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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameMelatonin receptor type 1C
SpeciesGallus gallus (Chicken)
Gene
SynonymCKB
Mel-1C-R
Mel1c receptor
DiseaseN/A for non-human GPCRs
Length346
Amino acid sequenceMERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
UniProtP49288
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3196
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 17
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
37272D structureCHEMBL127337C13H14Br2N2O2390.0752 / 23.3Yes
263602D structureCHEMBL123900C13H15BrN2O2311.1792 / 22.3Yes
545232D structure5-hydroxyethoxy-N-acetyltryptamineC14H18N2O3262.3093 / 30.1Yes
670982D structureMelatoninC13H16N2O2232.2832 / 20.8Yes
831502D structureCHEMBL30930C15H20N2O4292.3354 / 21.5Yes
994802D structureN-[2-(5-bromo-1H-indol-3-yl)ethyl]acetamideC12H13BrN2O281.1531 / 21.5Yes
1042752D structureCHEMBL33700C14H18N2O2246.312 / 11.5Yes
1644752D structureCHEMBL285477C14H18N2O3262.3093 / 21.6Yes
2058872D structureCHEMBL33869C19H20N2O2308.3812 / 13.2Yes
2147932D structureCHEMBL284158C13H16N2O216.2841 / 21.7Yes
2199052D structureCHEMBL34327C20H22N2O2322.4082 / 13.1Yes
2252702D structureN-ACETYL-6-METHOXYTRYPTAMINEC13H16N2O2232.2832 / 21.6Yes
2382942D structureCHEMBL283600C13H16N2O2232.2832 / 21.6Yes
3341812D structureN-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamideC12H13FN2O220.2472 / 20.9Yes
3749022D structureN-[2-(5-chloro-1H-indol-3-yl)ethyl]acetamideC12H13ClN2O236.6991 / 21.4Yes
4173682D structure2,4-dibromomelatoninC13H14Br2N2O2390.0752 / 23.3Yes
4397462D structureN-acetyl-4-methoxytryptamineC13H16N2O2232.2832 / 21.6Yes

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