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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProstaglandin E2 receptor EP1 subtype
SpeciesRattus norvegicus (Rat)
GenePtger1
SynonymEP1 prostanoid receptor
EP1 receptor
PGE receptor EP1 subtype
PGE2 receptor EP1 subtype
prostaglandin E receptor 1 (subtype EP1), 42kDa
[ Show all ]
DiseaseN/A for non-human GPCRs
Length405
Amino acid sequenceMSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
UniProtP70597
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5068
IUPHAR340
DrugBankN/A

Known ligands

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Total entries: 47
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5533062D structureAH 6809C17H14O5298.2945 / 13.9Yes
207862D structureSCHEMBL6118381C20H21ClN2O3372.8494 / 14.5Yes
5533702D structureprostaglandin D2C20H32O5352.4715 / 32.6Yes
451022D structureSCHEMBL6117410C20H15ClN2O4382.85 / 13.7Yes
503152D structureSCHEMBL6118481C21H18N2O3S378.4465 / 14.1Yes
541582D structureCHEMBL362851C23H16ClNO3S421.8955 / 15.8No
651382D structureSCHEMBL6118186C23H18FNO3375.3994 / 14.9Yes
805892D structureSCHEMBL6118436C20H21NO3323.3923 / 14.3Yes
5536792D structure17-phenyl-trinor-PGE2C23H30O5386.4885 / 32.8Yes
1002572D structurealprostadilC20H34O5354.4875 / 33.2Yes
1097852D structureSCHEMBL6117972C23H20N2O3372.4244 / 14.4Yes
1115052D structureUNII-U73BV4MML7C22H19ClNNaO3403.8384 / 0N/AN/A
5538432D structureILOPROSTC22H32O4360.4944 / 32.8Yes
1276112D structureSCHEMBL6118789C20H16N2O3S364.4195 / 13.7Yes
1344262D structureSCHEMBL6117580C23H18FNO3375.3994 / 14.9Yes
1422532D structureSCHEMBL6117628C23H19NO2341.412 / 15.1No
1472772D structureSCHEMBL6117837C21H17NO4347.374 / 13.8Yes
1569982D structureSCHEMBL6117306C21H16ClNO4381.8124 / 14.8Yes
1640142D structureSCHEMBL6117632C22H16F2N2O3394.3786 / 14.3Yes
5541532D structureSC 19220C16H14ClN3O3331.7563 / 22.3Yes
1739192D structureSCHEMBL6117584C23H18FNO3375.3994 / 14.9Yes
1926252D structureSCHEMBL6117311C23H18FNO3375.3994 / 14.9Yes
5542602D structureU 46619C21H34O4350.4994 / 23.9Yes
1981892D structureSCHEMBL6117461C22H16ClFN2O3410.8295 / 14.8Yes
2101462D structureSCHEMBL6118195C22H18N2O3358.3974 / 14.1Yes
2157742D structureSCHEMBL6117996C22H19NO4361.3974 / 14.6Yes
2176912D structureSCHEMBL6118235C21H16ClN3O3393.8275 / 13.6Yes
2290712D structureSCHEMBL6117454C19H14ClNO5371.7735 / 13.9Yes
5544422D structureDpt-prostaglandin E1C22H30O5374.4775 / 23.5Yes
2456382D structureSCHEMBL6117635C23H18FNO3375.3994 / 14.9Yes
2529852D structureSCHEMBL6117853C22H16F2N2O3394.3786 / 14.3Yes
2633242D structureSCHEMBL6118739C22H18N2O3358.3974 / 13.7Yes
5545992D structureenprostilC23H28O6400.4716 / 21.3Yes
5546302D structuredinoprostC20H34O5354.4875 / 42.7Yes
2801492D structureMK-2894C25H22F3NO3S473.517 / 25.9No
2807362D structureSCHEMBL6118477C21H16FNO4365.365 / 14.3Yes
3061922D structureCHEMBL467510C22H19ClNO3-380.8484 / 06.6No
3071292D structureSCHEMBL6117861C20H15ClN2O3S398.8615 / 14.4Yes
3090142D structureSCHEMBL6117314C21H16FN3O3377.3756 / 13.1Yes
3365312D structureSCHEMBL8762524C20H16N2O3S364.4195 / 14.2Yes
5549902D structureSulprostoneC23H31NO7S465.5617 / 31.5Yes
3786392D structureSCHEMBL6117257C22H16F2N2O3394.3786 / 14.3Yes
5552492D structureProstaglandin E2C20H32O5352.4715 / 32.8Yes
3995032D structureSCHEMBL6118263C22H17ClN2O3392.8394 / 14.7Yes
4217462D structureSCHEMBL6117615C22H16F2N2O3394.3786 / 14.3Yes
4367002D structureSCHEMBL6117558C23H19NO3357.4093 / 14.8Yes
4408012D structureSCHEMBL6117939C21H17NO3S363.4314 / 14.4Yes

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