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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameMetabotropic glutamate receptor 7
SpeciesRattus norvegicus (Rat)
GeneGrm7
SynonymGLUR7
glutamate receptor
GPRC1G
mGlu7 receptor
mGlu7a receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length915
Amino acid sequenceMVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI
UniProtP35400
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3879
IUPHAR295
DrugBankN/A

Known ligands

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Total entries: 116
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
11092D structureCHEMBL604891C22H20N2O3360.4134 / 04.1Yes
5573542D structureUS9212196, Derivative 9C13H16Cl2NO8P416.1449 / 5-2.6Yes
5359672D structureCHEMBL3974450C13H16Cl2NO8P416.1449 / 5-2.6Yes
5576062D structureUS9212196, Derivative 29C14H20NO8P361.2879 / 5-3.4Yes
5362812D structureCHEMBL3967637C14H20NO8P361.2879 / 5-3.4Yes
129072D structureVU 0361737C13H11ClN2O2262.6933 / 12.6Yes
133212D structureQUISQUALIC ACIDC5H7N3O5189.1276 / 3-3.9Yes
218742D structureCHEMBL595825C20H16N2O2316.363 / 03.7Yes
228432D structureCHEMBL592956C18H13N3O2303.3214 / 02.2Yes
5365732D structureLSP4-2022C13H18NO8P347.269 / 5-3.8Yes
5222662D structureCHEMBL3786667C8H11NO6217.1777 / 4-4.0Yes
5222732D structureCHEMBL3787264C8H11NO6217.1777 / 4-4.0Yes
5222772D structureCHEMBL3786026C8H11NO6217.1777 / 4-4.0Yes
5222892D structureCHEMBL3786938C8H11NO6217.1777 / 4-4.0Yes
255642D structureCHEMBL596274C18H13N3O2303.3214 / 02.2Yes
335182D structureCHEMBL2179631C28H27NO5457.5265 / 14.8Yes
336702D structureCHEMBL603652C21H18N2O2330.3873 / 04.1Yes
366902D structureCID 57689797C3H8NO6P185.0726 / 3-4.5Yes
5584212D structureUS9212196, Derivative 32C14H17F3NO8P415.25812 / 4-2.1No
5369372D structureCHEMBL3910941C14H17F3NO8P415.25812 / 4-2.1No
5369612D structureCHEMBL3898023C14H19FNO9P395.27611 / 5-3.8No
5584422D structureUS9212196, Derivative 6C14H19FNO9P395.27611 / 5-3.8No
428582D structureCHEMBL1089515C7H14NO6P239.1647 / 4-4.8Yes
5370832D structureCHEMBL3969216C14H19ClNO9P411.72810 / 5-3.2Yes
5586012D structureUS9212196, Derivative 7C14H19ClNO9P411.72810 / 5-3.2Yes
5534692D structureADX-71743C17H19NO2269.3443 / 03.8Yes
5199562D structureD-AP4C4H10NO5P183.16 / 4-5.5Yes
572822D structureL-AP4C4H10NO5P183.16 / 4-5.5Yes
5374992D structureCHEMBL3980977C14H17F3NO7P399.25911 / 4-2.4No
5592192D structureUS9212196, Derivative 33C14H17F3NO7P399.25911 / 4-2.4No
637722D structureCHEMBL594648C20H15FN2O3350.3495 / 03.4Yes
668442D structureCHEMBL596305C20H16N2O2316.363 / 03.7Yes
5594772D structureUS9212196, Derivative 19C15H22NO9P391.31310 / 5-3.5Yes
5376872D structureCHEMBL3941586C15H22NO9P391.31310 / 5-3.5Yes
822732D structureCHEMBL3298273C15H13FN2O2272.2794 / 12.1Yes
850692D structureCHEMBL1076865C7H13ClNO6P273.6067 / 4-4.1Yes
971892D structureCHEMBL596275C18H13N3O2303.3214 / 02.3Yes
1093072D structure(2S,1'S,2'S)-2-(carboxycyclopropyl)glycineC6H9NO4159.1415 / 3-3.4Yes
5387352D structureCHEMBL3912541C15H22NO8P375.3149 / 5-3.1Yes
5607992D structureUS9212196, Derivative 10C15H22NO8P375.3149 / 5-3.1Yes
5388812D structureCHEMBL3927149C14H18NO10P391.26911 / 6-4.3No
5609462D structureUS9212196, Derivative 23C14H18NO10P391.26911 / 6-4.3No
5388972D structureCHEMBL3913188C14H19FNO8P379.27710 / 4-3.2Yes
5609612D structureUS9212196, Derivative 34C14H19FNO8P379.27710 / 4-3.2Yes
1284472D structureL-PHOSPHINOTHRICINC5H12NO4P181.1285 / 3-5.0Yes
