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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

Name5-hydroxytryptamine receptor 5A
SpeciesMus musculus (Mouse)
GeneHtr5a
SynonymMR22
Htr5
5HT5-
5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
5-HT5alpha
[ Show all ]
DiseaseN/A for non-human GPCRs
Length357
Amino acid sequenceMDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLLVLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFGWGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVSPVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
UniProtP30966
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3597
IUPHAR10
DrugBankN/A

Known ligands

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Total entries: 60
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
117152D structurepropranololC16H21NO2259.3493 / 23.0Yes
124592D structureCHEMBL338696C22H25FN2O352.4533 / 13.6Yes
136672D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
141052D structureCHEMBL126724C20H21FN2O324.3993 / 14.1Yes
204042D structureCHEMBL338095C21H22ClFN2O372.8683 / 04.7Yes
218552D structureCHEMBL126737C21H22ClFN2O372.8683 / 04.7Yes
265772D structureYohimbineC21H26N2O3354.454 / 22.9Yes
308322D structureCHEMBL129230C22H23FN2O350.4373 / 03.7Yes
390532D structureCHEMBL126823C21H24N2O320.4362 / 03.9Yes
409662D structure16502-01-5C11H12N2172.2311 / 21.5Yes
622182D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
838742D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
1125552D structureCHEMBL338081C22H26N2O334.4632 / 03.6Yes
1170992D structureCHEMBL128184C22H25FN2O2368.4524 / 04.0Yes
1319352D structureCHEMBL129472C22H26N2318.4641 / 04.6Yes
1345282D structureCHEMBL126188C25H26N2O370.4962 / 05.2No
1438422D structureCHEMBL126438C20H22N2O306.4092 / 14.0Yes
1460352D structureCHEMBL96504C21H23FN2O338.4263 / 04.0Yes
1508322D structureCHEMBL338091C21H21FN2O336.413 / 13.7Yes
5540832D structureritanserinC27H25F2N3OS477.5746 / 05.2No
1639592D structurepindololC14H20N2O2248.3263 / 31.8Yes
1676632D structureCHEMBL424258C20H22N2O306.4092 / 14.0Yes
1711722D structure15532-75-9C11H13F3N2230.2345 / 12.3Yes
1748652D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
1756602D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
1766902D structureRU 24969C14H16N2O228.2952 / 21.8Yes
1846712D structureCHEMBL340511C25H26N2O370.4962 / 05.2No
1951972D structureCHEMBL92879C12H14N2186.2581 / 11.4Yes
2083022D structureCHEMBL97518C22H29N3O2367.4933 / 32.9Yes
2390742D structureCHEMBL125361C24H30N2346.5181 / 05.7No
2506722D structureCHEMBL125417C23H28N2332.4911 / 05.1No
2700752D structureCHEMBL129476C22H24N2O332.4472 / 03.6Yes
2715212D structureCHEMBL126574C21H24N2304.4371 / 04.2Yes
2902922D structureserotoninC10H12N2O176.2192 / 30.2Yes
5663722D structureclozapineC18H19ClN4326.8283 / 13.1Yes
2945052D structureCHEMBL126021C15H20N2O244.3382 / 11.6Yes
2990412D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3130122D structuredl-ArterenolC8H11NO3169.184 / 4-1.2Yes
3161502D structureCHEMBL129163C21H22N2O318.422 / 13.6Yes
3198872D structureCHEMBL128099C22H26N2O334.4632 / 04.2Yes
3232922D structureCHEMBL129774C23H24N2328.4591 / 04.4Yes
3269262D structureCHEMBL128945C23H28N2O348.492 / 04.5Yes
3312352D structureCHEMBL2111848C23H26N2330.4751 / 04.6Yes
3312362D structureCHEMBL446356C23H26N2330.4751 / 04.6Yes
3370942D structureCHEMBL128848C21H24N2O320.4362 / 03.9Yes
3418402D structure1011-17-2C10H14N2O178.2353 / 21.0Yes
3551242D structure1-(3-Chlorophenyl)piperazineC10H13ClN2196.6782 / 11.7Yes
3574112D structure2-Bromolysergic acid diethylamideC20H24BrN3O402.3362 / 14.0Yes
3594912D structure1-(1-Naphthyl)piperazineC14H16N2212.2962 / 12.6Yes
3641062D structureBufotenineC12H16N2O204.2732 / 21.2Yes
3671722D structuredopamineC8H11NO2153.1813 / 3-1.0Yes
3759522D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3858002D structure2-Methyl-5-hydroxytryptamineC11H14N2O190.2462 / 31.4Yes
3867482D structureCHEMBL341506C22H25FN2336.4542 / 04.7Yes
3882772D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No
3993752D structurequipazineC13H15N3213.2843 / 11.5Yes
4156022D structureCHEMBL130586C27H28N2O396.5342 / 05.5No
5553912D structureD-Lysergic acidC16H16N2O2268.3163 / 20.0Yes
4236082D structureD-Lysergic acidC16H16N2O2268.3163 / 20.0Yes
4296772D structureCHEMBL128185C22H25FN2O2368.4524 / 04.0Yes

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