Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE WDL-RF ATPbind DockRMSD DeepMSA FASPR

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

GPCR

NameSomatostatin receptor type 4
SpeciesHomo sapiens (Human)
GeneSSTR4
SynonymSS4R
SS4-R
SS-4-R
SRIF2B
SST4 receptor
DiseaseN/A
Length388
Amino acid sequenceMSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
UniProtP31391
Protein Data BankN/A
GPCR-HGmod modelP31391
3D structure modelThis predicted structure model is from GPCR-EXP P31391.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1853
IUPHAR358
DrugBankBE0009273

Known ligands

You can:

Total entries: 990
Page:  / 10 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
6422D structureCHEMBL2112935C23H21N5367.4563 / 23.9Yes
8042D structureCHEMBL406000C60H74N12O101123.3311 / 123.1No
12862D structureBIM 23197C57H81N13O13S31252.5319 / 140.0No
38362D structureCHEMBL1079007C22H27N3O2S397.5376 / 26.0No
46772D structureCHEMBL29102C33H43NO6549.7087 / 14.2No
4419262D structureCHEMBL3350903C55H68N12O12S21153.3416 / 15-0.2No
4419312D structureCHEMBL3350904C55H68N12O12S21153.3416 / 15-0.2No
64212D structureCHEMBL412183C55H68N12O12S21153.3416 / 15-0.2No
64262D structureCHEMBL438546C55H68N12O12S21153.3416 / 15-0.2No
75702D structureCHEMBL451932C55H74ClN13O10S21176.8514 / 143.1No
92122D structureCHEMBL1161333C54H65N11O12S21124.315 / 130.3No
92182D structureCHEMBL2093027C54H65N11O12S21124.315 / 130.3No
94592D structureCHEMBL216992C60H78N12O11S21207.4816 / 140.6No
104792D structureCHEMBL2369756C58H69ClN12O9S21177.8314 / 113.8No
104862D structureCHEMBL1794041C58H69ClN12O9S21177.8314 / 113.8No
105392D structureCHEMBL503379C41H48F3N7O7S839.93212 / 5N/ANo
109302D structureCHEMBL92545C31H34N4O2S526.6994 / 24.4No
109352D structureCHEMBL93618C31H34N4O2S526.6994 / 24.4No
115902D structureCHEMBL410047C62H79N13O14S21294.5118 / 16-1.0No
119012D structureCHEMBL391951C23H29N3O3395.5036 / 15.0Yes
120012D structureCHEMBL502077C78H101ClN18O18S21678.3425 / 18-5.4No
123272D structureCHEMBL265839C76H104N16O18S21593.8823 / 21-0.9No
133702D structureCHEMBL2011461C46H60N8O7837.0358 / 64.3No
135452D structureCHEMBL1077722C21H26N4O3382.4647 / 13.4Yes
4422272D structureCHEMBL3350882C58H72N12O13S21209.4116 / 150.2No
149402D structureCHEMBL263292C58H72N12O13S21209.4116 / 150.2No
149602D structureCHEMBL504838C35H38F3N5O5665.7149 / 5N/ANo
149682D structureCHEMBL462020C35H38F3N5O5665.7149 / 5N/ANo
152122D structureCHEMBL429164C84H111N17O18S21711.0323 / 210.0No
159502D structureCHEMBL254500C26H30BrN5O2524.4634 / 13.1No
159622D structureCHEMBL252231C26H30BrN5O2524.4634 / 13.1No
5219262D structureAM-0902C17H15ClN6O2370.7976 / 02.3Yes
162932D structureBDBM84629C71H81N11O91232.511 / 128.1No
171192D structureCHEMBL406260C58H70N12O8S21127.3913 / 114.0No
4423332D structureCHEMBL3349676C58H70N12O8S21127.3913 / 114.0No
175842D structureCHEMBL447177C58H72ClN15O13S21286.8817 / 17-1.7No
180932D structureCHEMBL413888C81H106N16O17S21639.9522 / 200.7No
4423812D structureCHEMBL3349610C52H71N11O10S21074.3314 / 131.9No
185452D structureCHEMBL2370299C52H71N11O10S21074.3314 / 131.9No
189522D structureCHEMBL3122128C81H111N17O23S21754.9930 / 19-9.1No
199152D structureCHEMBL1223226C51H68N10O10981.16512 / 131.7No
206352D structureCHEMBL414544C57H69N9O11S21120.3515 / 122.2No
206412D structureCHEMBL2371100C57H69N9O11S21120.3515 / 122.2No
206472D structureCHEMBL2371108C57H69N9O11S21120.3515 / 122.2No
4424842D structureCHEMBL3350357C57H69N9O11S21120.3515 / 122.2No
