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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NamePituitary adenylate cyclase-activating polypeptide type I receptor
SpeciesHomo sapiens (Human)
GeneADCYAP1R1
SynonymPACAPR1
pituitary adenylate cyclase activating polypeptide 1 receptor (1)
PACAP1-R
PACAP-R1
PACAP-R-1
[ Show all ]
DiseaseN/A
Length468
Amino acid sequenceMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
UniProtP41586
Protein Data Bank3n94
GPCR-HGmod modelP41586
3D structure modelThis structure is from PDB ID 3n94.
BioLiPBL0183307
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5399
IUPHAR370
DrugBankN/A

Known ligands

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Total entries: 122
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5152D structureCID 44566179C205H333N63O53S4560.3767 / 71-16.3No
37712D structure[Sar4]PACAP38C204H333N63O53S4548.3667 / 67-17.9No
59672D structure[Glu3]PACAP38C204H333N63O53S4548.3667 / 68-17.8No
153992D structureCHEMBL255635C22H17ClN4O2404.8544 / 23.7Yes
5221452D structureCHEMBL3775436C15H26ClNO3303.8274 / 3N/AN/A
5221682D structureCHEMBL3775769C15H26ClNO3303.8274 / 3N/AN/A
235242D structureCHEMBL444343C26H28N2O5448.5196 / 25.0Yes
235682D structureBDBM81535C182H300N56O45S4024.8158 / 60-13.3No
250002D structureCHEMBL404071C22H16ClF3N2O3448.8267 / 25.5No
272102D structureCHEMBL2203713C18H22N4S326.4624 / 22.9Yes
329622D structureCHEMBL270785C21H17ClN2O3380.8284 / 24.6Yes
369102D structure[Ala2]PACAP38C203H331N63O52S4518.3366 / 67-17.1No
380932D structureCHEMBL256636C22H16ClF3N2O3448.8267 / 25.5No
393762D structureCID 44139716C141H222N40O38S3117.6346 / 47-9.7No
401212D structureCHEMBL256837C22H16ClF3N2O3448.8267 / 25.5No
465192D structure[N-Me-Asp3]PACAP38C204H333N63O53S4548.3667 / 67-17.9No
5535732D structureMK 0893C32H27Cl2N3O4588.4855 / 26.8No
652552D structureCID 44566139C143H226N40O39S3161.6847 / 47-10.2No
762872D structureCHEMBL409325C26H27ClN2O5482.9616 / 25.6No
834532D structureCID 44566138C204H333N63O53S4548.3667 / 71-16.4No
844032D structure[N-Me-Thr7]PACAP38C204H333N63O53S4548.3667 / 67-17.9No
889752D structureCID 44139713C139H222N38O39S3081.5946 / 47-10.1No
939022D structureCID 16214685C142H223N39O40S3148.6448 / 48-12.0No
5242952D structureSCHEMBL2101506C21H20ClFN2O4418.8495 / 32.3Yes
1007282D structure[N-Me-Phe6]PACAP38C204H333N63O53S4548.3667 / 67-17.9No
1061962D structure[Cha6]PACAP38C203H337N63O53S4540.3867 / 68-17.0No
1105672D structureCID 44566184C204H331N63O53S4546.3467 / 71-16.7No
1196472D structureCHEMBL152640C28H26N4O2450.5424 / 25.9No
1218262D structureCHEMBL1187422C144H228N40O39S3175.7147 / 48-9.8No
1240042D structureCID 44566171C144H226N40O38S3157.6946 / 46-9.0No
1240052D structureCID 44139868C144H226N40O38S3157.6946 / 46-9.0No
1249002D structureCID 44139848C148H228N40O39S3223.7547 / 48-8.7No
1288272D structure[Glu3]PACAP27C143H226N40O39S3161.6847 / 46-10.7No
1295222D structureCID 44566151C204H333N63O53S4548.3667 / 71-16.7No
1318832D structureCID 44566161C142H224N40O40S3163.6548 / 49-10.7No
1324232D structureCHEMBL1644183C27H20Cl2F3N3O4578.3698 / 26.4No
1425922D structure[Bip6]PACAP38C209H335N63O53S4610.4367 / 68-16.5No
1523292D structureCHEMBL153038C26H24ClN3O2445.9473 / 25.9No
1642652D structure[Aib2]PACAP27C143H226N40O38S3145.6846 / 45-9.9No
1675222D structureCID 44566159C142H230N40O39S3153.747 / 48-9.2No
1841362D structure[Ala1]PACAP38C200H329N61O53S4468.2766 / 67-17.9No
1921142D structureCID 44139855C142H222N40O39S3145.6447 / 47-10.9No
1962442D structure[Asn3]PACAP38C203H332N64O52S4533.3566 / 68-16.5No
1978152D structureCID 44566174C204H333N63O52S4532.3666 / 71-15.4No
1985812D structure[N-Me-Ile5]PACAP38C204H333N63O53S4548.3667 / 67-17.9No
