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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameNeuropeptide Y receptor type 4
SpeciesHomo sapiens (Human)
GeneNPY4R
SynonymNPY4-R
neuropeptide Y receptor type 4
pancreatic polypeptide receptor 1
PP1
Y4 receptor
DiseaseObesity
Diabetes
Schizophrenia
Length375
Amino acid sequenceMNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI
UniProtP50391
Protein Data BankN/A
GPCR-HGmod modelP50391
3D structure modelThis predicted structure model is from GPCR-EXP P50391.
BioLiPN/A
Therapeutic Target DatabaseT27944
ChEMBLCHEMBL4877
IUPHAR307
DrugBankBE0002418

Known ligands

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Total entries: 198
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
3352D structureBDBM50442547C104H138N24O151964.420 / 196.9No
79122D structureCHEMBL349328C38H49IN4O2720.745 / 08.2No
88722D structureCID 73351118C184H287N53O53S24153.7661 / 58-13.6No
92402D structureCID 76335489C177H272N52O554008.4362 / 60-15.6No
138692D structureCHEMBL2440902C41H56N12O7828.9769 / 11-1.2No
138712D structureCHEMBL2440903C41H56N12O7828.9769 / 11-1.2No
146332D structureD0P9KPC180H279N53O544049.5361 / 61-14.9No
237472D structureCHEMBL585711C22H26FN5OS2459.6029 / 13.8Yes
350852D structureCHEMBL1774211C57H65F3N8O71031.1912 / 6N/ANo
377022D structureCHEMBL3040658C84H116N18O161633.9618 / 172.5No
382132D structureCHEMBL123410C22H24Cl2N2O403.3472 / 05.4No
386392D structureCHEMBL491762C23H26O4366.4574 / 13.6Yes
406682D structureBDBM50444592C177H272N52O554008.4362 / 56-17.1No
417142D structureCID 72711150C75H124N26O171661.9821 / 28-2.5No
4682032D structureCHEMBL3578016C143H215N39O282928.5434 / 412.0No
472342D structureCHEMBL2441114C35H45F3N8O5714.79110 / 8N/ANo
507912D structureCHEMBL121799C23H27ClN2O382.9322 / 05.3No
516822D structurePP31-36, HUMANC36H61N13O8803.96711 / 12-2.8No
585152D structureCHEMBL2440909C44H60F3N11O10960.02615 / 11N/ANo
585192D structureCHEMBL2440908C44H60F3N11O10960.02615 / 11N/ANo
588922D structureCID 73355619C86H117F3N18O181747.9823 / 18N/ANo
598702D structureCHEMBL1774344C57H64F3N9O7S1076.2513 / 7N/ANo
607192D structureCHEMBL2440191C76H120N28O161681.9821 / 29-2.5No
5233732D structureCHEMBL508974C32H38N6O6602.6927 / 63.4No
650002D structureBDBM85678C186H281N56O56+4197.6362 / 59-17.9No
650842D structureCHEMBL2440910C47H66F3N11O111018.1116 / 11N/ANo
650872D structureCHEMBL2440897C47H66F3N11O111018.1116 / 11N/ANo
668102D structureCHEMBL413871C111H159N37O182299.7325 / 34-0.6No
683552D structureCHEMBL470495C30H35N5O4529.6415 / 53.7No
698892D structureCHEMBL2440119C33H54N12O8746.87110 / 12-2.9No
710872D structureNPY2-36, porcineC181H278N54O554090.5462 / 58-17.7No
806032D structureCHEMBL2440902C43H57F3N12O9942.99914 / 12N/ANo
806062D structureCHEMBL2440903C43H57F3N12O9942.99914 / 12N/ANo
839952D structureCID 76313780C177H272N52O554008.4362 / 60-15.6No
841162D structureSub[-Tyr-Arg-Leu-Arg-Tyr-NH2]2C80H122N24O181708.0124 / 26-5.3No
841202D structureCHEMBL2371908C80H122N24O181708.0124 / 26-5.3No
845782D structureCHEMBL2440933C38H50F3N9O8817.86813 / 9N/ANo
855352D structureCID 73357159C88H105F3N18O141695.9219 / 18N/ANo
867352D structureCHEMBL1081469C18H18N4S2354.495 / 24.5Yes
912612D structureDes-AA10-17[Cys7,21, Pro34]-NPYC158H245N47O42S33571.1752 / 49-12.6No
934902D structureNPY D-Trp32C196H290N56O56S4358.8765 / 59-15.6No
966972D structureCHEMBL483251C19H15Cl2N3O2388.2484 / 14.7Yes
997772D structureCHEMBL83255C20H24FN3OS373.495 / 14.0Yes
1000622D structureCHEMBL331202C28H32ClN3O3494.0324 / 04.9Yes