206492D structureCHEMBL414272C57H69N9O11S21120.3515 / 122.2No
206562D structureCHEMBL428281C57H69N9O11S21120.3515 / 122.2No
206592D structureCHEMBL2111200C57H69N9O11S21120.3515 / 122.2No
206642D structureCHEMBL2111257C57H69N9O11S21120.3515 / 122.2No
206682D structureCHEMBL264046C57H69N9O11S21120.3515 / 122.2No
206732D structureCHEMBL415582C57H69N9O11S21120.3515 / 122.2No
246832D structureCHEMBL387005C73H99IN16O15S21631.7220 / 181.9No
250782D structureCHEMBL384836C50H67N11O11S21062.2715 / 130.4No
255902D structureCHEMBL440074C81H105IN16O17S21765.8522 / 201.4No
261652D structureCHEMBL176730C30H31N5461.6132 / 36.2No
262632D structureCHEMBL1078449C23H30N4O3410.5187 / 24.2Yes
267482D structureCHEMBL434159C27H28N6OS484.6226 / 23.7Yes
4427332D structureCHEMBL3349599C56H62N8O8975.169 / 85.5No
276002D structureCHEMBL409754C58H70N12O9S21143.3914 / 123.6No
4427412D structureCHEMBL3349669C58H70N12O9S21143.3914 / 123.6No
280772D structuresst4-selective analogue 17C53H62N11O12S2-1109.2615 / 131.2No
286302D structureBDBM50136762C55H67N12O11S2-1136.3315 / 113.7No
288032D structureCHEMBL2369735C56H68ClN13O9S21166.8114 / 122.6No
288102D structureCHEMBL1793861C56H68ClN13O9S21166.8114 / 122.6No
290092D structureCHEMBL282129C42H51N3O5677.8867 / 36.0No
4428562D structureCHEMBL3349508C66H78ClN11O101220.8712 / 136.6No
305432D structureCHEMBL1793962C66H78ClN11O101220.8712 / 136.6No
4428592D structureCHEMBL3349506C66H78ClN11O101220.8712 / 136.6No
305472D structureCHEMBL1793960C66H78ClN11O101220.8712 / 136.6No
309192D structureCHEMBL3122125C82H126N22O27S21916.1635 / 26-14.6No
330092D structureCHEMBL1791305C74H102N20O19S21639.8726 / 22-5.2No
338662D structureCHEMBL437448C54H66Br2N12O8S21235.1313 / 114.1No
362712D structureCHEMBL502219C59H70ClN13O10S21220.8614 / 143.2No
362912D structureCHEMBL442605C28H35N5O3489.624 / 42.3Yes
373902D structureCHEMBL1794043C60H71N13O9S21182.4314 / 123.3No
373922D structureCHEMBL2369758C60H71N13O9S21182.4314 / 123.3No
375692D structureCHEMBL408471C56H67N11O9S21102.3412 / 113.9No
376532D structureCHEMBL414446C57H68IN9O10S21230.2514 / 113.2No
376612D structureCHEMBL407649C57H68IN9O10S21230.2514 / 113.2No
385732D structureCHEMBL538948C61H72IN11O10S21310.3414 / 134.5No
385782D structureCHEMBL538948C61H72IN11O10S21308.3414 / 134.5No
392952D structureL-362855C57H70N10O81023.259 / 115.7No
5227272D structureCHEMBL3780496C24H24ClNO2393.9113 / 15.3No
404032D structureCHEMBL559022C74H96IN15O15S21626.720 / 193.5No
404102D structureCHEMBL559022C74H96IN15O15S21624.720 / 193.5No
404432D structureCHEMBL267054C51H70N10O10983.18112 / 131.7No
408302D structureCHEMBL291474C41H49N3O6679.8588 / 25.2No
408962D structureCHEMBL3218121C36H50N6O5646.8336 / 30.8No
413302D structureCHEMBL436962C61H78N12O14S21267.4818 / 160.1No
413842D structureCHEMBL439077C63H76N12O12S21257.4917 / 151.4No
413912D structureCHEMBL437085C63H76N12O12S21257.4917 / 151.4No
4433202D structureCHEMBL3350894C63H76N12O12S21257.4917 / 151.4No
4433272D structureCHEMBL3350893C63H76N12O12S21257.4917 / 151.4No
419892D structureCHEMBL508585C70H92N16O20S21541.7227 / 17-6.0No
430962D structureCHEMBL2112223C30H37N5O2499.6593 / 43.9Yes
432682D structureCHEMBL262551C83H111N15O16S21639.0122 / 182.4No
436232D structureCHEMBL466609C34H39N5O3565.7184 / 43.8No
436282D structureCHEMBL476240C34H39N5O3565.7184 / 43.8No
442592D structureCHEMBL444639C77H99N13O15S21510.8320 / 162.9No
451252D structureCHEMBL414717C74H97N15O15S21500.820 / 192.8No

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218