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| Name | Adenosine receptor A2a |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Adora2a |
| Synonym | A2-AR A2A receptor adenosine receptor A2a RDC8 |
| Disease | N/A for non-human GPCRs |
| Length | 410 |
| Amino acid sequence | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS |
| UniProt | P30543 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL302 |
| IUPHAR | 19 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 71 |  Pyrimidin-4-ylacetamide, 26 | C19H24N6O2 | 368.441 | 6 / 1 | 2.0 | Yes |
| 521445 |  CHEMBL3735468 | C15H12ClN3O | 285.731 | 4 / 1 | 3.3 | Yes |
| 475 |  CHEMBL38304 | C28H32N6O4 | 516.602 | 6 / 2 | 3.2 | No |
| 533 |  CHEMBL338501 | C21H14Cl2N4 | 393.271 | 3 / 1 | 5.0 | Yes |
| 610 |  CHEMBL17202 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 614 |  CID 53633248 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 652 |  CHEMBL323403 | C24H23NO3S | 405.512 | 5 / 0 | 5.9 | No |
| 521469 |  CHEMBL3827623 | C26H36N6O3 | 480.613 | 6 / 0 | 3.9 | Yes |
| 899 |  CHEMBL72007 | C19H20N4O | 320.396 | 3 / 2 | 4.1 | Yes |
| 1043 |  Pyrimidin-4-ylacetamide, 9 | C20H24N6O3 | 396.451 | 7 / 1 | 1.7 | Yes |
| 1176 |  CHEMBL319971 | C17H14ClN5O2 | 355.782 | 5 / 1 | 3.2 | Yes |
| 1333 |  MRS-1042 | C24H28O5 | 396.483 | 5 / 0 | 6.0 | No |
| 1421 |  8-Phenylxanthine | C11H8N4O2 | 228.211 | 3 / 3 | 0.9 | Yes |
| 1576 |  CHEMBL366905 | C15H12N6O | 292.302 | 6 / 2 | 1.5 | Yes |
| 1897 |  CHEMBL368092 | C18H21N9O2 | 395.427 | 10 / 2 | 1.6 | Yes |
| 1931 |  2-(3-Cyclopentyl-1-propynyl)adenosine | C18H23N5O4 | 373.413 | 8 / 4 | 1.8 | Yes |
| 2023 |  CHEMBL180278 | C30H33N7O3 | 539.64 | 9 / 1 | 3.8 | No |
| 2180 |  CHEMBL343527 | C18H14N4O4 | 350.334 | 5 / 1 | 1.8 | Yes |
| 3105 |  Pyrimidin-4-ylacetamide, 6 | C22H29N7O2 | 423.521 | 7 / 1 | 2.2 | Yes |
| 3322 |  CHEMBL3093226 | C21H27N5O3 | 397.479 | 5 / 0 | 2.7 | Yes |
| 3433 |  CHEMBL2113345 | C17H18N4O4 | 342.355 | 5 / 3 | 1.8 | Yes |
| 3852 |  UNII-63K7WDR6RX | C20H19N7O2 | 388.419 | 7 / 1 | 2.7 | Yes |
| 3859 |  316173-57-6 | C20H19N7O2 | 389.419 | 7 / 1 | 2.7 | Yes |
| 4589 |  CHEMBL79201 | C14H14N6OS | 314.367 | 6 / 2 | 1.2 | Yes |
| 4754 |  CHEMBL27376 | C20H20ClIN6O3 | 554.773 | 7 / 4 | 2.0 | No |
| 5155 |  CHEMBL1095693 | C12H12N2OS | 232.301 | 3 / 0 | 1.8 | Yes |
| 5267 |  CHEMBL164039 | C24H29NO4S2 | 459.619 | 7 / 0 | 5.6 | No |
| 5371 |  CHEMBL3093315 | C17H17N5O2S | 355.416 | 5 / 0 | 1.4 | Yes |
| 5629 |  2-(1-hexynyl)adenosine | C16H21N5O4 | 347.375 | 8 / 4 | 1.3 | Yes |