1014972D structureCHEMBL497359C20H16F3N3O2387.3627 / 14.3Yes
1058562D structureBDBM50441969C75H119N25O171642.9421 / 24-2.8No
1072362D structureCHEMBL1774344C55H64N9O5S+963.2358 / 78.7No
1106132D structureBDBM50442552C86H104N18O121581.8916 / 197.7No
1125102D structureCID 16142386C135H209N41O362982.4142 / 48-6.6No
1132592D structureCHEMBL496327C21H19N3O4377.46 / 13.3Yes
1133782D structureBDBM50441961C75H124N26O171661.9821 / 25-3.7No
1178122D structureCHEMBL2440933C36H49N9O6703.8458 / 80.7No
1180422D structureBDBM50441960C73H119N27O181662.9322 / 26-6.6No
1243612D structureBDBM82300C195H302N58O57S+44402.9761 / 65-14.8No
1255882D structureBDBM50441962C76H126N26O171676.0121 / 25-3.3No
1280962D structureCHEMBL2440909C42H59N11O8846.00310 / 10-0.8No
1280982D structureCHEMBL2440908C42H59N11O8846.00310 / 10-0.8No
1288942D structurePYY13-36, porcineC135H208N40O393015.3945 / 49-8.3No
1307392D structureCHEMBL3040656C82H114N20O101539.9414 / 192.4No
1315142D structureBDBM50442573C86H120N22O161718.0420 / 20-0.4No
1315202D structureBDBM50442575C86H120N22O161718.0420 / 20-0.4No
1424192D structureCHEMBL2440936C31H39N5O4545.6845 / 63.0No
1538652D structureBVD 10C58H92N16O131221.4716 / 150.4No
1557802D structureCHEMBL2440935C38H50F3N9O6785.8711 / 9N/ANo
5260262D structureCHEMBL3785576C88H126F12N24O242132.140 / 32N/ANo
1588332D structureBDBM85680C182H281N58O54S2+4209.7261 / 60-19.4No
1622712D structureCHEMBL2440930C36H46F3N7O8761.813 / 8N/ANo
4834452D structureCHEMBL3578018C145H218N40O292985.5935 / 421.6No
1740442D structureCHEMBL82374C22H28FN3O2S417.5436 / 14.7Yes
1776262D structureCID 73348025C84H113F3N18O141655.9419 / 18N/ANo
1781612D structureCHEMBL2440905C44H61N13O8900.05510 / 12-2.0No
1781652D structureCHEMBL2440904C44H61N13O8900.05510 / 12-2.0No
1788602D structureBIBP3226C27H31N5O3473.5774 / 52.5Yes
1788662D structureCHEMBL2440929C27H31N5O3473.5774 / 52.5Yes
1815662D structureCHEMBL2440937C35H47N9O6689.8188 / 81.2No
1826272D structureCHEMBL340369C34H45ClN4O2577.215 / 15.9No
1834172D structureCID 73349571C88H121F3N22O181832.0723 / 20N/ANo
1834212D structureCID 73355616C88H121F3N22O181832.0723 / 20N/ANo
5501982D structureDB05045C185H288N54O55S24212.7899 / 667.8No
1930562D structureBDBM85679C184H287N53O54S2+24169.7659 / 56-13.1No
1939262D structureCHEMBL3040691C84H116N22O121625.9916 / 210.4No
1963312D structurePim[-Trp-Arg-Nva-Arg-Tyr-NH2]2C81H120N28O141710.0320 / 26-2.3No
1963352D structureCHEMBL2371910C81H120N28O141710.0320 / 26-2.3No
1963432D structureCID 72713074C76H123N25O171658.9821 / 27-1.0No
1965272D structureCHEMBL591971C57H90N16O131207.4516 / 16-2.2No
1965462D structureCID 44283143C108H172N34O22S22362.932 / 32-3.6No
1983282D structureCID 73443032C90H112N18O161702.019 / 185.5No
1983332D structureCID 73443030C90H112N18O161702.019 / 185.5No
1992522D structureCHEMBL2440937C37H48F3N9O8803.84113 / 9N/ANo
2000272D structureCHEMBL2440930C34H45N7O6647.7778 / 71.8No
2029502D structureBDBM50442557C82H112N18O161605.9120 / 171.4No
2045612D structureCHEMBL490937C19H14F2N4336.3465 / 12.3Yes
2076742D structureCHEMBL2440936C33H40F3N5O6659.70710 / 7N/ANo
2079622D structureCHEMBL491930C23H20N4O3400.4385 / 12.4Yes
2091262D structureCHEMBL3040675C82H112N18O121541.9114 / 175.2No
2129802D structureCHEMBL2440901C40H52F3N11O8871.9213 / 11N/ANo
2129822D structureCHEMBL2440900C40H52F3N11O8871.9213 / 11N/ANo
2136552D structureCID 73354074C80H127N25O161695.0620 / 260.2No
2146512D structureCHEMBL1784130C21H16F4N4O416.387 / 12.9Yes
4900402D structureCHEMBL3578017C139H206N38O282857.4233 / 402.1No

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