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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameSubstance-P receptor
SpeciesMeriones unguiculatus (Mongolian jird)
GeneTACR1
SynonymNK-1R
SPR
NK-1 receptor
Tachykinin receptor 1
DiseaseN/A for non-human GPCRs
Length407
Amino acid sequenceMDNVLPGDSDLFPNISTNSSESNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPGRVVCMIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYVKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEDEAEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNMLA
UniProtQ5DUB1
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1764942
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 55
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
4634582D structureCHEMBL3596492C28H27F3N2O464.5326 / 06.1No
4645352D structureAprepitantC23H21F7N4O3534.43512 / 24.2No
4650212D structureCHEMBL3596478C28H31F3N2O468.5646 / 16.0No
4657532D structureCHEMBL3596474C26H25ClF3NO459.9375 / 16.5No
4683582D structureCHEMBL3596483C27H25F3N2O450.5056 / 15.6No
4691212D structureSCHEMBL5446697C22H27N5O2393.4916 / 13.1Yes
4718562D structureCHEMBL3596447C21H25N5O2379.4646 / 12.9Yes
4721332D structureCHEMBL3596451C22H21F6N5O485.43411 / 14.5No
4750662D structureCHEMBL3596462C26H25F4NO443.4866 / 16.0No
4757082D structureCHEMBL3596475C28H28F3NO3483.5317 / 15.8No
4764182D structureCHEMBL3596496C34H31F3N2O540.636 / 07.6No
4770892D structureCHEMBL3596459C30H28F3NO475.5555 / 17.1No
4776152D structureCHEMBL3596493C29H29F3N2O478.5596 / 06.5No
4776412D structureCHEMBL3596465C27H28F3NO2455.5216 / 15.9No
4790752D structureCHEMBL3596467C27H25F3N2O450.5056 / 15.6No
4791102D structureCHEMBL3596479C26H25F3N2O3470.4927 / 15.7No
4797512D structureCHEMBL3596494C30H31F3N2O492.5866 / 06.9No
4798272D structureSCHEMBL3597978C22H24F3N5O431.4638 / 14.0Yes
4810202D structureCHEMBL3596482C27H28F3NO2455.5216 / 15.9No
4816692D structureCHEMBL3596471C26H26F3NO2441.4946 / 25.5No
4817212D structureCHEMBL3596473C27H25F6NO493.4938 / 16.8No
4817392D structureCHEMBL3596495C30H29F3N2O490.576 / 06.6No
4825382D structureCHEMBL3596476C26H25F4NO443.4866 / 16.0No
4836972D structureCHEMBL3596470C26H25F3N2O3470.4927 / 15.7No
4853252D structureCHEMBL3596490C26H24F3N3O451.4937 / 14.6Yes
4855842D structureCHEMBL3596486C27H23F5N2O486.4868 / 15.8No
4886612D structureSCHEMBL3591663C25H25F3N2O426.4836 / 14.9Yes
4899902D structureCHEMBL3596448C21H22F3N5O2433.4359 / 13.4Yes
2344722D structureNKP608C31H24ClF6N3O2619.9929 / 17.6No
4943072D structureCHEMBL3596463C27H28F3NO439.5225 / 16.3No
4960102D structureCHEMBL3596477C27H28F3NO439.5225 / 16.3No
4961632D structureCHEMBL3596461C26H25ClF3NO459.9375 / 16.5No
4963242D structureCHEMBL3596466C27H28F3NO439.5225 / 16.3No
4993252D structureCHEMBL3596484C27H24F4N2O468.4967 / 15.7No
5020802D structureCHEMBL3596480C28H30F3NO2469.5486 / 16.2No
5026012D structureCHEMBL3596455C26H26F3NO425.4955 / 15.9No
5026492D structureCHEMBL3596460C30H28F3NO475.5555 / 17.1No
5028012D structureCHEMBL3596457C24H24F3NO2415.4566 / 15.0Yes
5030952D structureCHEMBL3596458C23H23F3N2OS432.5057 / 15.0Yes
5033792D structureCHEMBL3596491C26H24F3N3O451.4937 / 14.9Yes
5042812D structureCHEMBL3596446C20H23N5O2365.4376 / 12.5Yes
5046192D structureCHEMBL3596487C27H21F7N2O522.46710 / 16.0No
5061462D structureCHEMBL3596452C21H22F3N5O417.4368 / 23.5Yes
5061962D structureCHEMBL3596454C22H24F3N5O431.4638 / 14.1Yes
5069592D structureCHEMBL3596485C27H23F5N2O486.4868 / 15.8No
5078442D structureCHEMBL3596488C27H24ClF3N2O484.9476 / 16.2No
5083202D structureCHEMBL3596469C26H27F3N2O440.516 / 25.2No
5092072D structureCHEMBL3596472C27H26F3NO3469.5047 / 15.7No
5092632D structureCHEMBL3596464C26H25F3N2O3470.4927 / 15.7No
5092992D structureCHEMBL3596468C26H25F4NO443.4866 / 16.0No
5093652D structureCHEMBL3596489C28H27F3N2O464.5326 / 16.0No
4026332D structureOrvepitantC31H35F7N4O2628.63610 / 05.4No
5130462D structureCHEMBL3596453C22H24F3N5O431.4638 / 13.6Yes
5154802D structureCHEMBL3596481C26H26F3NO2441.4946 / 25.5No
5156362D structureSCHEMBL3599336C25H25F3N2O426.4836 / 14.8Yes

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