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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProstaglandin F2-alpha receptor
SpeciesBos taurus (Bovine)
GenePTGFR
SynonymProstanoid FP receptor
PGF2-alpha receptor
PGF receptor
DiseaseN/A for non-human GPCRs
Length362
Amino acid sequenceMSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST
UniProtP37289
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4820
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 61
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
303862D structureCHEMBL433752C22H29ClO6424.9186 / 33.1Yes
303882D structureCHEMBL183193C22H29ClO6424.9186 / 33.1Yes
736292D structure16-phenoxy tetranor Prostaglandin F2alphaC22H30O6390.4766 / 42.1Yes
787442D structureCHEMBL88275C25H36O5416.5585 / 43.6Yes
787462D structureCHEMBL2114230C25H36O5416.5585 / 43.6Yes
831292D structure17-phenyl-trinor-PGE2C23H30O5386.4885 / 32.8Yes
961252D structureLanatoprostC26H40O5432.6015 / 34.3Yes
961302D structureCHEMBL364375C26H40O5432.6015 / 34.3Yes
961392D structure15(S)-LatanoprostC26H40O5432.6015 / 34.3Yes
1002442D structure15(R)-Prostaglandin E1C20H34O5354.4875 / 33.2Yes
1002672D structure8-iso Prostaglandin E1C20H34O5354.4875 / 33.2Yes
1098092D structureN-NitrosodithiazineC3H6N2OS2150.2145 / 01.6Yes
1172512D structureCHEMBL489109C21H29ClO7428.9067 / 42.1Yes
1172532D structureCHEMBL491474C21H29ClO7428.9067 / 42.1Yes
1195532D structureLatanoprost acidC23H34O5390.525 / 43.1Yes
1195552D structure5-trans Latanoprost (free acid)C23H34O5390.525 / 43.1Yes
1271762D structureCHEMBL491475C21H30O7394.4647 / 41.4Yes
1271772D structureCHEMBL523143C21H30O7394.4647 / 41.4Yes
1392592D structureBDBM85347C25H37N3O5459.5876 / 41.7Yes
1413792D structureCHEMBL184249C22H30O6390.4766 / 32.5Yes
1413802D structureCHEMBL363946C22H30O6390.4766 / 32.5Yes
1428792D structureCHEMBL1910324C45H71N13O131002.1416 / 15-5.8No
1507702D structure17-Phenyl trinor Pgf2alpha-IprC26H38O5430.5855 / 33.8Yes
1735632D structureCHEMBL422242C26H38O5430.5855 / 33.9Yes
1735642D structureCHEMBL2114229C26H38O5430.5855 / 33.9Yes
1936212D structure5-trans U-46619C21H34O4350.4994 / 23.9Yes
1936262D structureU-46619C21H34O4350.4994 / 23.9Yes
2000892D structureCHEMBL185466C23H29F3O6458.4749 / 33.4Yes
2000922D structureCHEMBL186192C23H29F3O6458.4749 / 33.4Yes
2036332D structureCHEMBL2114224C23H30IN3O5555.4137 / 44.3No
2036342D structureCHEMBL90450C23H30IN3O5555.4137 / 44.3No
2077882D structureCHEMBL185484C26H35F3O6500.5559 / 34.1No
2134112D structureCHEMBL88974C23H31N3O5429.5177 / 43.6Yes
2420662D structureCHEMBL315519C23H31N3O6445.5168 / 53.3Yes
2437602D structureCHEMBL273444C22H30O6390.4766 / 32.5Yes
2437622D structureCHEMBL182117C22H30O6390.4766 / 32.5Yes
2685712D structureAC1L1FGWC23H28O6400.4716 / 21.3Yes
2712262D structureCHEMBL12114C20H34O5354.4875 / 42.7Yes
2712322D structure8-Iso-15(R)-prostaglandin F2alphaC20H34O5354.4875 / 42.7Yes
2712382D structureMLS003107056C20H34O5354.4875 / 42.7Yes
2712452D structuredinoprostC20H34O5354.4875 / 42.7Yes
2721722D structureCHEMBL422418C22H29N3O7447.4889 / 52.6Yes
3280882D structure87893-54-7C20H30O4334.4564 / 23.9Yes
3293612D structureCHEMBL264554C19H32O5340.465 / 32.6Yes
3293632D structureCHEMBL360869C19H32O5340.465 / 32.6Yes
3433702D structure60325-46-4C23H31NO7S465.5617 / 31.5Yes
3564992D structurecloprostenolC22H29ClO6424.9186 / 42.7Yes
3565062D structure7-{2-[4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoic acidC22H29ClO6424.9186 / 42.7Yes
3707782D structureCHEMBL184264C22H29ClO6424.9186 / 33.1Yes
3707802D structureCHEMBL360862C22H29ClO6424.9186 / 33.1Yes
3842152D structure(+)-fluprostenolC23H29F3O6458.4749 / 42.9Yes
3901122D structureProstaglandin E2C20H32O5352.4715 / 32.8Yes
3901272D structure8-iso PROSTAGLANDIN E2C20H32O5352.4715 / 32.8Yes
3951572D structureCHEMBL521964C23H31F3O6460.499 / 43.0Yes
3951592D structureCHEMBL491667C23H31F3O6460.499 / 43.0Yes
4035232D structureUnoprostone isopropyl esterC25H44O5424.6225 / 24.9Yes
4044612D structure69552-46-1C21H34O4350.4994 / 33.2Yes
4044752D structurecarbacyclinC21H34O4350.4994 / 33.2Yes
4182002D structureCHEMBL363439C23H29F3O6458.4749 / 33.4Yes
4182022D structureCHEMBL185559C23H29F3O6458.4749 / 33.4Yes
4229842D structureBW A868CC25H37N3O5459.5876 / 31.7Yes

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