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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameD(4) dopamine receptor
SpeciesMus musculus (Mouse)
GeneDrd4
Synonymd(2C) dopamine receptor
D4 receptor
D4R
Dopamine D4 receptor
dopamine receptor 4
DiseaseN/A for non-human GPCRs
Length387
Amino acid sequenceMGNSSATEDGGLLAGRGPESLGTGAGLGGAGAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPAVCCLENRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPFFPDCPPPLPSLRTSPSDSSRPESELSQRPCSPGCLLADAALPQPPEPSSRRRRGAKITGRERKAMRVLPVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
UniProtP51436
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2574
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 24
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5362702D structureCHEMBL3915107C21H23ClN2O3386.8764 / 03.4Yes
5575982D structureSCHEMBL14060375C21H23ClN2O3386.8764 / 03.4Yes
5375962D structureCHEMBL3936182C21H27N3O2353.4665 / 02.8Yes
5594232D structureSCHEMBL14061923C20H25N3O2339.4395 / 02.7Yes
5486922D structureCHEMBL3969837C20H25N3O2339.4395 / 02.7Yes
5377612D structureCHEMBL3925231C21H27N3O2353.4665 / 02.8Yes
5493702D structureCHEMBL3986799C22H29N3O2367.4935 / 03.2Yes
5610572D structureSCHEMBL14060090C22H29N3O2367.4935 / 03.2Yes
5403692D structureCHEMBL3900699C22H26N2O4382.465 / 02.7Yes
5626562D structureSCHEMBL15746087C22H26N2O4382.465 / 02.7Yes
5421482D structureCHEMBL3947839C20H25N3O2339.4395 / 02.4Yes
5646142D structureSCHEMBL14149778C20H25N3O2339.4395 / 02.4Yes
5433362D structureCHEMBL3946540C21H25ClN2O2372.8934 / 04.1Yes
5657862D structureSCHEMBL14060296C21H25ClN2O2372.8934 / 04.1Yes
5437272D structureCHEMBL3979116C21H24N2O3352.4344 / 02.7Yes
5437592D structureCHEMBL3963122C20H24ClN3O2373.8815 / 03.0Yes
5661772D structureSCHEMBL14149623C20H24ClN3O2373.8815 / 03.0Yes
5441112D structureCHEMBL3986651C22H28N2O3368.4775 / 03.4Yes
5442282D structureCHEMBL3942898C21H25FN2O2356.4415 / 03.6Yes
5526872D structureCHEMBL3941323C21H27N3O2353.4665 / 03.1Yes
5693892D structureSCHEMBL14061568C21H27N3O2353.4665 / 03.1Yes
5467422D structureCHEMBL3897835C22H25ClN2O3400.9034 / 03.8Yes
5468562D structureCHEMBL3936595C20H23N3O3353.4225 / 01.7Yes
5475822D structureCHEMBL3946661C21H26N2O2338.4514 / 03.5Yes

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