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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 1B
SpeciesCricetulus griseus (Chinese hamster)
GeneHTR1B
Synonym5-HT-1B
5-HT1B
Serotonin receptor 1B
DiseaseN/A for non-human GPCRs
Length386
Amino acid sequenceMEEQGIQCAPPPPAASQTGVPLVNLSHNCSAESHIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPVSTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYAAKRTPKRAAIMIALVWVFSISISLPPFFWRQAKAEEEVLTCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTTSVTSINSRAPDLPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMATLDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
UniProtP46636
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3707466
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 54
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
29432D structureSCHEMBL931468C23H26N4O2390.4875 / 03.1Yes
147292D structureSCHEMBL931803C27H26N6O2466.5457 / 13.3Yes
232682D structureSCHEMBL932715C29H32N4O4S532.6597 / 03.7No
288482D structureSCHEMBL932393C27H31FN4O3478.5686 / 03.5Yes
322962D structureSCHEMBL931086C22H25BrN4O2457.3725 / 03.7Yes
376182D structureSCHEMBL930901C23H28N4O3408.5026 / 02.9Yes
396182D structureSCHEMBL943980C27H32N4O3460.5785 / 03.4Yes
426882D structureSCHEMBL3791467C31H35N5O2509.6546 / 15.2No
430342D structureSCHEMBL931445C24H28N4O3420.5136 / 03.4Yes
679592D structureSCHEMBL932014C26H30N6O2458.5666 / 12.9Yes
820212D structureSCHEMBL932198C21H24N4O2364.4495 / 12.8Yes
882292D structureSCHEMBL931928C23H25N5O2403.4866 / 02.7Yes
933452D structureSCHEMBL932678C23H28N4O3408.5026 / 02.9Yes
961622D structureSCHEMBL932078C28H27N5O2465.5576 / 14.0Yes
975992D structureSB 242084C21H19ClN4O2394.8594 / 13.8Yes
1157852D structureSCHEMBL931495C27H30N6O2S502.6378 / 03.9No
1210212D structureSCHEMBL931747C28H30N4O3470.5736 / 14.3Yes
1257782D structureSCHEMBL3782291C26H27N5O2441.5356 / 13.2Yes
1262412D structureSCHEMBL932228C26H32N4O3448.5676 / 13.4Yes
1296252D structureSCHEMBL931161C27H29N5O2455.5626 / 03.4Yes
1318532D structureSCHEMBL931675C28H30N4O3470.5736 / 14.3Yes
1522952D structureSCHEMBL932199C28H32N4O3472.5895 / 03.5Yes
1601422D structureSCHEMBL931519C27H29N5O2455.5626 / 03.4Yes
1634562D structureSCHEMBL932091C22H25FN4O2396.4666 / 03.1Yes
1690012D structureSCHEMBL3787910C28H29N5O2467.5736 / 13.6Yes
1696622D structureSCHEMBL932062C23H25F3N4O2446.4748 / 03.9Yes
1767512D structureSCHEMBL931797C29H32N4O4S532.6597 / 13.5No
1813892D structureSCHEMBL931121C28H29N5O3483.5727 / 03.4Yes
1899082D structureSCHEMBL931922C22H25FN4O2396.4666 / 03.1Yes
2079092D structureSCHEMBL931632C22H26N4O2378.4765 / 03.0Yes
2182732D structureSCHEMBL932470C26H28N6O2456.557 / 13.0Yes
2306852D structureSCHEMBL931521C23H28N4O3408.5026 / 02.9Yes
2323522D structureSCHEMBL3791937C31H36N6O3540.6688 / 14.4No
2380402D structureSCHEMBL931597C24H26F2N4O2440.4957 / 14.0Yes
5286012D structureSCHEMBL931452C28H31N5O2469.5896 / 14.0Yes
2550252D structureSCHEMBL931619C27H28N4O3456.5466 / 23.9Yes
3105262D structureSCHEMBL3790615C30H33ClN6O2545.0847 / 15.1No
3173422D structureSCHEMBL3785805C28H30N4O4S518.6327 / 13.5No
3307132D structureSCHEMBL932656C27H30N6O2470.5777 / 13.5Yes
3375482D structureSCHEMBL931976C23H26N4O2390.4875 / 13.3Yes
3385312D structureSCHEMBL932193C25H28N6O2444.5396 / 12.4Yes
3489312D structureSCHEMBL932148C23H28N4O2392.5035 / 03.3Yes
3560022D structureSCHEMBL931392C23H28N4O3408.5026 / 03.3Yes
3623782D structureSCHEMBL931585C28H27N5O2465.5576 / 14.0Yes
3712662D structureSCHEMBL3787659C27H33N5O3475.5936 / 12.8Yes
3751672D structureSCHEMBL931714C24H29N5O3435.5286 / 12.2Yes
3754362D structureSCHEMBL931141C28H28N4O4484.5567 / 14.1Yes
3926642D structureSCHEMBL931346C26H27N5O2441.5356 / 13.3Yes
5327262D structureSCHEMBL943679C26H30N6O2458.5666 / 13.0Yes
4028442D structureSCHEMBL3785037C30H33N5O3511.6267 / 14.1No
4043012D structureSCHEMBL931549C29H32N4O3484.66 / 14.7Yes
4118942D structureSCHEMBL931509C24H28N4O3420.5136 / 02.7Yes
5337112D structureSCHEMBL3777493C27H29N5O2455.5626 / 13.7Yes
4400682D structureSCHEMBL931520C24H28N4O2404.5145 / 03.5Yes

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