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University of Michigan

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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Beta-2 adrenergic receptor
Species	Sus scrofa (Pig)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGQPGNRSVFLLAPNGSHAPDQDVPQERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGSFWCEFWISIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWVVSGLISFLPIKMHWYQATHREALNCYAEEACCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVARRQLQKIDKSEGRFHAQNLSQAEQDGRSGPGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHGIHDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRMAFQELLCLHRSSLKAYGNGCSSNSNGRTDYTGEQSGCYLGEEKDSERLCEDAPGPEGCAHRQGTVPDDSTDSQGRNCSTNDSML
UniProt	Q28997
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3801
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
11748	propranolol	C16H21NO2	259.349	3 / 2	3.0	Yes
50011	CHEMBL1203618	C27H32ClNO3	454.007	4 / 3	N/A	N/A
50019	CHEMBL1203604	C22H27ClN2O3S	434.979	6 / 3	N/A	N/A
81765	CHEMBL1203621	C27H32ClNO3	454.007	4 / 3	N/A	N/A
178969	CHEMBL1203599	C23H29ClN2O3	416.946	4 / 4	N/A	N/A
188237	CHEMBL348274	C27H29NO4	431.532	4 / 2	4.3	Yes
203400	CHEMBL1203620	C29H36ClNO3	482.061	4 / 3	N/A	N/A
232876	CHEMBL1202033	C30H35NO7	521.61	8 / 3	N/A	No
242864	CHEMBL1203607	C28H34ClNO3	468.034	4 / 3	N/A	N/A
243230	CHEMBL1203605	C22H30ClNO3	391.936	4 / 3	N/A	N/A
257224	CHEMBL1203608	C26H30ClNO3	439.98	4 / 3	N/A	N/A
269380	CHEMBL1203606	C21H28ClNO3	377.909	4 / 3	N/A	N/A
280788	CHEMBL1203619	C25H28ClNO	393.955	2 / 3	N/A	N/A
313953	VERAPAMIL	C27H38N2O4	454.611	6 / 0	3.8	Yes
322272	CHEMBL1203640	C29H34ClNO4	496.044	5 / 2	N/A	N/A
330134	CHEMBL160317	C28H33NO3	431.576	4 / 1	5.4	No
390541	CHEMBL1203610	C27H32ClNO2	438.008	3 / 2	N/A	N/A
405017	CHEMBL155739	C20H25NO3	327.424	4 / 2	3.1	Yes
417717	CHEMBL1203617	C26H28ClNO3	437.964	4 / 3	N/A	N/A

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