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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameCannabinoid receptor 2
SpeciesHomo sapiens (Human)
GeneCNR2
SynonymPeripheral cannabinoid receptor
rCB2
hCB2
cannabinoid receptor 2 (macrophage)
cannabinoid receptor 2 (spleen)
[ Show all ]
DiseaseImmune disorder
Inflammatory bowel disease
Inflammatory disease
Neuropathic pain
Osteoporosis
[ Show all ]
Length360
Amino acid sequenceMEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
UniProtP34972
Protein Data Bank5zty
GPCR-HGmod modelP34972
3D structure modelThis structure is from PDB ID 5zty.
BioLiPBL0438927
Therapeutic Target DatabaseT37693
ChEMBLCHEMBL253
IUPHAR57
DrugBankBE0000095

Known ligands

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Total entries: 8120
Page:  / 82 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
162D structureCHEMBL2063242C23H23Cl2N3O3460.3554 / 14.7Yes
262D structureN-(4-methoxybenzyl)oleamideC26H43NO2401.6352 / 18.5No
2352D structureCHEMBL204391C23H16Cl3N3O2472.753 / 14.8Yes
2782D structureCHEMBL2205617C21H20F4N2O3S456.4568 / 14.3Yes
4416832D structureCHEMBL3322349C25H29Cl3N4O507.8843 / 27.0No
4562D structureCHEMBL572080C30H29ClN4O2513.0385 / 26.2No
4652D structureCHEMBL294472C25H36O3384.563 / 17.0No
4662D structureCHEMBL59540C25H36O3384.563 / 17.0No
5052D structureCHEMBL481508C18H27N3O2S2381.5536 / 05.8No
5582D structureCHEMBL558564C20H20Cl5N5O523.6644 / 3N/ANo
5339152D structureCHEMBL3937055C16H19F2N3O5S403.4018 / 20.6Yes
5882D structureCHEMBL1223776C25H35N3O393.5753 / 15.4No
6062D structureCHEMBL2153673C28H27Cl2N5O3S584.5165 / 25.6No
5197012D structureCHEMBL3924062C21H28N4O3384.486 / 14.2Yes
6662D structureCHEMBL392836C21H15Cl3N2O417.7143 / 06.8No
7232D structureCHEMBL411504C24H31N3O4S457.5896 / 04.1Yes
5197032D structureCHEMBL3915356C29H20Cl2F3N3O554.3946 / 27.0No
8352D structureCHEMBL88548C18H15Cl3N4O409.6953 / 25.2No
8582D structureCHEMBL1641939C26H32N2O2404.5543 / 15.7No
5359362D structureCHEMBL3936958C20H22F3N3O3S441.4698 / 13.8Yes
5359382D structureCHEMBL3903525C19H24F2N4O4410.4229 / 12.8Yes
10662D structureCHEMBL2205606C20H20F2N2O5S438.4468 / 13.1Yes
4592432D structureCHEMBL1076680C19H16Cl2O3S395.2944 / 15.3No
11712D structureCHEMBL2064052C22H24O4352.434 / 23.8Yes
11812D structureCHEMBL3290443C21H18Cl2N4O3445.35 / 14.8Yes
13122D structureCHEMBL1080908C23H25ClF3N5O2S527.9918 / 14.8No
13152D structureCHEMBL1080545C23H25ClF3N5O2S527.9918 / 14.8No
13162D structureCHEMBL1081213C23H25ClF3N5O2S527.9918 / 14.8No
14272D structureCHEMBL570193C18H20Cl2N2335.2722 / 05.9No
5197072D structureCHEMBL3908425C21H27F2N5O3435.4769 / 03.0Yes
15522D structure875014-22-5C25H32N2OS408.6042 / 17.4No
16042D structureCHEMBL488787C29H20Cl3N7O588.8776 / 06.9No
16722D structureCHEMBL584528C20H21F4NO2383.3876 / 04.0Yes
16822D structureCHEMBL2179751C29H35N3O2457.6183 / 25.6No
5359632D structureCHEMBL3900220C18H23N5O3357.4145 / 20.3Yes
20062D structureCHEMBL2152810C28H32N2O2S460.6364 / 16.6No
20242D structureCHEMBL271839C23H31NO2353.5062 / 04.7Yes
5359702D structureCHEMBL3925964C29H27ClF3N3O5S622.05610 / 35.0No
20422D structureCHEMBL478643C23H22BrNO408.3391 / 15.8No
5359762D structureCHEMBL225622C25H24Cl3N3O488.8372 / 17.7No
20922D structureCHEMBL2163952C30H32N2O3468.5974 / 15.9No
5479212D structureCHEMBL3911884C15H21ClN2O3312.7944 / 22.3Yes
5573632D structureSCHEMBL15790159C15H21ClN2O3312.7944 / 22.3Yes
