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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameSomatostatin receptor type 5
SpeciesHomo sapiens (Human)
GeneSSTR5
SynonymSOMATO
SS-5-R
SS5-R
SS5R
SST5 receptor
DiseaseN/A
Length364
Amino acid sequenceMEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
UniProtP35346
Protein Data BankN/A
GPCR-HGmod modelP35346
3D structure modelThis predicted structure model is from GPCR-EXP P35346.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1792
IUPHAR359
DrugBankBE0002147

Known ligands

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Total entries: 1227
Page:  / 13 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
1972D structureCHEMBL363712C27H29N5S455.6244 / 25.3No
6402D structureCHEMBL2112935C23H21N5367.4563 / 23.9Yes
8072D structureCHEMBL406000C60H74N12O101123.3311 / 123.1No
12852D structureBIM 23197C57H81N13O13S31252.5319 / 140.0No
16602D structureCHEMBL3665855C27H26F3N3O5529.51610 / 12.0No
30182D structureCHEMBL236787C28H28FN5453.5654 / 25.7No
38332D structureCHEMBL1079007C22H27N3O2S397.5376 / 26.0No
42812D structureSCHEMBL673266C29H33N3O5S535.6598 / 13.0No
46752D structureCHEMBL29102C33H43NO6549.7087 / 14.2No
4419272D structureCHEMBL3350903C55H68N12O12S21153.3416 / 15-0.2No
4419332D structureCHEMBL3350904C55H68N12O12S21153.3416 / 15-0.2No
64242D structureCHEMBL412183C55H68N12O12S21153.3416 / 15-0.2No
64252D structureCHEMBL438546C55H68N12O12S21153.3416 / 15-0.2No
74312D structureCHEMBL1210209C29H35FN4O3506.6227 / 24.9No
75672D structureCHEMBL451932C55H74ClN13O10S21176.8514 / 143.1No
92142D structureCHEMBL1161333C54H65N11O12S21124.315 / 130.3No
92202D structureCHEMBL2093027C54H65N11O12S21124.315 / 130.3No
94572D structureCHEMBL216992C60H78N12O11S21207.4816 / 140.6No
95862D structureCHEMBL3665814C32H32F4N2O6616.6111 / 13.9No
104812D structureCHEMBL2369756C58H69ClN12O9S21177.8314 / 113.8No
104832D structureCHEMBL1794041C58H69ClN12O9S21177.8314 / 113.8No
105382D structureCHEMBL503379C41H48F3N7O7S839.93212 / 5N/ANo
109272D structureCHEMBL92545C31H34N4O2S526.6994 / 24.4No
109332D structureCHEMBL93618C31H34N4O2S526.6994 / 24.4No
115912D structureCHEMBL410047C62H79N13O14S21294.5118 / 16-1.0No
119022D structureCHEMBL391951C23H29N3O3395.5036 / 15.0Yes
120032D structureCHEMBL502077C78H101ClN18O18S21678.3425 / 18-5.4No
123252D structureCHEMBL265839C76H104N16O18S21593.8823 / 21-0.9No
126462D structureCHEMBL3670744C32H34N4O5554.6477 / 12.5No
128252D structureCHEMBL3665819C32H35FN2O7578.6379 / 13.0No
130802D structureCHEMBL429166C60H73ClN12O8S21189.8913 / 115.4No
133672D structureCHEMBL2011461C46H60N8O7837.0358 / 64.3No
135432D structureCHEMBL1077722C21H26N4O3382.4647 / 13.4Yes
4422262D structureCHEMBL3350882C58H72N12O13S21209.4116 / 150.2No
149392D structureCHEMBL263292C58H72N12O13S21209.4116 / 150.2No
149592D structureCHEMBL504838C35H38F3N5O5665.7149 / 5N/ANo
149672D structureCHEMBL462020C35H38F3N5O5665.7149 / 5N/ANo
152092D structureCHEMBL429164C84H111N17O18S21711.0323 / 210.0No
159542D structureCHEMBL254500C26H30BrN5O2524.4634 / 13.1No
159652D structureCHEMBL252231C26H30BrN5O2524.4634 / 13.1No
162922D structureBDBM84629C71H81N11O91232.511 / 128.1No
171182D structureCHEMBL406260C58H70N12O8S21127.3913 / 114.0No
4423342D structureCHEMBL3349676C58H70N12O8S21127.3913 / 114.0No
175752D structureCHEMBL3665775C29H31F3N4O4556.5869 / 12.4No
175872D structureCHEMBL447177C58H72ClN15O13S21286.8817 / 17-1.7No
