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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameC-C chemokine receptor type 8
SpeciesHomo sapiens (Human)
GeneCCR8
SynonymGPRCY6
GPR-CY6
CMKBRL2
CKR-L1
ChemR1
[ Show all ]
DiseasePsoriasis
Length355
Amino acid sequenceMDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
UniProtP51685
Protein Data BankN/A
GPCR-HGmod modelP51685
3D structure modelThis predicted structure model is from GPCR-EXP P51685.
BioLiPN/A
Therapeutic Target DatabaseT20575
ChEMBLCHEMBL4596
IUPHAR65
DrugBankN/A

Known ligands

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Total entries: 214
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
32812D structureCHEMBL240249C26H28N4O3444.5355 / 13.7Yes
54732D structure4'-Chloro-2,2':6',2''-terpyridineC15H10ClN3267.7163 / 03.0Yes
64872D structureCHEMBL440956C22H24N4O2376.464 / 12.6Yes
66312D structureCHEMBL222062C27H31N3O4S493.6225 / 24.2Yes
86312D structureCHEMBL271127C29H33N3O3471.6015 / 04.8Yes
119562D structureCHEMBL393411C25H26N4O3430.5085 / 23.3Yes
121012D structureCHEMBL583843C29H33N3O4487.65 / 14.0Yes
139322D structureCHEMBL218218C28H32N4O5S536.6476 / 23.0No
187002D structureCHEMBL210322C27H30N2O3430.5484 / 14.7Yes
203992D structureCHEMBL218350C27H32N4O4S508.6375 / 34.0No
220022D structureCHEMBL270969C29H33N3O4487.65 / 03.8Yes
227872D structureCHEMBL387451C30H29N3O4S527.6395 / 25.0No
242402D structureCHEMBL221078C32H34N4O4S570.7086 / 25.2No
244432D structureCHEMBL221867C27H32N4O4S508.6376 / 32.7No
276762D structureCHEMBL396102C28H30N4O3470.5735 / 03.9Yes
309502D structureCHEMBL374527C31H38N4O5S578.7287 / 24.7No
317742D structureCHEMBL221130C27H30N4O4S506.6215 / 23.5No
344642D structureCHEMBL579072C26H32F2N4O2470.5657 / 13.4Yes
372542D structureCHEMBL376069C25H18N2O5S458.4886 / 14.2Yes
432772D structureCHEMBL384534C22H23N3O3S409.5045 / 13.0Yes
473612D structureCHEMBL240462C26H26N4O2426.524 / 13.9Yes
495792D structureCHEMBL259243C29H31ClN2O2475.0293 / 06.2No
496342D structureCHEMBL584087C25H32N4O3436.5566 / 13.0Yes
512262D structureCHEMBL245568C27H28N4O3456.5465 / 13.9Yes
512272D structureCHEMBL240848C27H28N4O3456.5465 / 13.9Yes
513492D structureCHEMBL218502C24H20N2O3S416.4954 / 14.7Yes
513782D structureCHEMBL568523C26H34N4O2434.5845 / 13.2Yes
526212D structureCHEMBL374978C28H33N3O4S507.6495 / 24.6No
530182D structureCHEMBL247762C29H29N3O3467.5695 / 05.0Yes
540072D structureCHEMBL245365C24H23Cl2N3O5S536.4247 / 04.3No
544882D structureCHEMBL426207C25H26N2O6S482.5517 / 14.4Yes
558132D structureCHEMBL397395C27H31N3O3445.5635 / 04.5Yes
574572D structureCHEMBL574655C28H32N4O3472.5896 / 04.1Yes
591412D structureNSC602850C14H10Br2N2366.0562 / 03.6Yes
592002D structure1,10-phenanthrolineC12H8N2180.212 / 01.8Yes
603362D structureCHEMBL566759C26H33N3O2419.5694 / 04.2Yes
648282D structureCHEMBL218036C25H27N3O5S481.5676 / 32.7Yes
669252D structure2,2':6',2''-TerpyridineC15H11N3233.2743 / 02.4Yes
701402D structureCHEMBL270971C29H33N3O4487.65 / 03.4Yes
707172D structureCHEMBL205447C31H37N3O3499.6555 / 24.6Yes
845972D structureCHEMBL385654C25H35N3O4S473.6325 / 23.9Yes
847772D structureCHEMBL374916C18H23N3O4S377.4596 / 22.3Yes
874442D structureCHEMBL376910C26H30N4O4S494.615 / 23.4Yes
876882D structureCHEMBL568294C29H40N4O2476.6655 / 14.6Yes
881902D structureCHEMBL409224C30H33ClN2O3505.0554 / 06.1No
941362D structureCHEMBL410885C27H30N4O2442.5635 / 04.1Yes
