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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 1D
SpeciesCavia porcellus (Guinea pig)
GeneHTR1D
Synonym5-HT-1D
5-HT1D
Serotonin receptor 1D
DiseaseN/A for non-human GPCRs
Length376
Amino acid sequenceMSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFTTAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATKTLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEDFRQAFQKVVHFRKAS
UniProtQ60484
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2304407
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 21
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
104482D structureSB 204070 hydrochlorideC19H27ClN2O4382.8856 / 13.5Yes
127882D structureCHEMBL72092C27H30N2O4446.5475 / 22.6Yes
216062D structureCHEMBL543964C16H16ClN3O301.7741 / 3N/AN/A
314132D structureCHEMBL306384C29H31N5O3497.5997 / 14.9Yes
593722D structureCHEMBL311150C29H34N4O3486.6165 / 14.1Yes
1792272D structureCHEMBL75642C22H21N5355.4453 / 13.8Yes
2074572D structureCHEMBL137485C15H20N2O244.3382 / 12.9Yes
2074622D structureCHEMBL133939C15H20N2O244.3382 / 12.9Yes
2210902D structureCHEMBL72088C24H26N4O2402.4985 / 13.2Yes
2365942D structureCHEMBL309021C24H27N3O2389.4994 / 13.9Yes
2432912D structure143797-63-1C15H14N4O266.3042 / 21.5Yes
2727532D structureCHEMBL72981C24H26N4O2402.4985 / 13.2Yes
2799292D structureSB 206553C17H16N4O292.3422 / 11.7Yes
2902762D structureserotoninC10H12N2O176.2192 / 30.2Yes
3081462D structureCHEMBL73446C30H36N2O5504.6276 / 15.1No
3271872D structureCHEMBL80189C18H19N5305.3853 / 12.8Yes
3595932D structureCHEMBL70355C27H32N2O3432.5644 / 24.5Yes
4071222D structure148672-13-3C29H31N5O3497.5997 / 14.9Yes
4359702D structureSerotonin-O-carboxymethyl-gly-tyrC23H27N5O5453.4996 / 60.6No
4366192D structure5-Methoxy-N,N-dimethyltryptamineC13H18N2O218.32 / 11.5Yes
4368032D structureCHEMBL72700C27H30N2O3430.5484 / 14.8Yes

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