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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 4
SpeciesMus musculus (Mouse)
GeneHtr4
Synonym5-HT-4
5-HT4
5-HT4 receptor
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
serotonin receptor 4
DiseaseN/A for non-human GPCRs
Length388
Amino acid sequenceMDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT
UniProtP97288
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2183
IUPHAR9
DrugBankN/A

Known ligands

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Total entries: 29
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5532632D structureBIMU-8C19H26N4O2342.4433 / 12.5Yes
69112D structureCHEMBL324057C20H28N4O2356.473 / 12.9Yes
5555212D structuretryptamineC10H12N2160.221 / 21.6Yes
5556132D structureCleboprideC20H24ClN3O2373.8814 / 23.2Yes
5535182D structurecisaprideC23H29ClFN3O4465.957 / 23.4Yes
5536512D structureZacoprideC15H20ClN3O2309.7944 / 21.7Yes
5536552D structureSDZ-205557C14H21ClN2O3300.7835 / 13.2Yes
909002D structureCHEMBL470432C19H25N3OS343.4894 / 05.2No
5537142D structureSC-53116C16H22ClN3O2323.8214 / 22.1Yes
5537942D structureRenzaprideC16H22ClN3O2323.8214 / 22.1Yes
5558992D structureRenzaprideC16H22ClN3O2323.8214 / 22.1Yes
5538612D structureDau 6285C17H21N3O4331.3725 / 12.1Yes
5540812D structure5-METHOXYTRYPTAMINEC11H14N2O190.2462 / 20.5Yes
5543352D structureGR 113808C19H27N3O4S393.5026 / 11.7Yes
5543642D structureBIMU-1C18H24N4O2328.4163 / 12.1Yes
5563372D structureCHEMBL62023C18H24N4O2328.4163 / 12.1Yes
5547202D structureserotoninC10H12N2O176.2192 / 30.2Yes
5567012D structureCHEMBL293468C16H20N4O2300.3623 / 21.6Yes
5548702D structure144625-67-2C19H26FN3O5S427.4918 / 22.2Yes
5548892D structuremetoclopramideC14H22ClN3O2299.7994 / 22.6Yes
3352522D structureCHEMBL325603C19H26N4O2342.4433 / 12.5Yes
3452052D structureCHEMBL35226C21H29N3O339.4834 / 14.5Yes
5550372D structureRO 116 1148C19H28N2O3332.4444 / 12.9Yes
5570242D structureRU-28253C14H16N2O228.2952 / 21.8Yes
5570532D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
5571852D structureR-76186C25H40ClN5O4510.0767 / 21.7No
5553302D structureCHEMBL130040C19H27NO4333.4285 / 03.5Yes
5572462D structureBDBM85018C19H29ClN3O2+366.913 / 23.0Yes
5572692D structureCHEMBL8197C17H20N2O2284.3593 / 13.8Yes

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