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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameAdenosine receptor A2b
SpeciesRattus norvegicus (Rat)
GeneAdora2b
SynonymA2b
A2B receptor
A2BR
adenosine receptor A2b
DiseaseN/A for non-human GPCRs
Length332
Amino acid sequenceMQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
UniProtP29276
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2592
IUPHAR20
DrugBankN/A

Known ligands

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Total entries: 83
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5214702D structureCHEMBL3827623C26H36N6O3480.6136 / 03.9Yes
63822D structureN'-hydroxy-2,3-dihydro-1,4-benzodioxine-3-carboximidamideC9H10N2O3194.194 / 21.0Yes
67332D structureMRS 1754C26H26N6O4486.5326 / 24.9Yes
232392D structureDIHYDREXIDINEC17H17NO2267.3283 / 32.5Yes
265512D structureRauwolscineC21H26N2O3354.454 / 22.9Yes
266212D structureYohimbineC21H26N2O3354.454 / 22.9Yes
439862D structureCHEMBL51394C20H21N5O347.4225 / 22.5Yes
492572D structureCHEMBL513681C20H18N4O4S410.4485 / 22.3Yes
559472D structureL-249313C18H16N4O2320.3525 / 01.6Yes
5233352D structureCHEMBL3827201C29H42N6O3522.6946 / 05.0No
646672D structurePD-168077C20H22N4O334.4234 / 13.0Yes
708532D structureCHEMBL120055C23H28N4O2392.5034 / 22.8Yes
768272D structure8-Cyclopentyl-1,3-dipropylxanthineC16H24N4O2304.3943 / 14.0Yes
822472D structureCHEMBL52276C21H20F3N5O415.428 / 23.4Yes
879342D structureCHEMBL67110C17H17ClN4O2344.7993 / 02.4Yes
885262D structureCHEMBL67228C14H14N4O2270.2923 / 11.9Yes
901152D structureCHEMBL160581C26H28N4O2428.5364 / 23.7Yes
982412D structureclonidineC9H9Cl2N3230.0921 / 21.6Yes
987802D structureCHEMBL51829C19H20N6O348.416 / 21.5Yes
1119922D structureCHEMBL1791423C12H13N5O4291.2678 / 4-0.9Yes
1119992D structureCHEMBL606438C12H13N5O4291.2678 / 4-0.9Yes
1151052D structurePSB-601C25H28N6O4S508.5977 / 22.4No
1161242D structureCHEMBL48683C18H19N5OS353.4446 / 22.2Yes
1208222D structureIDAZOXANC11H12N2O2204.2293 / 10.7Yes
1210252D structureCHEMBL2113492C15H22N6O4350.3798 / 40.7Yes
1233382D structureCHEMBL304455C9H8N4O2204.1893 / 10.1Yes
1244192D structureCHEMBL104985C14H18ClN3O279.7684 / 03.4Yes
1288632D structureCHEMBL50950C21H23N5O361.4495 / 22.9Yes
1309532D structureCHEMBL456125C26H27BrN4O5555.4295 / 34.6No
1431812D structure1-PropylxanthineC8H10N4O2194.1943 / 20.6Yes
1457802D structureNECAC12H16N6O4308.2988 / 4-0.7Yes
1462192D structureGR 103691C30H35N3O3485.6285 / 14.8Yes
5260522D structureCHEMBL3827187C28H42N6O3510.6836 / 04.9No
1624222D structureD0M5TMC12H10FN5243.2455 / 11.5Yes
1636912D structureCHEMBL299548C19H18FN5335.3865 / 13.9Yes
1669682D structureCHEMBL49925C21H20N6O372.4326 / 22.2Yes
5263872D structureCHEMBL3827598C26H38N6O3482.6296 / 04.2Yes
