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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 5A
SpeciesHomo sapiens (Human)
GeneHTR5A
Synonym5-HT5alpha
5-HT-5
MR22
Htr5
5-HT-5A
[ Show all ]
DiseaseN/A
Length357
Amino acid sequenceMDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
UniProtP47898
Protein Data BankN/A
GPCR-HGmod modelP47898
3D structure modelThis predicted structure model is from GPCR-EXP P47898.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3426
IUPHAR10
DrugBankBE0004688

Known ligands

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Total entries: 828
Page:  / 9 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
10312D structureCHEMBL2205816C18H20N2O280.3713 / 11.8Yes
14732D structure4365 CTC14H20N2O232.3272 / 12.7Yes
22752D structure1-(cyclohexylmethyl)pyrrolidineC11H21N167.2961 / 03.1Yes
29162D structureCHEMBL446459C14H19F2N3O283.3234 / 22.6Yes
31422D structureAC1N0YGAC3H7NO4S153.1525 / 2-4.7Yes
36792D structureMLS001172392C16H17Cl2N3O338.2323 / 13.3Yes
37152D structureAC1NW0NQC14H13NO4S291.3215 / 02.5Yes
50062D structureCHEMBL130585C21H23N3O3365.4334 / 03.8Yes
55162D structureCHEMBL188440C36H40F3N3O4S667.78810 / 2N/ANo
66212D structureMLS000401592C26H21FN4O5S2552.5959 / 35.1No
4637362D structureCHEMBL3633757C26H24BrNO4494.3855 / 05.4No
5361402D structureCHEMBL3899832C22H19N5O4417.4258 / 23.6Yes
81842D structureCHEMBL186450C34H34F3N3O4605.6589 / 2N/ANo
5216912D structureCHEMBL3754496C16H19FN2258.342 / 12.9Yes
107162D structureCHEMBL3287723C25H32O7444.5247 / 25.7No
116052D structureMLS000735366C21H28N2O3S388.5266 / 03.8Yes
5533082D structurePropranolol, L-C16H21NO2259.3493 / 23.0Yes
119682D structureAlfentanil hydrochlorideC21H33ClN6O3452.9846 / 1N/AN/A
124602D structureCHEMBL338696C22H25FN2O352.4533 / 13.6Yes
136542D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
151262D structure106674-03-7C27H20N2O8S532.5238 / 13.9No
152042D structureCHEMBL3654211C17H14F4N4O366.325 / 22.7Yes
154742D structureCHEMBL2205829C19H19NO3309.3654 / 12.2Yes
155612D structureMLS000731975C24H31N3O2393.5315 / 04.1Yes
157382D structureMLS000731911C23H28FN3OS413.5555 / 04.6Yes
5219542D structureAM-0902C17H15ClN6O2370.7976 / 02.3Yes
163252D structureCHEMBL272752C8H8ClN3181.6231 / 20.8Yes
172482D structureCHEMBL536561C9H12IN3O305.1192 / 3N/AN/A
204022D structureCHEMBL338095C21H22ClFN2O372.8683 / 04.7Yes
208262D structureSMR000211820C23H21N5O2399.4546 / 04.4Yes
218572D structureCHEMBL126737C21H22ClFN2O372.8683 / 04.7Yes
5221112D structureCHEMBL3775436C15H26ClNO3303.8274 / 3N/AN/A
5221642D structureCHEMBL3775769C15H26ClNO3303.8274 / 3N/AN/A
225522D structureCHEMBL283036C19H19F3N4360.3846 / 13.6Yes
231722D structure1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amineC11H16INO2321.1583 / 12.5Yes
242922D structureCHEMBL2181168C21H24IN3O461.3474 / 05.1No
246172D structureSMR000160814C24H18BrN3O4492.3295 / 25.1No
5366182D structure2-ChloroadenosineC10H12ClN5O4301.6878 / 4-0.1Yes
248682D structureMLS000733666C25H29NO3391.5114 / 14.3Yes
5580672D structureMLS000587743C17H13BrF3N3O5476.2069 / 23.8Yes
263082D structureCHEMBL600053C18H18FNO283.3463 / 12.5Yes
5533972D structureYohimbineC21H26N2O3354.454 / 22.9Yes
271922D structureCHEMBL2203713C18H22N4S326.4624 / 22.9Yes
274942D structureCHEMBL2432063C19H29N271.4481 / 04.7Yes
287622D structureCHEMBL320412C17H26N4O2S350.4815 / 21.6Yes
