Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

GPCR

NameGastrin/cholecystokinin type B receptor
SpeciesHomo sapiens (Human)
GeneCCKBR
SynonymCCK-B receptor
CCK-B receptor {ECO:0000303|PubMed:8415658}
CCK-B/gastrin receptor
CCK-BR
gastrin/cholecystokinin type B receptor
[ Show all ]
DiseaseDiagnostic imaging
Duodenal ulcers
Gastroesophageal reflux disease
Gastrointestinal disease
Intestine cancer
[ Show all ]
Length447
Amino acid sequenceMELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
UniProtP32239
Protein Data BankN/A
GPCR-HGmod modelP32239
3D structure modelThis predicted structure model is from GPCR-EXP P32239.
BioLiPN/A
Therapeutic Target DatabaseT05849
ChEMBLCHEMBL298
IUPHAR77
DrugBankBE0001158

Known ligands

You can:

Total entries: 1760
Page:  / 18 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
742D structureCHEMBL504861C34H31FN4O4578.6447 / 16.3No
1192D structureCHEMBL343158C21H18FN3OS379.4535 / 23.8Yes
6292D structureCHEMBL37699C25H20BrN3O2474.3583 / 15.1No
10392D structureCHEMBL217353C19H19BrN4O3S2495.417 / 03.5Yes
10922D structureCHEMBL140749C22H22FN3OS395.4965 / 23.7Yes
13202D structureCHEMBL389713C31H36N6O5572.6667 / 24.6No
18482D structureCHEMBL336690C22H26FN3O2383.4675 / 14.4Yes
18702D structureCHEMBL261682C20H19BrN4O3S475.3616 / 13.3Yes
19952D structureCHEMBL293026C44H52N8O10852.94610 / 103.7No
22152D structureCHEMBL411271C53H71N9O15S1106.2615 / 104.5No
32162D structureCHEMBL354049C33H40N4O5572.7066 / 54.8No
32192D structureCHEMBL83942C33H40N4O5576.7226 / 54.8No
40252D structureCHEMBL2110202C25H29N9O2487.5687 / 43.2Yes
42272D structureCHEMBL570521C21H15Cl3N4O3S2541.8467 / 26.0No
47242D structureCHEMBL292856C28H36N8O3532.6496 / 43.5No
50162D structureCHEMBL432266C33H32FN9O3621.6778 / 33.8No
55622D structureCHEMBL140495C24H22FN3O2403.4575 / 24.4Yes
56502D structureCCK-A Agonist 34C35H32FN5O4605.676 / 15.7No
57982D structureCHEMBL283914C35H38Cl2N4O6681.6116 / 45.9No
58392D structureBDBM50321606C80H98N18O141535.7817 / 182.2No
59922D structureCCK-A Agonist 20C37H36N4O4600.7194 / 16.4No
60992D structureCHEMBL566177C25H18BrCl2FN4O5S656.3049 / 25.5No
64482D structureCHEMBL404967C30H34N6O6574.6387 / 24.1No
64502D structureCHEMBL565298C22H15BrClFN4O5S2613.85710 / 35.1No
65472D structureCHEMBL424076C25H20N4O2408.4613 / 23.7Yes
70572D structureCHEMBL357983C30H34N4O6546.6246 / 33.8No
72722D structureCHEMBL3144540C45H57N7O10855.9910 / 83.8No
72732D structureCHEMBL60731C45H57N7O10855.9910 / 83.8No
75492D structureCHEMBL97133C34H42N4O3554.7353 / 35.7No
75862D structureCHEMBL3144554C45H55N7O10853.97410 / 84.0No
4420132D structureCHEMBL3351053C39H49N5O7699.8498 / 52.8No
4420142D structureCHEMBL3351062C39H49N5O7699.8498 / 52.8No
76752D structureCHEMBL294954C39H49N5O7699.8498 / 52.8No
76772D structureCHEMBL49259C39H49N5O7699.8498 / 52.8No
77232D structureCHEMBL319196C28H33N3O4475.5894 / 24.2Yes
84812D structureCHEMBL339515C29H30Cl2N4O3553.4843 / 35.5No
85252D structureCHEMBL217715C19H19ClN4O4S2466.9558 / 13.8Yes
85502D structureCHEMBL127397C30H34N4O3498.6273 / 34.6Yes
87342D structureCHEMBL443550C25H21Cl2N3O2466.3623 / 15.2No
89442D structureCHEMBL137208C25H24N4O2412.4933 / 23.8Yes
93262D structureCHEMBL336749C23H19FN4O2402.4294 / 23.0Yes
98672D structureAC-42C20H31NO301.4742 / 05.2No
100092D structureCHEMBL102867C27H26Cl2N4O3525.433 / 25.2No
106212D structureCholecystokinin-9C55H74N14O17S31299.4621 / 16-4.1No