1757862D structureCHEMBL67060C11H15ClN4O2270.7173 / 00.8Yes
1802492D structureCHEMBL52432C14H17N5O271.3245 / 20.9Yes
1803742D structureCHEMBL297949C21H23N5O2377.4486 / 22.5Yes
1836852D structureCHEMBL2113489C16H22N6O4362.398 / 40.8Yes
1861342D structureCHEMBL51353C20H20ClN5O381.8645 / 23.1Yes
5269452D structureCHEMBL3827859C24H34N6O3454.5756 / 02.8Yes
1913882D structureN,N-di-n-propyldopamineC14H23NO2237.3433 / 21.8Yes
1928812D structureCHEMBL297685C19H18FN5O351.3856 / 22.1Yes
2066852D structureCHEMBL10873C15H14N4O2282.3033 / 12.8Yes
2106432D structure7-(3-Chloropropyl)theophyllineC10H13ClN4O2256.693 / 00.4Yes
2148252D structureCHEMBL48681C20H20FN5O365.4126 / 22.6Yes
2226092D structureCHEMBL308295C28H42N2O4470.6546 / 45.7No
2290572D structureCHEMBL51192C19H20FN5O353.4016 / 22.7Yes
2336142D structureCHEMBL51107C20H20ClN5O381.8645 / 23.1Yes
2407312D structureCHEMBL301512C20H20FN5O365.4126 / 22.6Yes
5544752D structureadenosineC10H13N5O4267.2458 / 4-1.1Yes
2471292D structureFK-453C23H25N3O2375.4723 / 13.2Yes
2480432D structureCHEMBL67313C15H16N4O2284.3193 / 12.3Yes
5288652D structureCHEMBL3827331C30H46N6O3538.7376 / 05.3No
2591152D structureCHEMBL50051C18H19N5O2337.3836 / 21.6Yes
2611272D structure8-PhenyltheophyllineC13H12N4O2256.2653 / 12.2Yes
2676482D structureCHEMBL48153C20H20FN5O365.4126 / 22.6Yes
2748312D structure7-(2-Chloroethyl)theophyllineC9H11ClN4O2242.6633 / 00.1Yes
2793372D structureCHEMBL307105C19H23ClN4O2374.8693 / 03.5Yes
3006302D structureCHEMBL332154C18H18N2O2294.3544 / 23.0Yes
3042592D structureCHEMBL170550C12H14N2O2218.2563 / 11.1Yes
5547892D structurecaffeineC8H10N4O2194.1943 / 0-0.1Yes
3118222D structureCHEMBL38465C14H13N3S255.3393 / 13.1Yes
3286682D structurefenoldopamC16H16ClNO3305.7584 / 42.4Yes
3428572D structureKF-17837C22H28N4O4412.495 / 03.6Yes
3451832D structureSch 58261C18H15N7O345.3666 / 12.4Yes
3471682D structureCHEMBL300624C17H16FN5O325.3476 / 21.6Yes
3616682D structureCHEMBL310997C28H40N2O4468.6386 / 45.3No
3616702D structureCHEMBL80974C28H40N2O4468.6386 / 45.3No
3616732D structureCHEMBL80686C28H40N2O4468.6386 / 45.3No
3671732D structuredopamineC8H11NO2153.1813 / 3-1.0Yes
3730732D structureCHEMBL296389C21H22FN5O379.4396 / 23.2Yes
3796362D structureCHEMBL37170C22H27N3O349.4783 / 13.5Yes
3796412D structureCHEMBL35093C22H27N3O349.4783 / 13.5Yes
4056042D structureCHEMBL355550C11H12N2O4236.2275 / 30.0Yes
4056742D structureCHEMBL63944C13H12N4O2256.2653 / 11.5Yes
4133482D structureCHEMBL50839C21H22FN5O2395.4387 / 22.6Yes
4275202D structuretheophyllineC7H8N4O2180.1673 / 10.0Yes
5335972D structureCHEMBL3827583C20H25N5O3383.4525 / 12.4Yes
4398852D structureCHEMBL96385C16H11N3O261.2842 / 12.8Yes
5338862D structureCHEMBL3827074C28H40N6O3508.6676 / 04.6No

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