Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Sphingosine 1-phosphate receptor 2
Species	Rattus norvegicus (Rat)
Gene	S1pr2
Synonym	S1P2 receptor S1P2 S1P receptor Edg-5 S1P receptor 2 GPCR18 Gpcr13 G-protein coupled receptor H218 G protein-coupled receptor 13 Endothelial differentiation G-protein coupled receptor 5 endothelial differentiation G protein-coupled receptor 5 edg5 AGR16 Sphingosine 1-phosphate receptor Edg-5 [ Show all ]
Disease	N/A for non-human GPCRs
Length	352
Amino acid sequence	MGGLYSEYLNPEKVQEHYNYTKETLDMQETPSRKVASAFIIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASVFSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLLCWRQGKGATGRRGGNPGHRLLPLRSSSSLERGLHMPTSPTFLEGNTVV
UniProt	P47752
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3616360
IUPHAR	276
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
517504	CHEMBL3703200	C36H44FN3O6	633.761	7 / 3	6.1	No
469606	CHEMBL3618200	C30H27F2N3O6S	595.618	9 / 3	4.1	No
473047	CHEMBL3618196	C31H27ClFN3O5	576.021	6 / 3	4.9	No
474921	CHEMBL3618189	C19H26F4N2O2	390.423	6 / 2	4.6	Yes
460218	CHEMBL3703202	C33H37FN2O7	592.664	8 / 3	5.9	No
460271	CHEMBL3703201	C30H33FN2O6	536.6	7 / 3	5.3	No
477377	CHEMBL3618199	C31H28F2N2O6S	594.63	8 / 2	4.8	No
482121	CHEMBL3618198	C29H25F2N3O4	517.533	7 / 2	4.5	No
460680	CHEMBL3703204	C25H30F4N2O3	482.52	7 / 2	6.1	No
460994	CHEMBL3703203	C32H37FN2O6	564.654	7 / 3	6.0	No
461289	CHEMBL3703199	C33H40FN3O5	577.697	6 / 3	6.4	No
496524	CHEMBL3618197	C31H27F2N3O5	559.57	7 / 3	4.4	No
461573	CHEMBL3618201	C31H26F2N2O6	560.554	8 / 3	5.0	No
461600	SCHEMBL5912478	C24H31FN2O3	414.521	4 / 2	5.2	No
554759	Jte 013	C17H19Cl2N7O	408.287	5 / 3	4.4	Yes
462229	CHEMBL3703198	C34H39FN2O6	590.692	7 / 3	6.5	No
512550	CHEMBL3401383	C31H36FN3O5	549.643	6 / 3	5.6	No
514509	CHEMBL3618190	C19H17BrF4N2O2	461.255	6 / 2	3.9	Yes

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218