106822D structureCHEMBL413654C97H126N20O32S2116.2434 / 27-3.9No
114912D structureCHEMBL3144564C44H53N7O13S920.00413 / 93.1No
115082D structureCHEMBL135988C21H24N4O2364.4493 / 22.4Yes
116472D structureCHEMBL2111654C31H34N4O5542.6365 / 23.5No
127122D structureCHEMBL1907850C23H17BrFN3O2466.314 / 13.6Yes
129112D structureCHEMBL293490C33H39N5O6S633.7646 / 43.8No
131762D structureCHEMBL399918C18H19BrN2O5S2487.3837 / 13.9Yes
132542D structureCHEMBL101803C26H33N3O3435.5683 / 24.5Yes
135952D structureCHEMBL355319C27H29N3O4459.5464 / 24.6Yes
138842D structureCHEMBL380907C32H41N5O3543.7125 / 15.9No
140052D structureCHEMBL3144543C44H55N7O11857.96211 / 103.2No
140082D structureCHEMBL62184C44H55N7O11857.96211 / 103.2No
143792D structureCHEMBL342614C24H19ClN4O4462.895 / 33.7Yes
144532D structureCHEMBL70883C28H23FN4O4498.5146 / 24.5Yes
149272D structureCHEMBL287564C34H48Cl2N4O6679.686 / 45.9No
149282D structureCHEMBL34101C34H48Cl2N4O6679.686 / 45.9No
152682D structureCHEMBL332595C28H30N4O3470.5733 / 25.1No
160852D structureCHEMBL502398C56H67N9O121058.214 / 83.2No
163812D structureCHEMBL22630C21H16FN3O4393.3746 / 22.5Yes
171062D structureCHEMBL264273C61H83N11O17S1274.4517 / 134.1No
171092D structureCHEMBL1907839C23H18IN3O2495.323 / 14.4Yes
172432D structureCHEMBL1907842C24H18F3N3O2437.4226 / 14.1Yes
172462D structureCHEMBL2092865C24H18F3N3O2437.4226 / 14.1Yes
182162D structureCHEMBL285739C33H40Cl2N4O6659.6056 / 34.7No
183762D structureCHEMBL105527C30H33N3O3483.6123 / 25.0Yes
186182D structureCHEMBL390276C32H32N4O5552.6316 / 25.4No
187802D structureCHEMBL118610C35H46N6O7662.7887 / 63.2No
192532D structureCHEMBL321800C31H35N3O4513.6384 / 24.5No
198692D structureCHEMBL32301C25H30N4O4450.5394 / 43.0Yes
200072D structureCHEMBL306958C23H19FN4O2402.4294 / 23.5Yes
202142D structureCHEMBL53234C23H17ClN6O428.884 / 23.7Yes
209132D structureCHEMBL328422C44H56N8O9840.9799 / 94.1No
209162D structureCHEMBL319311C44H56N8O9840.9799 / 94.1No
210122D structureCHEMBL177799C35H44N6O7660.7727 / 72.8No
210172D structureCHEMBL2371222C35H44N6O7660.7727 / 72.8No
210192D structureCHEMBL2371223C35H44N6O7660.7727 / 72.8No
212812D structureCHEMBL277661C22H18N2O4374.3964 / 23.4Yes
212832D structureCHEMBL22918C22H18N2O4374.3964 / 23.4Yes
213702D structureCHEMBL350853C23H27N5O2405.5023 / 22.7Yes
218382D structure131449-37-1C45H55N7O10853.97410 / 83.9No
218422D structureCHEMBL433640C45H55N7O10853.97410 / 83.9No
219972D structureCHEMBL3143025C42H51N9O11857.92211 / 93.2No
219982D structureCHEMBL7423C42H51N9O11857.92211 / 93.2No
220122D structureCHEMBL34335C24H29N3O4423.5134 / 23.7Yes
5221212D structureCHEMBL3775436C15H26ClNO3303.8274 / 3N/AN/A
5221892D structureCHEMBL3775769C15H26ClNO3303.8274 / 3N/AN/A
222122D structureCHEMBL410905C20H20BrN3O3S2494.4226 / 14.9Yes
225992D structureCHEMBL301261C31H34N4O5542.6365 / 44.1No
226162D structureCHEMBL420459C32H42N4O3530.7133 / 27.4No
226432D structureCHEMBL74170C27H27N3O2425.5323 / 25.9No
236902D structureCHEMBL303386C30H32N4O4512.615 / 24.8No
238292D structureCHEMBL115656C31H38N4O2498.6713 / 26.7No
238312D structureCHEMBL115456C31H38N4O2498.6713 / 26.7No
4426102D structureTalnetantC25H22N2O2382.4633 / 25.7No
243972D structureCHEMBL30592C30H35Cl2N3O5588.5265 / 35.8No
243982D structureCHEMBL30481C30H35Cl2N3O5588.5265 / 35.8No

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218