| 5657 |  FR-166124 | C25H22N4O3 | 426.476 | 5 / 1 | 2.9 | Yes |
| 5800 |  CHEMBL392115 | C19H23N5O3 | 369.425 | 5 / 1 | 1.4 | Yes |
| 521631 |  CHEMBL3828530 | C20H26N6O3 | 398.467 | 6 / 0 | 1.7 | Yes |
| 5867 |  CHEMBL72287 | C22H16N2O | 324.383 | 3 / 0 | 4.0 | Yes |
| 6541 |  CHEMBL1092868 | C16H13N7O2S | 367.387 | 7 / 2 | 2.4 | Yes |
| 6643 |  CHEMBL27773 | C17H11BrN2O2 | 355.191 | 3 / 0 | 4.4 | Yes |
| 6720 |  CHEMBL608327 | C18H18ClIN6O4 | 544.734 | 8 / 4 | 1.5 | No |
| 6736 |  MRS 1754 | C26H26N6O4 | 486.532 | 6 / 2 | 4.9 | Yes |
| 6960 |  CHEMBL387319 | C18H23N7O2 | 369.429 | 8 / 2 | 1.1 | Yes |
| 6994 |  1,3-DibutylX-7-riboside | C18H35N5O4 | 385.509 | 8 / 4 | -0.3 | Yes |
| 7078 |  CHEMBL286479 | C17H12BrN3O2 | 370.206 | 4 / 1 | 3.7 | Yes |
| 7229 |  CHEMBL424433 | C15H20N4O4 | 320.349 | 5 / 0 | 0.9 | Yes |
| 7291 |  CID 71508724 | C15H23N7O8 | 429.39 | 14 / 9 | -2.7 | No |
| 7421 |  CHEMBL380914 | C19H19Cl2N7O5 | 496.305 | 8 / 5 | 1.3 | Yes |
| 7910 |  CHEMBL27502 | C17H23N5O2 | 329.404 | 6 / 3 | 1.5 | Yes |
| 8222 |  CHEMBL337503 | C30H31N2O5S+ | 531.647 | 6 / 0 | 5.4 | No |
| 8495 |  CHEMBL66811 | C24H19N7O2 | 437.463 | 7 / 1 | 3.6 | Yes |
| 8516 |  CHEMBL206807 | C22H27N7O6 | 485.501 | 9 / 5 | 0.6 | Yes |
| 8519 |  CHEMBL610394 | C22H27N7O6 | 485.501 | 9 / 5 | 0.6 | Yes |
| 8700 |  CHEMBL98278 | C20H21N7O4 | 423.433 | 9 / 4 | 0.5 | Yes |
| 8934 |  CHEMBL3291305 | C20H21N5O | 347.422 | 5 / 1 | 4.1 | Yes |
| 9035 |  CHEMBL184641 | C21H23F2N9O | 455.474 | 11 / 2 | 2.8 | No |
| 9037 |  CHEMBL318264 | C14H17N7O4 | 347.335 | 9 / 4 | -1.1 | Yes |
| 9129 |  172516-44-8 | C17H24O3S2 | 340.496 | 5 / 0 | 5.3 | No |
| 9249 |  CHEMBL168892 | C16H14BrN3O | 344.212 | 3 / 1 | 4.3 | Yes |
| 9277 |  CHEMBL363647 | C19H18N6O2 | 362.393 | 6 / 2 | 2.0 | Yes |
| 10016 |  CHEMBL223321 | C23H27ClF3N11O | 565.99 | 13 / 2 | 2.9 | No |
| 10153 |  CHEMBL2113426 | C19H23N5O3S | 401.485 | 8 / 3 | 2.3 | Yes |
| 459309 |  CHEMBL2158244 | C15H10FNO2S | 287.308 | 4 / 1 | 2.8 | Yes |
| 10226 |  CHEMBL413046 | C26H31N7O6 | 537.577 | 9 / 5 | 2.0 | No |
| 10308 |  CHEMBL177386 | C19H19Cl2N9O | 460.323 | 9 / 2 | 2.9 | Yes |
| 10340 |  CHEMBL609543 | C14H21N5O5 | 339.352 | 9 / 4 | -0.5 | Yes |
| 10652 |  CHEMBL315562 | C16H11FN8O | 350.317 | 8 / 1 | 2.3 | Yes |
| 10666 |  CHEMBL444281 | C25H27N5O5 | 477.521 | 6 / 3 | 4.8 | Yes |
| 11030 |  3-Isobutyl-1-methylxanthine | C10H14N4O2 | 222.248 | 3 / 1 | 1.5 | Yes |
| 11035 |  CHEMBL2113469 | C19H29N5O3S | 407.533 | 8 / 3 | 3.0 | Yes |
| 11136 |  CHEMBL163813 | C26H34ClNO3S | 476.072 | 5 / 0 | 8.2 | No |