985662D structureCHEMBL386308C28H32N4O4S520.6486 / 33.5No
993762D structureCHEMBL567419C26H35N3O2421.5854 / 04.2Yes
997802D structureCHEMBL573216C28H32N4O3472.5896 / 04.1Yes
1051232D structureCHEMBL217979C25H27N3O4S465.5685 / 23.5Yes
1068332D structureCHEMBL385288C27H32N4O4S508.6375 / 34.1No
1093512D structureCHEMBL218555C25H28N4O4S480.5836 / 22.8Yes
1113542D structure1,10-phenanthroline-4,7-dicarbaldehydeC14H8N2O2236.234 / 01.4Yes
1127732D structureCHEMBL205457C32H37ClN2O3533.1094 / 17.3No
1202372D structureCHEMBL376846C21H22N2O3S382.4784 / 13.9Yes
1222592D structure128143-88-4C15H11N3O249.2734 / 11.3Yes
1254512D structureCHEMBL395424C25H26BrN3O3496.4055 / 04.4Yes
1275862D structureCHEMBL219433C29H33N3O4S519.665 / 24.9No
1296402D structureCHEMBL393721C28H30N4O3470.5735 / 14.3Yes
1297492D structureCHEMBL221841C28H33N3O2443.5913 / 24.6Yes
1314002D structureCHEMBL385287C23H19N3O3S417.4835 / 23.4Yes
1314232D structure78831-36-4C14H12N2O2240.2624 / 20.8Yes
1340572D structureCHEMBL247965C27H31N3O3445.5635 / 04.6Yes
1353942D structureCHEMBL381354C21H26N2O2338.4513 / 13.6Yes
1365662D structure4,4'-Dimethoxy-2,2'-bipyridineC12H12N2O2216.244 / 01.4Yes
1369622D structureCHEMBL220703C26H30N4O4S494.616 / 32.4Yes
1376522D structureCHEMBL240460C26H26N4O3442.5195 / 13.6Yes
1398662D structureCHEMBL271768C28H31N3O2441.5754 / 04.5Yes
1399682D structureCHEMBL583621C26H33N3O2419.5694 / 03.6Yes
1432382D structureCHEMBL221639C26H28FN3O4S497.5856 / 24.0Yes
1442822D structureCHEMBL374979C27H29N3O4S491.6065 / 23.8Yes
1449512D structureNeocuproineC14H12N2208.2642 / 03.3Yes
1452052D structureCHEMBL572537C24H29N3O2391.5154 / 02.9Yes
1498892D structureCHEMBL218037C25H27N3O5S481.5676 / 23.8Yes
1519842D structure4,7-Dimethyl-1,10-phenanthrolineC14H12N2208.2642 / 03.2Yes
5540582D structureViral macrophage inflammatory protein-IIC55H93N19O14S21308.5920 / 19-6.2No
1573072D structureCHEMBL568296C25H31N3O2405.5424 / 03.4Yes
1594002D structureCHEMBL221961C26H29N3O5S495.5946 / 23.3Yes
1663092D structureCHEMBL222112C24H27N5O4S481.5717 / 22.0Yes
1695212D structureCHEMBL271801C28H31N3O2441.5754 / 04.5Yes
1695532D structureCHEMBL387161C30H30N4O4S542.6545 / 34.8No
1718652D structureCHEMBL218503C23H24N2O3S408.5164 / 24.8Yes
1755082D structureCHEMBL219432C24H27N3O5S469.5566 / 22.9Yes
1768482D structureCHEMBL2205809C14H12N2208.2642 / 03.2Yes
1805832D structureCHEMBL567417C29H40N4O2476.6655 / 14.6Yes
1865892D structureCHEMBL373893C26H29N3O5S495.5946 / 24.2Yes
1867562D structureCHEMBL218375C26H29N3O5S495.5946 / 24.2Yes
1885632D structureCHEMBL375315C26H29N3O5S495.5946 / 24.2Yes
1888772D structureCHEMBL426551C26H29N3O4S479.5955 / 23.9Yes
1890472D structureCHEMBL218554C24H31N3O4S457.5895 / 23.2Yes
1901702D structureCHEMBL221978C26H28FN3O4S497.5856 / 24.0Yes
1902972D structureCHEMBL247964C25H27N3O3417.5095 / 03.8Yes
1907452D structureCHEMBL220650C26H35N3O4S485.6435 / 24.3Yes
1911752D structureCHEMBL221842C24H29N5O4S483.5876 / 22.3Yes
1921882D structureCHEMBL374939C27H31N3O4S493.6225 / 24.2Yes
1939582D structureCHEMBL375854C27H30N4O4S506.6216 / 32.7No
1950592D structureCHEMBL219327C26H29N3O4S479.5955 / 23.9Yes
1982722D structureCHEMBL221789C25H28N2O5S468.5686 / 14.4Yes
2003012D structureCHEMBL395423C26H26N4O3442.5196 / 03.5Yes
2169812D structureCHEMBL3091687C23H32N4364.5374 / 22.4Yes

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