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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameUrotensin-2 receptor
SpeciesRattus norvegicus (Rat)
GeneUts2r
SynonymUT receptor
urotensin II receptor
UR-II-R
UR-2-R
UII-R1
[ Show all ]
DiseaseN/A for non-human GPCRs
Length386
Amino acid sequenceMALSLESTTSFHMLTVSGSTVTELPGDSNVSLNSSWSGPTDPSSLKDLVATGVIGAVLSAMGVVGMVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIIATYVTKDWHFGDVGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLVLGTWLLALLLTLPMMLAIQLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYVRLARAYWLSQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHEAMPLTPETARIVNYLTTCLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCHSPGSPGSFLPSRVHLQQDSGRSLSSSSQQATETLMLSPVPRNGALL
UniProtP49684
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4921
IUPHAR365
DrugBankN/A

Known ligands

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Total entries: 182
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
8232D structureCHEMBL571683C30H33N3O4499.6116 / 04.6Yes
8242D structureCHEMBL577518C30H33N3O4499.6116 / 04.6Yes
8262D structureCHEMBL566389C30H33N3O4499.6116 / 04.6Yes
39632D structureCHEMBL237877C24H29N3O3407.5144 / 02.5Yes
71002D structure477313-09-0C19H21Cl2NO2366.2823 / 1N/AN/A
92102D structureSB-436811C23H29Cl2N3O2450.4044 / 14.5Yes
139582D structureCHEMBL1165735C52H69N11O11S21088.3115 / 130.0No
186552D structureCHEMBL238066C33H43ClN4O5611.186 / 14.9No
266772D structureCHEMBL1165767C51H66N12O12S21103.2816 / 14-2.5No
297492D structureSB 706375C20H22BrF3N2O5S539.36410 / 14.2No
371122D structureCHEMBL1165797C66H86N14O16S21395.6220 / 17-3.4No
397022D structureCHEMBL1163473C46H59N9O9S2946.15213 / 110.5No
447942D structureCHEMBL578207C29H38N6O5S582.729 / 22.6No
453682D structureCHEMBL565416C29H36N4O5S2584.759 / 13.5No
501602D structureCHEMBL569689C33H40N4O6S620.7659 / 14.0No
506212D structureCHEMBL500949C56H69N11O12S21152.3516 / 121.9No
547232D structureCHEMBL565388C38H44N6O5664.8078 / 25.0No
561042D structureCHEMBL3104467C48H63N9O10S2990.20514 / 10-0.2No
561062D structureCHEMBL3104466C48H63N9O10S2990.20514 / 10-0.2No
563852D structureCHEMBL584545C32H38N4O4542.687 / 14.0No
615312D structureCHEMBL567759C37H44N6O6S700.85510 / 24.7No
4443072D structureCHEMBL3315140C56H70N10O11S21123.3515 / 12-0.7No
4714642D structureCHEMBL3577310C32H34N4O4538.6486 / 51.9No
4714662D structureCHEMBL3577309C32H34N4O4538.6486 / 51.9No
697972D structureCHEMBL567075C31H38N4O4S562.7297 / 14.4No
722352D structureCHEMBL3104639C47H62IN9O10S21104.0914 / 110.7No
736642D structureCHEMBL566187C28H29N3O4471.5576 / 03.8Yes
822452D structureCHEMBL504097C57H72N10O10S21121.3814 / 122.4No
918732D structureCHEMBL566144C30H34N4O4514.6267 / 13.3No
4747462D structureCHEMBL3577304C30H30N4O4510.5946 / 42.3No
962392D structureCHEMBL237879C34H45ClN4O4609.2085 / 15.1No
963882D structureCHEMBL524855C58H72N10O10S21133.3914 / 122.5No
983442D structureCHEMBL392166C33H44N4O5576.7386 / 14.2No
4456552D structureCHEMBL3315142C56H70N10O11S21123.3515 / 12-0.7No
1081412D structureCHEMBL501579C56H70N10O10S21107.3614 / 122.1No
4766822D structureCHEMBL3577308C29H30N4O4498.5836 / 51.2Yes
4766852D structureCHEMBL3577307C29H30N4O4498.5836 / 51.2Yes
1123902D structureCHEMBL1163475C45H54N8O8S2899.09511 / 92.8No
1135962D structureCHEMBL437430C64H85N13O18S21388.5822 / 17-4.5No
4768982D structureCHEMBL593662C64H85N13O18S21388.5822 / 17-4.5No
4461632D structureurotensin-IIC64H85N13O18S21388.5822 / 17-4.5No
1155912D structureCHEMBL508811C57H71N11O12S21166.3816 / 122.3No
1157702D structureCHEMBL237878C29H31N3O3469.5854 / 13.8Yes
