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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 1F
SpeciesMus musculus (Mouse)
GeneHtr1f
SynonymHTR1EL
5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
5-HT6
5-HT1F receptor
5-HT1F
[ Show all ]
DiseaseN/A for non-human GPCRs
Length366
Amino acid sequenceMDFLNASDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGIMITIVWVISVFISMPPLFWRHQGTSRDDECVIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVFLESGEKSIKLVSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRY
UniProtQ02284
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHAR5
DrugBankN/A

Known ligands

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Total entries: 11
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GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
266262D structureYohimbineC21H26N2O3354.454 / 22.9Yes
1711822D structure15532-75-9C11H13F3N2230.2345 / 12.3Yes
1748922D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
1756612D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
1767022D structureRU 24969C14H16N2O228.2952 / 21.8Yes
5544562D structure[125I]lysergideC20H24IN3O447.3372 / 13.6Yes
2903222D structureserotoninC10H12N2O176.2192 / 30.2Yes
3350042D structure(S)-mianserinC18H20N2264.3722 / 03.4Yes
3641132D structureBufotenineC12H16N2O204.2732 / 21.2Yes
3759622D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3882912D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No

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