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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 7
SpeciesMus musculus (Mouse)
GeneHtr7
SynonymGPRFO
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
5-HTx
5-HT7 receptor
5-HT7
[ Show all ]
DiseaseN/A for non-human GPCRs
Length448
Amino acid sequenceMMDVNSSGRPDLYGHLRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFPEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNCDHCGKKGHDT
UniProtP32304
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4764
IUPHAR12
DrugBankN/A

Known ligands

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Total entries: 40
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
136632D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
167772D structurePipamperoneC21H30FN3O2375.4885 / 12.0Yes
5367482D structureLP-211C30H34N4O466.6294 / 15.0Yes
5535172D structurecisaprideC23H29ClFN3O4465.957 / 23.4Yes
621972D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
5377632D structureCHEMBL3925231C21H27N3O2353.4665 / 02.8Yes
5595422D structureSCHEMBL14061868C21H27N3O2353.4665 / 02.8Yes
5536872D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
1091482D structureSERTINDOLEC24H26ClFN4O440.9473 / 14.1Yes
1121852D structurezotepineC18H18ClNOS331.8583 / 04.8Yes
1540332D structureMesulergineC18H26N4O2S362.4925 / 11.4Yes
1593502D structure5-METHOXYTRYPTAMINEC11H14N2O190.2462 / 20.5Yes
5541412D structure15532-75-9C11H13F3N2230.2345 / 12.3Yes
1748952D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
5541722D structureamitriptylineC20H23N277.4111 / 05.0Yes
5541752D structureRU 24969C14H16N2O228.2952 / 21.8Yes
1915462D structurehaloperidolC21H23ClFNO2375.8684 / 13.2Yes
2155372D structureZiprasidoneC21H21ClN4OS412.9365 / 14.0Yes
5186952D structurebromocriptineC32H40BrN5O5654.6066 / 33.8No
5545472D structureDihydroergokryptineC32H43N5O5577.7266 / 33.1No
2637322D structurePaliperidoneC23H27FN4O3426.4927 / 12.2Yes
5512852D structureCHEMBL3897426C31H35FN4O2514.6456 / 15.1No
5547062D structurebuspironeC21H31N5O2385.5126 / 02.6Yes
2903182D structureserotoninC10H12N2O176.2192 / 30.2Yes
5663642D structureclozapineC18H19ClN4326.8283 / 13.1Yes
2914982D structurerisperidoneC23H27FN4O2410.4936 / 02.7Yes
2970502D structureFluspiperoneC23H25F2N3O2413.4696 / 13.1Yes
2990402D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3349842D structure(S)-mianserinC18H20N2264.3722 / 03.4Yes
5549472D structuremianserinC18H20N2264.3722 / 03.4Yes
3436752D structurequetiapineC21H25N3O2S383.515 / 12.1Yes
3574192D structure2-Bromolysergic acid diethylamideC20H24BrN3O402.3362 / 14.0Yes
3634172D structureAsenapineC17H16ClNO285.7712 / 03.8Yes
5550942D structureBufotenineC12H16N2O204.2732 / 21.2Yes
3759732D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3861402D structuremetergolineC25H29N3O2403.5263 / 13.8Yes
3882842D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No
5475862D structureCHEMBL3946661C21H26N2O2338.4514 / 03.5Yes
4340372D structurechlorpromazineC17H19ClN2S318.8633 / 05.2No
4412202D structure(+)-ButaclamolC25H31NO361.5292 / 15.0Yes

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