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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameEndothelin-1 receptor
SpeciesMus musculus (Mouse)
GeneEdnra
SynonymETA receptor
ET-AR
ET-A
endothelin-1 receptor
Endothelin receptor type A {ECO:0000312|MGI:MGI:105923}
[ Show all ]
DiseaseN/A for non-human GPCRs
Length427
Amino acid sequenceMSIFCLAAYFWLTMVGGVMADNPERYSANLSSHMEDFTPFPGTEINFLGTTHRPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGELHRTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNNHNTERSSHKDSMN
UniProtQ61614
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2286
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 30
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
578182D structureCHEMBL347948C43H57N7O10831.96810 / 83.3No
806172D structureCHEMBL1672882C51H61FN4O171021.0621 / 13.2No
944232D structureCHEMBL594265C29H27BrO9599.439 / 14.7No
1008152D structureCHEMBL359235C47H59N7O10882.02810 / 94.5No
1008182D structureCHEMBL356864C47H59N7O10882.02810 / 94.5No
1118642D structureCHEMBL147510C43H60N8O11864.99812 / 11-0.7No
1146062D structureCHEMBL611626C36H34O12S690.71612 / 14.9No
1378962D structureCHEMBL151361C42H56N8O11848.95511 / 101.0No
1411862D structureCHEMBL433893C48H61N7O10896.05510 / 95.3No
1436242D structureCHEMBL149091C41H55N7O10805.9310 / 92.6No
1692182D structureCHEMBL148751C47H59N7O10882.02810 / 84.6No
1893512D structureCHEMBL594482C29H27FO9538.52410 / 14.3No
2100572D structureCHEMBL1672881C38H42FN3O12751.76115 / 13.1No
2190442D structureCHEMBL146866C49H60N8O10921.06510 / 105.1No
2252592D structureCHEMBL603635C29H27BrO9599.439 / 14.7No
2256892D structureCHEMBL1672880C35H39FO12670.68313 / 13.9No
2545842D structureCHEMBL147058C47H59N7O11898.02711 / 103.8No
2552362D structureCHEMBL593928C36H34O12S690.71612 / 14.9No
2665052D structureCHEMBL1672883C46H51FN4O13886.92717 / 15.0No
2704962D structureCI 1020C28H26O9506.5079 / 14.0No
3263242D structureCHEMBL1672885C44H47FN4O14S906.93218 / 23.5No
3414792D structureCHEMBL604286C29H27FO9538.52410 / 14.3No
3427672D structureCHEMBL1672886C38H42FN3O12751.76115 / 13.1No
3548072D structureCHEMBL444274C47H60N8O10897.04311 / 100.7No
3742692D structureCHEMBL1672884C45H49FN4O14S920.95918 / 13.7No
3850252D structureCHEMBL423941C43H60N8O10848.99911 / 100.5No
3857282D structureCHEMBL279259C43H60N8O10848.99911 / 10-0.4No
3857292D structureCHEMBL21253C43H60N8O10848.99911 / 10-0.4No
3857302D structureCHEMBL262782C43H60N8O10848.99911 / 10-0.4No
4325892D structureCHEMBL150719C45H61N9O10888.03611 / 110.6No

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