Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

GPCR

NameCannabinoid receptor 1
SpeciesMus musculus (Mouse)
GeneCnr1
SynonymSKR6R
Neuronal cannabinoid receptor
Central cannabinoid receptor
CB1R
CB1 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length473
Amino acid sequenceMKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
UniProtP47746
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3037
IUPHAR56
DrugBankN/A

Known ligands

You can:

Total entries: 277
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
11822D structureCHEMBL3290443C21H18Cl2N4O3445.35 / 14.8Yes
20842D structureCHEMBL224114C26H20Cl3N3O496.8162 / 17.8No
20902D structureCHEMBL225622C25H24Cl3N3O488.8372 / 17.7No
35842D structureCHEMBL2380424C25H25NO2371.482 / 05.7No
49132D structure(2E,4E)-N-isobutyltetradeca-2,4-dienamideC18H33NO279.4681 / 16.6No
52222D structureCHEMBL225415C24H24Cl2N4O455.3833 / 16.3No
5216202D structureOrg 27569C24H28ClN3O409.9582 / 26.0No
75842D structureCHEMBL217247C23H36N4O3416.5666 / 22.2Yes
4420452D structure335161-24-5C24H22FNO359.4442 / 05.9No
87382D structureCHEMBL2380407C20H21NO3323.3923 / 23.8Yes
4420562D structureCHEMBL3331449C22H24N4OS392.5214 / 14.3Yes
5362142D structureCHEMBL3984538C31H36ClN3O502.0992 / 17.9No
103932D structureCHEMBL2022405C23H16Cl3N3O2472.753 / 26.6No
104252D structureCHEMBL218957C22H19Cl3N4O461.7713 / 16.1No
125632D structurePiperidine, 1-[(2E,4E)-1-oxo-2,4-tetradecadienyl]-C19H33NO291.4791 / 06.3No
134622D structureCHEMBL2380412C22H24FNO337.4382 / 05.4No
135972D structureCHEMBL2380411C21H22FNO2339.413 / 04.5Yes
152782D structureCHEMBL2380418C21H22FNO2339.413 / 04.5Yes
167552D structure362519-49-1C23H20Cl2N4O2S487.3994 / 15.3No
177312D structureCHEMBL409150C24H20Cl2F2N4O489.3484 / 16.4No
197872D structureUNII-5F4WO3BVS9C16H29NO251.4141 / 15.5No
281342D structureCHEMBL385508C21H28N4O3384.486 / 11.2Yes
290682D structureCHEMBL393324C23H18ClN3O3S451.9255 / 14.2Yes
5534212D structure[123I]AM251C22H21Cl2IN4O551.2433 / 16.5No
344672D structureCHEMBL225377C25H18Cl3N3O482.7892 / 17.4No
4431152D structureCHEMBL3526290C24H21NO3371.4363 / 14.7Yes
392762D structureCHEMBL2442635C16H21NOS275.412 / 14.3Yes
393822D structureCHEMBL494376C23H23BrN4O2467.3675 / 04.1Yes
417502D structureCHEMBL216382C24H26FN3O2407.4895 / 14.5Yes
429522D structureCHEMBL2380423C20H21NO2307.3932 / 14.1Yes
447812D structureCHEMBL2338175C22H29NO2339.4792 / 04.0Yes
449972D structureCHEMBL494603C21H22N4O2S394.4936 / 03.2Yes
459172D structureCHEMBL3290449C27H27Cl2N3O2496.4323 / 17.9No
459912D structureCHEMBL541216C24H23Cl3N4O489.8253 / 17.0No
460992D structureCHEMBL521685C23H23ClN4O2422.9135 / 04.1Yes
472352D structureCHEMBL120935C24H41NO2375.5972 / 26.4No
484222D structureCHEMBL1210154C19H16N2O2S336.4094 / 14.7Yes
484912D structureSCHEMBL4318956C19H16N2O2S336.4094 / 14.7Yes
495542D structureCHEMBL385268C24H17Cl2N3O434.322 / 16.3No
498152D structureCHEMBL217549C24H26FN3O2407.4895 / 14.5Yes
503462D structureCHEMBL241567C27H30ClN3O3S512.0655 / 15.6No
538482D structureDronabinolC21H30O2314.4692 / 17.0No
5373222D structure17766-02-8C21H30O2314.4692 / 17.0No
538562D structureTHC, delta 9C21H30O2314.4692 / 17.0No
548802D structureCHEMBL3286437C21H18Cl2N4O2429.3014 / 15.7No
599672D structureCHEMBL2442643C19H31NO289.4631 / 05.3No
