Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

GPCR

NameFollicle-stimulating hormone receptor
SpeciesHomo sapiens (Human)
GeneFSHR
SynonymFollitropin receptor
FSH receptor
FSH-R
LGR1
DiseaseContraception
Female infertility
Ovarian cancer
African trypanosomiasis
Length695
Amino acid sequenceMALLLVSLLAFLSLGSGCHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIHSLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSYGLENLKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSILRQEVDYMTQARGQRSSLAEDNESSYSRGFDMTYTEFDYDLCNEVVDVTCSPKPDAFNPCEDIMGYNILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCKVQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSSTVHNTHPRNGHCSSAPRVTNGSTYILVPLSHLAQN
UniProtP23945
Protein Data Bank4mqw
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 4mqw.
BioLiPBL0274372
Therapeutic Target DatabaseT68334
ChEMBLCHEMBL2024
IUPHARN/A
DrugBankBE0000387

Known ligands

You can:

Total entries: 115
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
21322D structureCHEMBL300022C29H39N3O6525.6466 / 14.3No
5215712D structureCHEMBL3809148C32H36FN5O3557.676 / 24.1No
120402D structureCHEMBL3263685C31H31N5O4537.626 / 33.9No
147992D structureCHEMBL192135C33H32N2O2488.6312 / 16.8No
160632D structureCHEMBL3263663C31H37N5O4543.6686 / 23.8No
204012D structureCHEMBL436481C34H34N2O2502.6582 / 17.1No
211212D structureCHEMBL370917C28H31NO2413.5612 / 06.2No
290832D structureCHEMBL363164C33H32N2O3504.633 / 26.4No
330032D structureCHEMBL3263667C32H38N6O4570.6947 / 23.4No
434232D structureCHEMBL279759C29H40N2O5496.6485 / 05.9No
497172D structureCHEMBL3263673C31H36N6O3540.6686 / 23.0No
509412D structureCHEMBL3263664C31H37N5O4543.6686 / 23.8No
573842D structureCHEMBL1651828C29H38N12O4S2682.82314 / 43.7No
574692D structureCHEMBL47059C34H49N3O3547.7843 / 07.0No
5233072D structureCHEMBL3808949C30H36N6O4544.6566 / 43.7No
632452D structureCHEMBL3263666C30H36N6O4544.6567 / 23.2No
641172D structureCHEMBL46216C32H45N3O4535.7294 / 05.7No
697772D structureCHEMBL3263662C29H35N5O5S565.6898 / 23.1No
701382D structureCHEMBL3263676C32H38N6O4570.6947 / 23.4No
5200312D structureBDBM50142655C32H45N5O4563.7434 / 35.0No
788732D structuresuraminC51H40N6O23S61297.2623 / 121.5No
898722D structureCHEMBL179505C26H34N2O3422.5693 / 14.3Yes
917532D structureCHEMBL417003C29H40N2O3464.653 / 06.8No
923582D structureCHEMBL3263684C25H29N5O3447.5396 / 32.6Yes
959702D structureCHEMBL3263687C30H36N4O4516.6426 / 24.5No
1016822D structureCHEMBL372649C33H33NO2475.6322 / 07.4No
1055582D structureCHEMBL360981C30H34N2O2454.6142 / 16.5No
1098902D structureCHEMBL3263688C33H36N6O3564.697 / 24.7No
5247982D structureCHEMBL3263694C30H35N5O4529.6416 / 23.4No
1185982D structureCHEMBL45782C28H38N2O4466.6224 / 06.0No
1199262D structureCHEMBL3263693C32H40N6O3556.7117 / 23.5No
1208842D structureCHEMBL47500C28H38N2O5482.6215 / 05.3No
1219182D structureCHEMBL1651822C67H76N14O8S21269.5618 / 58.4No
1219202D structureCHEMBL1651825C67H76N14O8S21269.5618 / 58.4No
1287292D structureCHEMBL371595C27H30N2O3S462.6084 / 14.7Yes
1342602D structureCHEMBL43789C28H37N3O6511.6196 / 24.1No
1394062D structureCHEMBL3263678C28H32N6O4516.6027 / 22.3No
1403232D structureCHEMBL3263671C31H36N6O3540.6686 / 23.3No
1452222D structureCHEMBL433263C34H49N3O4563.7834 / 07.4No
1461522D structureCHEMBL361167C25H26N2O3402.4943 / 14.5Yes
1496542D structureCHEMBL3263681C33H40N6O4584.7217 / 23.8No
1632742D structureCHEMBL298686C28H38N2O5482.6215 / 05.5No
1650712D structureCHEMBL50556C36H44ClN5O4646.2294 / 35.5No
