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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 2C
SpeciesMus musculus (Mouse)
GeneHtr2c
Synonym5-HT-1C
serotonin 1c receptor
HTR1C
5-hydroxytryptamine receptor 1C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
[ Show all ]
DiseaseN/A for non-human GPCRs
Length459
Amino acid sequenceMVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELRNISLNFLKCCCKKGDEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV
UniProtP34968
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3006
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 17
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
201752D structureimipramineC19H24N2280.4152 / 04.8Yes
231762D structure1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amineC11H16INO2321.1583 / 12.5Yes
266052D structureYohimbineC21H26N2O3354.454 / 22.9Yes
943662D structureCHEMBL47482C15H15N209.2921 / 12.7Yes
1282002D structureRS-102221C27H31F3N4O7S612.62112 / 32.7No
1522222D structureCYPROHEPTADINEC21H21N287.4061 / 04.7Yes
1997612D structure159277-08-4C11H14F3NO2249.2336 / 12.1Yes
2432892D structure143797-63-1C15H14N4O266.3042 / 21.5Yes
5433322D structureCHEMBL3946540C21H25ClN2O2372.8934 / 04.1Yes
2799392D structureSB 206553C17H16N4O292.3422 / 11.7Yes
5441172D structureCHEMBL3986651C22H28N2O3368.4775 / 03.4Yes
5442292D structureCHEMBL3942898C21H25FN2O2356.4415 / 03.6Yes
3442922D structureSB 204741C14H14N4OS286.3533 / 22.4Yes
3790012D structureRacemic DOTFMC12H16F3NO2263.266 / 12.8Yes
5531122D structureCHEMBL3963147C22H27N3O3381.4765 / 02.8Yes
5706002D structureSCHEMBL15746102C22H27N3O3381.4765 / 02.8Yes
5475852D structureCHEMBL3946661C21H26N2O2338.4514 / 03.5Yes

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