5341972D structureCHEMBL3899761C23H21NO2343.4262 / 15.4No
4707162D structureCHEMBL3633034C24H15Cl3F3N3O524.7495 / 17.9No
663962D structureCHEMBL217583C22H21ClFN3O2413.8775 / 14.8Yes
681442D structureCHEMBL386489C22H22FN3O2379.4355 / 13.9Yes
5378502D structureCHEMBL3924830C31H36ClN3O502.0992 / 17.9No
783942D structure4-cyanophenyl ethyl dodecylphosphonateC21H34NO3P379.4814 / 07.0No
5342562D structureJWH 073 N-(4-hydroxybutyl) metaboliteC23H21NO2343.4262 / 14.6Yes
827782D structureGP 1AC23H22Cl2N4O441.3563 / 15.9No
829532D structureCHEMBL120944C28H48FNO433.6962 / 19.5No
832492D structureCHEMBL386858C24H15Cl4N3O503.2042 / 17.6No
852202D structureCHEMBL239257C16H28N4O3S356.4856 / 12.6Yes
874752D structureCHEMBL224847C25H17Cl4N3O517.2312 / 18.1No
875472D structureCHEMBL112486C20H33FO2S356.543 / 07.1No
889622D structureCHEMBL219037C25H16Cl2F3N3O502.3185 / 17.2No
898852D structureCHEMBL385057C23H28FN3O2397.4945 / 23.9Yes
901372D structureCHEMBL217266C24H27N3O2389.4994 / 14.1Yes
922712D structureCHEMBL389203C23H21Cl3N4O475.7983 / 16.4No
964632D structureCHEMBL120788C26H44FNO405.6422 / 18.6No
1005992D structureCHEMBL120473C27H46FNO419.6692 / 18.9No
1031832D structureJTE 907C24H26N2O6438.486 / 24.4Yes
1044452D structureCHEMBL2338179C19H23NO281.3991 / 03.4Yes
5385522D structureCHEMBL3917142C26H26Cl3N3O502.8642 / 18.3No
4458302D structureJD-5037C27H27Cl2N5O3S572.5055 / 25.7No
4458942D structureCHEMBL3329245C28H33N3OS459.6523 / 16.5No
1074722D structureCHEMBL224609C25H26Cl2N4O469.413 / 16.7No
1079222D structureCHEMBL386725C22H22ClN3O2395.8874 / 14.7Yes
1111022D structureCHEMBL464679C21H30O2314.4692 / 15.7No
1141252D structureCHEMBL2442636C15H19NOS261.3832 / 14.0Yes
1187452D structureCHEMBL309042C23H38FNO363.5612 / 17.0No
1188902D structureoctane-1-sulfonyl fluorideC8H17FO2S196.283 / 03.6Yes
1191872D structureCHEMBL216335C24H17Cl2N5O3494.3325 / 26.5No
1202442D structureCID 71580904C23H22ClN3O391.8993 / 15.2No
1217752D structureWin-55212-2C27H26N2O3426.5164 / 04.4Yes
1291922D structureCHEMBL240109C24H24Cl3N3O3S540.8845 / 16.0No
1332142D structureCHEMBL2338187C18H21NO267.3721 / 03.5Yes
1383042D structureCHEMBL2442637C16H19NOS273.3942 / 03.7Yes
1402572D structuremethyl icosylphosphonofluoridateC21H44FO2P378.5533 / 09.9No
1429982D structureSCHEMBL2736941C22H34N2O2358.5262 / 14.8Yes
1442902D structureCHEMBL387112C26H20Cl3N3O2512.8153 / 17.4No
1463712D structureCHEMBL494395C24H26N4O2402.4985 / 03.7Yes
1470442D structureCHEMBL121258C25H43NO2389.6242 / 26.7No
1470672D structureCHEMBL2380429C26H26N2O3414.5054 / 04.2Yes
1473142D structureCHEMBL517157C23H24N4O2388.4715 / 03.4Yes
5397732D structureCHEMBL3889602C30H30Cl3N3O554.942 / 18.8No
1482172D structureCHEMBL2380410C21H22FNO2339.413 / 04.5Yes
4475562D structure1-Pentyl-3-(1-naphthoyl)indoleC24H23NO341.4541 / 06.3No
1496282D structureCHEMBL2380421C20H20FNO2325.3833 / 14.2Yes
1542692D structureCHEMBL3290442C22H20Cl2N4O2443.3284 / 16.0No
1564522D structureCHEMBL495440C28H27N3O3453.5425 / 05.9No
4479352D structureCHEMBL3331457C20H18Cl2N4OS433.3514 / 15.2No
1596032D structureCHEMBL218295C24H27N3O2389.4994 / 14.0Yes
1635812D structureRimonabantC22H21Cl3N4O463.7873 / 16.5No
1636782D structureCHEMBL2380427C23H21NO2343.4262 / 15.4No
4481552D structureCHEMBL3331461C22H21Cl2N3OS446.393 / 16.3No

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218