1303252D structuredemethylphosphinothricinC4H10NO4P167.1015 / 3-5.1Yes
1350072D structure(S)-3,4-DCPGC10H9NO6239.1837 / 4-2.7Yes
1356752D structureCHEMBL594223C21H19N3O2345.4024 / 03.4Yes
5615242D structureUS9212196, Derivative 28C13H16F2NO8P383.24111 / 5-3.6No
5394212D structureCHEMBL3896442C13H16F2NO8P383.24111 / 5-3.6No
5394542D structureCHEMBL3905370C13H18NO7PS363.3219 / 5-3.3Yes
5615542D structureUS9212196, Derivative 26C13H18NO7PS363.3219 / 5-3.3Yes
5397992D structureCHEMBL3982807C15H22NO10P407.31211 / 5-3.9No
5619312D structureUS9212196, Derivative 4C15H22NO10P407.31211 / 5-3.9No
1582902D structure(RS)-PPGC8H10NO5P231.1446 / 4-3.7Yes
1841052D structureCHEMBL595840C19H14N2O2302.3333 / 03.3Yes
1858182D structureMGS-0039C15H14Cl2FNO5378.1777 / 3-0.7Yes
1870132D structureCHEMBL140197C6H9NO5175.146 / 4-3.9Yes
1892252D structureMLS003171619C21H16ClN3O3393.8274 / 12.6Yes
1892332D structureCHEMBL2373733C21H16ClN3O3393.8274 / 12.6Yes
5409242D structureML182C21H16ClN3O3393.8274 / 12.6Yes
5410052D structureCHEMBL3935255C14H20NO9P377.28610 / 5-3.9Yes
5633272D structureUS9212196, Derivative 3C14H20NO9P377.28610 / 5-3.9Yes
1956162D structureCHEMBL594448C20H13F3N2O2370.3316 / 04.2Yes
1984572D structureCHEMBL592954C20H16N2O3332.3594 / 03.3Yes
2010272D structureDcg-IVC7H9NO6203.157 / 4-4.3Yes
2136372D structureVU0366037-2C19H13Cl2N3O2386.2323 / 24.1Yes
5507202D structureCHEMBL3894544C12H19NO9P2383.2310 / 6-5.2No
5644612D structureUS9212196, Derivative 14C12H19NO9P2383.2310 / 6-5.2No
2300922D structureCHEMBL595388C22H20N2O2344.4143 / 04.6Yes
5421002D structureCHEMBL3890165C14H17F3NO9P431.25713 / 5-2.7No
5645512D structureUS9212196, Derivative 20C14H17F3NO9P431.25713 / 5-2.7No
2355872D structureCHEMBL315268C8H12N2O4200.1945 / 3-2.9Yes
2356022D structureCHEMBL262416C8H12N2O4200.1945 / 3-2.9Yes
5422982D structureCHEMBL3966924C14H19N2O11P422.28312 / 5-4.0No
5647532D structureUS9212196, Derivative 5C14H19N2O11P422.28312 / 5-4.0No
2513172D structureCHEMBL399603C20H14N2O4346.3425 / 03.1Yes
2573532D structureMMPIPC19H15N3O3333.3475 / 02.2Yes
5545572D structureLSP1-2111C12H17N2O9P364.24710 / 5-3.4Yes
5430332D structureCHEMBL3909874C14H19ClNO8P395.7299 / 4-2.7Yes
5655212D structureUS9212196, Derivative 35C14H19ClNO8P395.7299 / 4-2.7Yes
2660032D structureCHEMBL592957C21H19N3O2345.4024 / 03.4Yes
2749172D structureCHEMBL399602C20H16N2O3332.3594 / 03.3Yes
5660522D structureBDBM50314796C7H12NO6P237.1487 / 4-2.1Yes
2923252D structureCHEMBL2179629C24H18ClNO4S451.9215 / 15.3No
3105652D structureCHEMBL243925C4H10NO4PS199.1616 / 4-3.8Yes
3108892D structureCHEMBL606137C20H15BrN2O3411.2554 / 04.0Yes
3239162D structure61350-00-3C12H9ClN2O232.6672 / 12.6Yes
3299642D structure479077-09-3C20H16N2O3332.3594 / 03.3Yes
5677042D structureUS9212196, Derivative 21C14H17F3NO8P415.25812 / 5-3.0No
5449562D structureCHEMBL3918221C14H17F3NO8P415.25812 / 5-3.0No
5450442D structureCHEMBL3896848C13H17N2O10P392.25711 / 5-4.0No
5677592D structureUS9212196, Derivative 24C13H17N2O10P392.25711 / 5-4.0No
5453082D structureCHEMBL3895668C13H18NO9P363.25910 / 6-4.2No
5680572D structureUS9212196, Derivative 22C13H18NO9P363.25910 / 6-4.2No
3486392D structureMLS003171622C22H16ClN3O3405.8384 / 13.1Yes
3523702D structureCHEMBL595826C19H13FN2O2320.3234 / 03.4Yes
4558252D structureCHEMBL3427499C5H9FNO5P213.1017 / 4-5.0Yes
3583552D structure201943-63-7C20H19NO5353.3746 / 3-0.2Yes
3736582D structureD-glutamic acidC5H9NO4147.135 / 3-3.7Yes

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