180942D structureCHEMBL413888C81H106N16O17S21639.9522 / 200.7No
181092D structureCHEMBL238057C22H27N3O2S397.5376 / 15.1No
182132D structureCHEMBL191171C24H25N5S2447.6195 / 24.8Yes
4423852D structureCHEMBL3349610C52H71N11O10S21074.3314 / 131.9No
185422D structureCHEMBL2370299C52H71N11O10S21074.3314 / 131.9No
189542D structureCHEMBL3122128C81H111N17O23S21754.9930 / 19-9.1No
190082D structureSA VC46H62N8O6823.0528 / 84.6No
5481162D structureCHEMBL3974262C78H100N16O10S1453.8214 / 156.1No
5578792D structureBDBM144786C78H100N16O10S1453.8214 / 156.1No
199142D structureCHEMBL1223226C51H68N10O10981.16512 / 131.7No
202222D structureCHEMBL393515C32H33FN4O2524.646 / 16.7No
206342D structureCHEMBL414544C57H69N9O11S21120.3515 / 122.2No
206402D structureCHEMBL2371100C57H69N9O11S21120.3515 / 122.2No
206432D structureCHEMBL2371108C57H69N9O11S21120.3515 / 122.2No
4424812D structureCHEMBL3350357C57H69N9O11S21120.3515 / 122.2No
206482D structureCHEMBL414272C57H69N9O11S21120.3515 / 122.2No
206532D structureCHEMBL428281C57H69N9O11S21120.3515 / 122.2No
206602D structureCHEMBL2111200C57H69N9O11S21120.3515 / 122.2No
206632D structureCHEMBL2111257C57H69N9O11S21120.3515 / 122.2No
206702D structureCHEMBL264046C57H69N9O11S21120.3515 / 122.2No
206742D structureCHEMBL415582C57H69N9O11S21120.3515 / 122.2No
207352D structureSCHEMBL671295C27H31N3O5477.5616 / 11.4Yes
209282D structureCHEMBL236607C27H28F2N4446.5465 / 16.1No
234322D structureCHEMBL364418C25H25FN6S460.5756 / 24.1Yes
246852D structureCHEMBL387005C73H99IN16O15S21631.7220 / 181.9No
250812D structureCHEMBL384836C50H67N11O11S21062.2715 / 130.4No
255882D structureCHEMBL440074C81H105IN16O17S21765.8522 / 201.4No
261642D structureCHEMBL176730C30H31N5461.6132 / 36.2No
262372D structureCHEMBL3665799C27H27F3N4O4528.5329 / 11.4No
262642D structureCHEMBL1078449C23H30N4O3410.5187 / 24.2Yes
267492D structureCHEMBL434159C27H28N6OS484.6226 / 23.7Yes
4427312D structureCHEMBL3349599C56H62N8O8975.169 / 85.5No
275962D structureCHEMBL409754C58H70N12O9S21143.3914 / 123.6No
4427402D structureCHEMBL3349669C58H70N12O9S21143.3914 / 123.6No
280782D structuresst4-selective analogue 17C53H62N11O12S2-1109.2615 / 131.2No
286112D structureSA IIC38H54N8O6718.98 / 92.6No
286322D structureBDBM50136762C55H67N12O11S2-1136.3315 / 113.7No
287992D structureCHEMBL3665784C25H23F3N4O4500.4789 / 10.9No
288062D structureCHEMBL2369735C56H68ClN13O9S21166.8114 / 122.6No
288112D structureCHEMBL1793861C56H68ClN13O9S21166.8114 / 122.6No
290102D structureCHEMBL282129C42H51N3O5677.8867 / 36.0No
4428532D structureCHEMBL3349508C66H78ClN11O101220.8712 / 136.6No
305422D structureCHEMBL1793962C66H78ClN11O101220.8712 / 136.6No
4428612D structureCHEMBL3349506C66H78ClN11O101220.8712 / 136.6No
305492D structureCHEMBL1793960C66H78ClN11O101220.8712 / 136.6No
307462D structureCHEMBL236609C28H31FN4442.5824 / 16.4No
309162D structureCHEMBL3122125C82H126N22O27S21916.1635 / 26-14.6No
314262D structureCHEMBL3665845C27H25ClFN3O4509.9627 / 12.6No
338682D structureCHEMBL437448C54H66Br2N12O8S21235.1313 / 114.1No
348462D structureCHEMBL426072C25H25N5S427.574 / 24.6Yes
355612D structureCHEMBL3665764C28H29ClF2N8O2583.0419 / 14.3No
362702D structureCHEMBL502219C59H70ClN13O10S21220.8614 / 143.2No
362922D structureCHEMBL442605C28H35N5O3489.624 / 42.3Yes
363242D structureCHEMBL3639647C28H25ClF3N3O4559.979 / 13.1No
373892D structureCHEMBL1794043C60H71N13O9S21182.4314 / 123.3No

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