1159772D structureHuman U-IIC62H86N14O17S21363.5721 / 20-4.8No
4463272D structureCHEMBL3315151C52H65N11O11S21084.2816 / 12-2.6No
1193652D structureCHEMBL578203C32H42N4O5S2626.8319 / 04.7No
1267602D structureCHEMBL402303C25H31Cl2N3O460.4433 / 05.7No
1267622D structureCHEMBL254356C25H31Cl2N3O460.4433 / 05.7No
1289272D structureCHEMBL509009C57H70N10O10S21119.3714 / 122.2No
1303492D structureCHEMBL568388C36H39ClN4O6S2723.310 / 16.6No
1317182D structureCHEMBL567736C31H38N4O6S2626.78710 / 14.5No
4793822D structureCHEMBL3577302C29H28N4O4496.5676 / 42.0Yes
4472912D structureCHEMBL3315148C52H66Cl2N10O11S21142.1815 / 12-0.7No
4804332D structureCHEMBL3577311C30H32N4O4512.616 / 51.6No
4804352D structureCHEMBL3577312C30H32N4O4512.616 / 51.6No
4473512D structureCHEMBL3315139C52H68N10O12S21089.2916 / 13-2.3No
1435462D structureCHEMBL390094C52H68N10O12S21089.2916 / 13-2.3No
4473622D structureCHEMBL3315145C52H65N11O11S31116.3417 / 12-1.8No
4806592D structureCHEMBL3577306C31H32N4O4524.6216 / 51.6No
1478682D structureCHEMBL1165764C47H65N11O13S21056.2217 / 14-4.8No
4812402D structureCHEMBL3577303C32H32N4O4536.6326 / 42.7No
4475912D structureCHEMBL3315150C53H67N11O11S21098.3116 / 12-2.2No
1503132D structureCHEMBL565937C31H35N3O4513.6386 / 05.1No
1562122D structureCHEMBL565580C36H40N4O6S2688.85810 / 15.6No
1562142D structureCHEMBL568316C36H40N4O6S2688.85810 / 15.6No
1562162D structureCHEMBL568165C36H40N4O6S2688.85810 / 15.6No
1591782D structureCHEMBL1165793C41H50N8O8S2847.01912 / 10-0.2No
4830522D structureCHEMBL3577300C31H30N4O4522.6056 / 42.3No
1661592D structureCHEMBL577772C47H55N9O7S2922.13310 / 93.3No
1717552D structureCHEMBL1165766C50H63N11O12S21074.2415 / 13-1.3No
1741532D structureCHEMBL568358C38H48N4O6656.8248 / 16.0No
1765832D structureCHEMBL3104643C53H67N9O10S21054.2914 / 111.5No
4487442D structureCHEMBL3315147C51H65ClN10O11S21093.7115 / 12-1.7No
1806402D structureCHEMBL501794C54H75N11O10S21102.3815 / 130.6No
4488142D structureCHEMBL3315153C51H65N11O13S21104.2717 / 12-2.5No
1846002D structureCHEMBL236396C31H35N3O3497.6394 / 04.5Yes
1857392D structureCHEMBL1164032C25H32N4O6S516.6138 / 5N/ANo
1921682D structureCHEMBL504723C56H69ClN10O10S21141.814 / 122.7No
4867602D structureCHEMBL3577305C30H30N4O4510.5946 / 42.3No
2021112D structureCHEMBL578205C32H42N6O4574.7267 / 23.5No
2023962D structureCHEMBL241128C28H36ClN5O3526.0786 / 22.6No
2060942D structureCHEMBL1163460C53H69N11O13S21132.3217 / 14-3.2No
2104452D structureCHEMBL1165765C37H49N9O7S2795.97510 / 90.4No
2150622D structureCHEMBL452403C61H74N10O10S21171.4414 / 123.7No
2154542D structureCHEMBL509042C60H72N10O10S21157.4214 / 123.3No
2156102D structureCHEMBL392142C32H37N3O3511.6664 / 04.8No
2157182D structureJNJ-39319202C30H38N4O5S2598.7779 / 14.1No
2157222D structureCHEMBL1163359C30H38N4O5S2598.7779 / 14.1No
2226122D structureCHEMBL569688C37H46N4O6642.7978 / 15.6No
2238472D structureAc-WKY-NH2C28H36N6O5536.6336 / 70.8No
2271142D structureCHEMBL568123C31H40N4O3S548.7467 / 14.2No
2322622D structureCHEMBL1163467C59H79N13O16S21290.4820 / 17-4.7No
2364542D structureCHEMBL571537C33H42N4O5S2638.8429 / 04.8No
2404062D structureCHEMBL1165796C47H55N9O7S2922.13310 / 93.3No
2424992D structureCHEMBL569923C31H40N6O6S624.75710 / 12.9No
2425362D structureCHEMBL568637C31H40N4O5S2612.8049 / 14.5No
2466482D structureCHEMBL505358C61H74N10O10S21171.4414 / 123.7No
2469172D structureCHEMBL391354C36H41ClN4O5645.1976 / 15.4No
2487672D structureCHEMBL510618C57H71ClN10O10S21155.8214 / 123.1No
2489942D structureCHEMBL1165734C57H76N12O15S21233.4219 / 16-4.1No

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