1996352D structureCID 44139863C143H226N40O39S3161.6847 / 47-10.2No
2108352D structure[Ala7]PACAP38C202H329N63O52S4504.366 / 67-17.5No
2112262D structureCID 44139849C144H226N40O39S3173.6947 / 47-10.0No
2195322D structure[Ala4]PACAP38C204H333N63O53S4548.3667 / 68-17.7No
2243222D structureCHEMBL2206397C14H18N2214.3121 / 13.6Yes
2292212D structureCID 44566137C143H226N40O39S3161.6847 / 47-10.2No
2296062D structureAc-PACAP27C144H226N40O40S3189.6947 / 46-10.8No
2309472D structureCHEMBL444801C27H30N2O6478.5457 / 25.0Yes
2354222D structure[Aad3]PACAP38C205H335N63O53S4562.3867 / 68-17.4No
2431332D structureCID 44566141C143H226N40O39S3161.6847 / 47-10.2No
2437562D structureCID 44566181C143H224N40O39S3159.6747 / 47-10.6No
2504422D structureCID 44566120C200H325N63O53S4492.2567 / 72-17.9No
2529912D structureCHEMBL409729C24H20ClF3N2O5508.8789 / 25.4No
2533272D structureCHEMBL270226C27H29ClN2O5496.9886 / 26.0No
2546152D structureCHEMBL257706C24H22ClN3O5467.9066 / 33.8Yes
2573772D structureCID 44566183C143H224N40O39S3159.6747 / 47-10.4No
2578722D structureCID 44139844C143H226N40O39S3161.6847 / 47-10.4No
5290412D structureCHEMBL3736134C150H227FN40O39S3265.7648 / 48-8.2No
2629152D structureCHEMBL402430C30H24ClN3O3509.994 / 26.2No
2674212D structureAc-PACAP38C205H333N63O54S4576.3767 / 68-17.9No
2819102D structureCID 44566147C143H226N40O39S3161.6847 / 47-10.2No
2910032D structureCID 44566153C142H225N41O38S3146.6746 / 48-8.7No
2999692D structureCHEMBL255824C22H16ClF3N2O3448.8267 / 25.5No
3030562D structureCID 44566182C204H331N63O53S4546.3467 / 71-16.8No
3087012D structure[D-Asp3]PACAP27C142H224N40O39S3147.6647 / 46-11.1No
3087022D structure[D-Ser2]PACAP27C142H224N40O39S3147.6647 / 46-11.1No
3087032D structureCID 44139860C142H224N40O39S3147.6647 / 48-10.3No
3087042D structureCID 44566125C142H224N40O39S3147.6647 / 48-10.3No
3087052D structureCID 44566133C142H224N40O39S3147.6647 / 48-10.3No
3087062D structurePACAP 1-27C142H224N40O39S3147.6647 / 48-10.3No
5547922D structurepituitary adenylate cyclase activating polypeptide-27C142H224N40O39S3147.6647 / 48-10.3No
3087132D structureCID 44139861C142H224N40O39S3147.6647 / 48-10.3No
3107252D structureCID 44566162C203H331N63O54S4550.3368 / 73-17.0No
3172092D structure[Ala2]PACAP27C142H224N40O38S3131.6646 / 45-10.1No
3200892D structureCHEMBL272118C21H17ClN2O3380.8284 / 24.6Yes
3205542D structureCHEMBL256880C23H18ClN3O2403.8663 / 24.8Yes
3303072D structureCHEMBL2087421C24H40N4O5S496.6678 / 01.6Yes
5309222D structureCHEMBL3736230C150H228N40O39S3247.7747 / 48-8.3No
3358032D structureCID 44566130C203H331N63O53S4534.3367 / 72-16.6No
3358042D structureCID 44566134C203H331N63O53S4534.3367 / 72-16.6No
3358052D structure[D-His1]PACAP38C203H331N63O53S4534.3367 / 68-18.1No
3358062D structure[D-Ile5]PACAP38C203H331N63O53S4534.3367 / 68-18.1No
3358072D structure[D-Ser2]PACAP38C203H331N63O53S4534.3367 / 68-18.1No
3358082D structureAKOS024456450C203H331N63O53S4534.3367 / 72-16.6No
3358102D structure[D-Thr7]PACAP38C203H331N63O53S4534.3367 / 68-18.1No
3383702D structure[Ind6]PACAP27C142H222N40O39S3145.6447 / 45-11.3No
3423022D structureCID 44139714C141H224N40O37S3103.6545 / 47-7.2No
3423062D structureCID 44566155C144H228N40O39S3175.7147 / 48-9.6No
3423312D structureCID 44566119C139H218N40O39S3105.5747 / 48-11.7No
3457332D structure[N-Me-Ile5]PACAP27C143H226N40O39S3161.6847 / 45-10.9No
3461132D structureCHEMBL270784C25H24ClN3O6497.9327 / 33.7Yes
5550412D structureBDBM81828C147H237N43O43S3326.8351 / 49-16.6No
3532732D structureCID 44566117C143H226N40O39S3161.6847 / 48-9.9No
3577932D structureCHEMBL269990C23H18ClF3N2O4478.8528 / 25.4No
3654002D structure[His(1-Me)1]PACAP27C143H226N40O39S3161.6847 / 45-11.1No

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