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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 1F
SpeciesRattus norvegicus (Rat)
GeneHtr1f
SynonymHTR1EL
5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
5-HT6
5-HT1F receptor
5-HT1F
[ Show all ]
DiseaseN/A for non-human GPCRs
Length366
Amino acid sequenceMDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINCLVITAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQGLCDLWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGITITTVWVISVFISVPPLFWRHQGNSRDDQCIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVLLESGEKSIKLVSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNICEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRN
UniProtP30940
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4646
IUPHAR5
DrugBankN/A

Known ligands

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Total entries: 10
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
265762D structureYohimbineC21H26N2O3354.454 / 22.9Yes
1244132D structureCHEMBL104985C14H18ClN3O279.7684 / 03.4Yes
1748932D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
1756662D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
2445262D structureA-131701C24H24N4O3S448.5416 / 13.2Yes
2903232D structureserotoninC10H12N2O176.2192 / 30.2Yes
2990452D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3759712D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3861502D structuremetergolineC25H29N3O2403.5263 / 13.8Yes
3882862D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No

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