1704382D structureCHEMBL295895C34H50N4O3562.7993 / 16.9No
1715662D structureCHEMBL49308C30H42N2O5510.6755 / 06.4No
1715672D structureCHEMBL49624C30H42N2O5510.6755 / 06.4No
1715682D structureCHEMBL49540C30H42N2O5510.6755 / 06.4No
1715692D structureCHEMBL296449C30H42N2O5510.6755 / 06.4No
1794812D structureN-Isobutyl-2,4,8,10,12-tetradecapentaenamideC18H27NO273.421 / 14.9Yes
1861142D structureCHEMBL3263682C32H37N5O4555.6796 / 13.8No
1892952D structureCHEMBL3263691C29H33N9O3555.6439 / 33.3No
1916412D structureCHEMBL3263661C31H37N5O4543.6686 / 13.6No
1933992D structureCHEMBL1651821C65H72N14O7S21225.517 / 58.5No
1934002D structureCHEMBL1651824C65H72N14O7S21225.517 / 58.5No
1949912D structureCHEMBL195321C30H34N2O3470.6133 / 15.5No
1957942D structureCHEMBL3263670C32H37N5O3539.685 / 24.0No
1961082D structureCHEMBL49608C32H46N4O3534.7453 / 15.8No
2029672D structureCHEMBL3263660C30H35N5O4529.6416 / 23.1No
2059662D structureCHEMBL3263665C31H38N6O3542.6845 / 23.3No
2067622D structureCHEMBL1651831C69H80N14O9S21313.6119 / 58.2No
2067642D structureCHEMBL1651826C69H80N14O9S21313.6119 / 58.2No
2178162D structureCHEMBL192868C34H34N2O3518.6573 / 16.7No
2220192D structureCHEMBL3263686C30H36N4O3500.6435 / 26.1No
2294422D structureCHEMBL372506C27H29N3O2427.5482 / 24.9Yes
2373422D structureCHEMBL1651721C23H26N6O2S2482.6218 / 44.0Yes
2427852D structureCID 44292945C32H45N5O4563.7434 / 25.0No
2434892D structureCHEMBL300634C27H36N2O5468.5945 / 04.9Yes
2434902D structureCHEMBL50278C27H36N2O5468.5945 / 04.9Yes
2447642D structureCHEMBL3263677C32H38N6O4570.6947 / 23.4No
2458512D structureCHEMBL1651723C61H64N14O5S21137.415 / 58.8No
2458532D structureCHEMBL1651829C61H64N14O5S21137.415 / 58.8No
2474382D structureCHEMBL1651827C42H46N8O5742.8819 / 16.6No
2508072D structureCHEMBL3263669C29H37N5O3503.6475 / 22.8No
2515952D structureCHEMBL192334C33H31NO3489.6153 / 07.3No
2572742D structureCHEMBL48375C32H45N3O4535.7294 / 06.4No
2593822D structureCHEMBL47120C31H43N3O4521.7024 / 15.1No
2668962D structureCHEMBL2216804C30H30N2O4S514.645 / 25.2No
2682222D structureCHEMBL44663C32H45N3O3519.733 / 06.0No
2788542D structureCHEMBL48030C32H46N4O4550.7444 / 15.6No
2819172D structureCHEMBL195347C34H34N2O2502.6582 / 17.1No
2856622D structureCHEMBL3263683C29H33N5O4515.6146 / 23.1No
2994432D structureCHEMBL365545C33H32N2O2488.6312 / 16.8No
3004342D structureCHEMBL45770C32H45N5O4563.7434 / 24.2No
5300162D structureCHEMBL3809644C31H37N5O4543.6687 / 34.1No
3048152D structureCHEMBL3263680C31H36N4O4528.6535 / 24.1No
3050152D structureCHEMBL195534C20H24N2O308.4252 / 13.6Yes
3162392D structureCHEMBL426824C34H34N2O3518.6573 / 16.7No
3162442D structureCHEMBL3263692C31H37N5O5559.6678 / 43.1No
3233142D structureCHEMBL524348C30H28ClN3O4S562.0815 / 24.4No
3354622D structureCHEMBL3263689C29H33N5O5531.6137 / 23.5No
3375012D structureCHEMBL3263679C23H29N5O4439.5166 / 30.8Yes
3471202D structureCHEMBL361847C28H27F3N2O2480.5315 / 16.0No
3475432D structureCHEMBL432883C26H34N2O5454.5675 / 04.4Yes
3505932D structureCHEMBL47420C28H38N2O4466.6224 / 06.0No
3517112D structureAC1MLESTC21H25N5O5S459.5218 / 32.3Yes
3552662D structureCHEMBL1651823C63H68N14O6S21181.4516 / 58.7No
3552682D structureCHEMBL1651830C63H68N14O6S21181.4516 / 58.7No
3557752D structureCHEMBL364094C26H28N2O2S432.5823 / 14.8Yes
3679912D structureCHEMBL45976C29H40N2O5496.6485 / 06.0No
3697902D structureCHEMBL1651722C36H34N2O3542.6793 / 16.8No

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218