444C24H25I2N7O3713.3196 / 21.9No
5275482D structureCHEMBL3780633C17H22I2N6O4628.215 / 3-1.1No
5277552D structureCHEMBL3780802C18H24I2N6O4642.2375 / 3-0.8No
4913262D structureCHEMBL3600447C20H27N7O3413.4826 / 30.1Yes
5284302D structureCHEMBL3780645C17H23IN6O4502.3135 / 3-1.5No
4945912D structureCHEMBL3601784C16H17I2N7O3609.1676 / 3-0.1No
2601812D structureCHEMBL360939C20H19ClN2O338.8352 / 15.0Yes
2774232D structureCHEMBL181006C20H19N3O3349.394 / 14.5Yes
2787762D structureCHEMBL359845C20H19N3O3349.394 / 14.5Yes
2917092D structurePK 11195C21H21ClN2O352.8622 / 05.5No
3007172D structureCHEMBL180456C17H13ClN2O296.7542 / 14.0Yes
5003312D structureCHEMBL3600452C16H18BrN7O3436.276 / 3-0.4Yes
3107062D structureCHEMBL179883C18H15ClN2O310.7812 / 14.4Yes
3128412D structureCHEMBL39363C17H24N6O4376.4175 / 3-2.2Yes
5016172D structureCHEMBL3600451C16H18ClN7O3391.8166 / 3-0.5Yes
3162162D structureCHEMBL180833C19H17ClN2O324.8082 / 14.9Yes
3369912D structureCHEMBL107238C22H30N4O4414.5064 / 20.9Yes
3369922D structureCHEMBL319910C22H30N4O4414.5064 / 20.9Yes
5049812D structureCHEMBL3600446C19H25N7O3399.4556 / 3-0.3Yes
3562562D structureCHEMBL179860C21H21ClN2O352.8622 / 05.4No
3608222D structureCHEMBL181118C20H19N3O3349.394 / 14.5Yes
5317162D structureCHEMBL3780373C19H27BrN6O4483.3675 / 3-0.3Yes
5317242D structureCHEMBL3781873C16H20I2N6O4614.1835 / 4-1.1No
5102062D structureCHEMBL3600453C16H17Br2N7O3515.1666 / 30.6No
3966022D structureprotirelinC16H22N6O4362.395 / 4-2.5Yes
3966052D structureThyrotropin releasing hormoneC16H22N6O4362.395 / 4-2.5Yes
5329082D structureCHEMBL3780746C17H23BrN6O4455.3135 / 3-1.1Yes
4034472D structureCHEMBL179861C20H19ClN2O338.8352 / 15.3No
5127582D structureCHEMBL3601783C16H18Br2N8O3530.1817 / 40.8No
5143122D structureCHEMBL3600450C20H32N6O3404.5155 / 40.3Yes
5148652D structureCHEMBL3600449C20H32N6O3404.5155 / 40.4Yes
4266002D structurePyroglutamyl-phenylalanyl-prolinamideC19H24N4O4372.4254 / 3-0.6Yes
5170702D structureCHEMBL3600454C17H19Br2N7O3529.1936 / 31.0No

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