| 11295 |  2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine | C9H8N6OS | 248.264 | 7 / 1 | 1.1 | Yes |
| 11352 |  CHEMBL606228 | C19H28N4O4 | 376.457 | 7 / 4 | 2.8 | Yes |
| 11439 |  CHEMBL2113704 | C16H15IN6 | 418.242 | 5 / 1 | 2.7 | Yes |
| 11518 |  CHEMBL2113685 | C16H18IN5O2S | 471.317 | 7 / 3 | 2.0 | Yes |
| 11626 |  CHEMBL475146 | C23H23N5O3 | 417.469 | 6 / 1 | 3.4 | Yes |
| 11995 |  5'-ChloroAdo | C9H10ClN5O3 | 271.661 | 7 / 3 | -0.2 | Yes |
| 12220 |  CHEMBL520297 | C24H25FN6O4S | 512.56 | 8 / 2 | 2.0 | No |
| 12231 |  CHEMBL337629 | C12H14O3S2 | 270.361 | 5 / 0 | 3.1 | Yes |
| 13179 |  CHEMBL2113493 | C10H12N6O6 | 312.242 | 10 / 4 | -0.9 | Yes |
| 13808 |  Arborinine | C16H15NO4 | 285.299 | 5 / 1 | 3.3 | Yes |
| 13834 |  (E)-8-(2,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine | C20H24N4O4 | 384.436 | 5 / 0 | 2.5 | Yes |
| 521866 |  CHEMBL3828002 | C24H33N5O3 | 439.56 | 5 / 1 | 4.2 | Yes |
| 13920 |  9-(3-chlorophenyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione | C16H16ClN5O2 | 345.787 | 4 / 0 | 2.3 | Yes |
| 14021 |  CHEMBL142962 | C20H20N4O | 332.407 | 4 / 1 | 3.8 | Yes |
| 14073 |  CHEMBL187810 | C21H25N9O | 419.493 | 9 / 2 | 2.6 | Yes |
| 14166 |  CHEMBL2113702 | C13H11ClIN5 | 399.62 | 4 / 1 | 3.5 | Yes |
| 14477 |  CHEMBL78317 | C23H30N4O3 | 410.518 | 4 / 0 | 4.4 | Yes |
| 14760 |  CHEMBL129406 | C16H14N2 | 234.302 | 2 / 0 | 3.6 | Yes |
| 14839 |  CHEMBL310097 | C22H21ClN4 | 376.888 | 3 / 1 | 5.3 | No |
| 14842 |  CHEMBL83863 | C22H21ClN4 | 376.888 | 3 / 1 | 5.3 | No |
| 15184 |  CHEMBL133103 | C15H16N6OS | 328.394 | 6 / 2 | 2.2 | Yes |
| 15519 |  CHEMBL337081 | C11H14N2O3S | 254.304 | 6 / 2 | 2.4 | Yes |
| 16356 |  CHEMBL2113547 | C17H24ClN5O4 | 397.86 | 8 / 3 | 1.4 | Yes |
| 16390 |  CHEMBL338723 | C17H19N5OS2 | 373.493 | 6 / 1 | 3.8 | Yes |
| 16471 |  CHEMBL187071 | C22H23F3N8O | 472.476 | 11 / 1 | 2.9 | No |
| 16589 |  CHEMBL67026 | C19H17N7O2 | 375.392 | 7 / 2 | 2.4 | Yes |
| 16640 |  BDBM110138 | C16H15BrN4O2 | 375.226 | 3 / 0 | 2.6 | Yes |
| 16653 |  CHEMBL3093310 | C19H19N5O2 | 349.394 | 4 / 0 | 1.7 | Yes |
| 16688 |  CHEMBL262924 | C29H30ClN7O3 | 560.055 | 9 / 1 | 4.1 | No |
| 16870 |  CHEMBL98828 | C24H27ClN6O4 | 498.968 | 7 / 2 | 4.0 | Yes |
| 16979 |  CHEMBL610992 | C19H29N5O5 | 407.471 | 9 / 4 | 2.7 | Yes |
| 17003 |  CHEMBL439141 | C16H20N8O | 340.391 | 8 / 1 | 1.5 | Yes |
| 17054 |  CHEMBL187366 | C19H17F3N8O | 430.395 | 11 / 1 | 2.3 | No |
| 17369 |  CHEMBL363660 | C22H24F2N8O | 454.486 | 10 / 1 | 2.8 | Yes |
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