293512D structureSMR000005041C23H33ClN6OS477.0687 / 1N/AN/A
294962D structureMLS001239230C25H31ClF2N4O3S2573.1159 / 1N/ANo
305132D structureMLS000948488C22H18Cl3N3S462.8174 / 1N/AN/A
5482442D structureCHEMBL3959210C14H18ClN5O3339.787 / 30.3Yes
321332D structureaspirinC9H8O4180.1594 / 11.2Yes
325102D structureUNII-QQYOR9S587C18H29NO275.4362 / 04.8Yes
328522D structurePhencyclidine hydrochlorideC17H26ClN279.8521 / 1N/AN/A
334752D structureUNII-7W7511NPF8C20H20N2O3S368.4516 / 11.8Yes
352462D structureHARMINEC13H12N2O212.2522 / 13.6Yes
371902D structureCHEMBL187621C34H38N4O518.7054 / 15.3No
376252D structureCHEMBL103371C17H26N4O2S350.4815 / 11.6Yes
387552D structureMLS001197120C24H20N2O4400.4344 / 24.7Yes
390552D structureCHEMBL126823C21H24N2O320.4362 / 03.9Yes
390742D structureCHEMBL186849C35H45F3N4O3626.7659 / 2N/ANo
396252D structureSMR000176430C25H27Cl2N3O456.4112 / 2N/AN/A
398522D structureMLS002701634C20H12O3300.3133 / 13.6Yes
399202D structureSCHEMBL9104672C18H15FN4O322.3433 / 23.1Yes
402982D structureAripiprazoleC23H27Cl2N3O2448.3884 / 14.6Yes
409692D structure16502-01-5C11H12N2172.2311 / 21.5Yes
410772D structureCHEMBL476838C23H29FN2O5432.4927 / 13.9Yes
415582D structureMLS000720325C17H22N4S314.4513 / 22.4Yes
424672D structureCHEMBL2432039C20H23N277.4111 / 12.7Yes
428192D structureCHEMBL539103C8H9FIN3293.0842 / 3N/AN/A
433272D structureCHEMBL481153C19H20N2O2S340.4414 / 03.9Yes
435902D structureCHEMBL403103C16H22N4O286.3792 / 21.6Yes
440262D structureCHEMBL2432060C21H26FN311.4442 / 04.8Yes
449862D structureCHEMBL3654203C17H17F2N5O345.3544 / 21.9Yes
450492D structureMLS000552833C34H38N4O5582.7015 / 35.0No
454162D structureCHEMBL1275709C16H19N3253.3492 / 12.8Yes
454272D structureCHEMBL3654206C19H17F3N4O374.3674 / 22.9Yes
457762D structure23981-80-8C14H14O3230.2633 / 13.3Yes
474742D structureCHEMBL2432051C21H27NO3341.4514 / 13.3Yes
484442D structureCHEMBL1210154C19H16N2O2S336.4094 / 14.7Yes
4596542D structureSCHEMBL4318956C19H16N2O2S336.4094 / 14.7Yes
490402D structureSCHEMBL9106401C17H11ClF2N4O360.7494 / 23.5Yes
510352D structureSCHEMBL9105330C17H12ClFN4O342.7583 / 23.4Yes
5588952D structureHarmalanC12H12N2184.2421 / 12.1Yes
524652D structureCHEMBL258075C12H17N3O219.2882 / 21.3Yes
525722D structureCHEMBL590615C19H20FNO297.3733 / 13.0Yes
529092D structureCHEMBL1829958C12H9BrN4O305.1354 / 32.3Yes
4695132D structureCHEMBL3609143C29H29NO4455.5545 / 05.4No
537912D structure{4-[(3-fluorophenyl)methoxy]phenyl}methanamine hydrochlorideC14H15ClFNO267.7283 / 2N/AN/A
540752D structureST-1535C12H16N8272.3166 / 11.8Yes
4696202D structureCHEMBL3608451C27H27NO4429.5165 / 05.1No
545392D structureMLS000733242C23H21FN4O388.4465 / 13.4Yes
546892D structureMLS002320705C35H49NO10643.77411 / 51.1No
556252D structurefenfluramineC12H16F3N231.2624 / 13.4Yes
563322D structureCHEMBL2205833C17H18N2O266.3443 / 11.3Yes
569462D structureCHEMBL421283C22H26N2O334.4632 / 14.6Yes
5232162D structureCHEMBL3770342C14H18BrN5336.2372 / 32.3Yes
579912D structureCHEMBL2432053C19H22N2O294.3983 / 02.0Yes
592372D structureMLS000547944C19H21ClN4340.8553 / 03.5Yes
605162D structureCHEMBL253597C21H20N2O3347.4024 / 03.2Yes
610262D structure6,8,9-trimethyl-11H-indolo[3,2-c]quinolineC18H16N2260.341 / 14.8Yes
612702D structureCHEMBL3262407C20H27N3O325.4564 / 13.7Yes

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