5359772D structureCHEMBL3911641C15H21ClN2O3312.7944 / 22.3Yes
23492D structureCHEMBL1762420C18H28N4O4364.4465 / 11.2Yes
4417672D structureCHEMBL3401612C21H21Cl2N3O402.3192 / 15.5No
23642D structureCHEMBL475910C29H26BrNO484.4371 / 17.3No
23822D structureCHEMBL1801072C25H24FN5O4477.4967 / 23.7Yes
5359832D structureSCHEMBL17557589C28H28Cl2N4O3S571.5177 / 25.6No
30072D structureCHEMBL464916C21H27N3O337.4673 / 24.8Yes
30102D structureCHEMBL3114514C21H16FN3O345.3773 / 24.3Yes
4632402D structureCHEMBL3605035C20H14Cl2O3373.2293 / 25.8No
30662D structureCHEMBL511558C25H14Cl3N3O478.7573 / 16.8No
5359862D structureBDBM118149C36H31Cl2N3O3624.5624 / 17.9No
30722D structureCHEMBL2163572C29H38N4O3490.6486 / 14.2Yes
30892D structureCHEMBL2336550C23H26N2O2S394.5334 / 04.5Yes
4592522D structureCHEMBL3669096C23H22FN5O2419.468 / 15.0Yes
33362D structureCID 11668762C21H14Cl2N2OS413.3162 / 06.0No
5360012D structureSCHEMBL16023414C17H18F2N6O360.3698 / 02.2Yes
34752D structureAC1LEVMSC17H13NO2263.2963 / 03.7Yes
5360032D structureSCHEMBL17557608C34H30Cl2N4O5S677.5979 / 27.5No
35182D structureCHEMBL263632C19H30O2290.4472 / 23.8Yes
35432D structureCHEMBL1765270C24H28N2O2376.53 / 13.4Yes
35632D structureCHEMBL515648C22H18ClFN4O408.8616 / 05.3No
35662D structureCHEMBL478202C22H18ClFN4O408.8616 / 05.3No
35862D structureCHEMBL2380424C25H25NO2371.482 / 05.7No
5360062D structureSCHEMBL16222656C20H23ClN6O2S446.9547 / 02.4Yes
5360112D structureSCHEMBL17557600C35H32Cl2N4O2611.5676 / 26.3No
37362D structureCHEMBL449341C17H14Cl2N2O3S397.274 / 14.2Yes
39232D structureCHEMBL2179729C21H26N2O2338.4512 / 24.0Yes
39702D structureCHEMBL1091832C25H20Cl2N2O4483.3455 / 26.3No
40032D structureCHEMBL518505C23H22BrCl2N3O507.2532 / 17.1No
40662D structureAC1LP5MHC19H16N2O2S336.4094 / 04.1Yes
5360332D structureSCHEMBL16211797C18H21ClN6S388.9186 / 03.9Yes
41462D structureCHEMBL2347042C21H21Cl3N2407.7631 / 08.3No
4418792D structureCHEMBL3401608C20H19ClN2O3370.8333 / 24.9Yes
41872D structureCID 56595575C24H28N4O2404.5144 / 02.7Yes
41942D structureCHEMBL2316259C25H34N2O2S426.6194 / 16.4No
42612D structureCHEMBL2381791C29H36N4O2472.6334 / 16.4No
43652D structureCHEMBL576709C15H14F2N2O276.2875 / 02.8Yes
44232D structureCHEMBL2071068C24H28ClN3O2425.9573 / 34.7Yes
5360452D structureSCHEMBL18548029C27H23Cl2F3N4O3S611.4619 / 06.8No
44562D structureCHEMBL2172461C11H20N2O4244.2915 / 20.4Yes
45542D structureUNII-4MC625LVIDC21H29NO2327.4682 / 14.1Yes
4418912D structureCHEMBL3353830C21H19N5S373.4785 / 04.3Yes
5479502D structureCHEMBL3930886C29H24Cl2N4O515.4383 / 16.3No
5574152D structureSCHEMBL15776122C18H22FN3O3347.395 / 12.1Yes
5479522D structureCHEMBL3891188C18H22FN3O3347.395 / 12.1Yes
5360582D structureCHEMBL3898811C18H22FN3O3347.395 / 12.1Yes
5360612D structureSCHEMBL18548061C37H36Cl2N4O4S703.6796 / 17.3No
48612D structureCHEMBL397690C18H19ClN2O2S362.8724 / 13.8Yes
5360642D structureSCHEMBL18547958C35H33Cl2N3O3S646.6275 / 08.0No
49912D structureCHEMBL2023578C27H34N2O4450.5794 / 25.7No
50722D structureSCHEMBL2485239C24H32Cl2N6O491.4616 / 1N/AN/A
50732D structurePhAR, CycloproylC26H43NO4433.6334 / 27.0No
51072D structureCHEMBL256781C24H30N2O4S442.5745 / 03.9Yes
51182D structureCHEMBL225414C21H18Br2N2O2490.1952 / 34.6Yes
52592D structureCHEMBL157591C24H20ClF3N4O2S520.9557 / 15.5No
5574252D structureSCHEMBL17557708C33H28Cl2N4O2583.5136 / 25.5No
53312D structureCHEMBL600426C23H35NO341.5392 / 07.4No

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